This essay discusses the notion of 'semiotic development in child development' and highlights potential concerns for 'psychologism' when semiotics turns into cognitive semiotics. The notion of 'semiotic development in child development' indicates a transdisciplinary approach involving both semiotics, the general study of meaning and signs, and child psychology. This, however, invites the criticism

This thesis investigates the integration of machine learning (ML)-based compression on Field-Programmable Gate Arrays (FPGAs) to enhance bandwidth compression of data, a crucial aspect in scientific research where large amounts of data are produced in real-time. The compression tool Baler, utilizing autoencoders for ML-based compression, is designed to handle scientific data efficiently. By combin

The reversal of the hydrolytic activity of α-mannosidase from jack bean has been studied in high concentrations of mannose. From an initial concentration of 85% mannose (w/w), a maximum yield of 70% (w/w) di- and oligosaccharides was obtained. The products were separated by gel chromatography and high-performance liquid chromatography, and characterized by gas-liquid chromatographymass spectrometr

β-d-Galp-(1→3)-d-GalNAc (1) was synthesised from lactose and GalNAc on a mmolar scale by transgalactosylation using β-d-galactosidase from bovine testes. The large proportions of unwanted oligosaccharides in the product mixture were removed by treatment with β-d-galactosidase from E. coli, which left 1, monosaccharides, and a small proportion of trisaccharides. Carbon-Celite chromatography then ga

Structural systems in seismic-prone regions can experience sudden deterioration caused by earthquake-induced ground-motion sequences. In addition, given the prevailing environmental conditions at their site, these systems may undergo gradual deterioration resulting from environment-induced mechanisms. The combined impacts of such phenomena can result in significant structural/non-structural damage

In the era of Industry 4.0, fostering innovation through strong collaboration among universities, industry, and government is crucial. However, the Tanzanian economy has faced challenges due to, among others, weak links between these entities. To address this, Sida initiated the Innovation Systems and Cluster Development Program (ISCP-Tz) in partnership with the University of Dar es Salaam. This w

Astrocytes play key roles in the brain. When astrocyte support fails, neurological disorders follow, resulting in disrupted synaptic communication, neuronal degeneration, and cell death. We posit that astrocytes overexpressing neurotrophic factors, such as Insulin Like Growth Factor 1 (IGF1), prevent the onset of neurodegeneration. We overexpressed IGF1 and the reporter TdTomato (TOM) in hippocamp

A search for charged-lepton-flavor violating Formula Presented (Formula Presented, Formula Presented) interactions is presented, considering both top-quark production and decay. The data analyzed correspond to Formula Presented of proton-proton collisions at a center-of-mass energy of Formula Presented recorded with the ATLAS detector at the Large Hadron Collider. The analysis targets events conta

Galβ1-3GlcNAc (1) and Galβ1-3GlcNAcβ-SEt (2) were synthesized on a 100 mg scale by the transgalactosylation reaction of bovine testes β-galactosidase with lactose as donor andN-acetylglucosamine and GlcNAcβ-SEt as acceptors. In both cases the product mixtures contained unwanted isomers and were treated with β-galactosidase from Escherichia coli which has a different specificity, under conditions f

The deterioration of engineering systems might reduce the system reliability and prompt maintenance operations that may disrupt the ability of the systems to provide regular service. Estimating the Remaining Useful Life (RUL) of the system requires an understanding of the deterioration processes acting on it. Recent formulations have shifted the focus of deterioration modeling from the system as a

Phylogenomic approaches have recently helped elucidate various insect relationships, but large-scale comprehensive analyses on relationships within sawflies and woodwasps are still lacking. Here, we infer the relationships and long-term biogeographic history of these hymenopteran groups using a large dataset of 354 UCE loci collected from 385 species that represent all major lineages. Early Hymeno

Background: A single learning algorithm can produce deep learning-based image segmentation models that vary in performance purely due to random effects during training. This study assessed the effect of these random performance fluctuations on the reliability of standard methods of comparing segmentation models. Methods: The influence of random effects during training was assessed by running a sin

In this paper, I try to reconcile the vulgar (normative) definition of punishment with the positivistic (purely descriptive) definition that separates the ethics of punishment from its definition—punishment positivism. I will argue that although the vulgar definition has critical issues, this does not mean that we should stop using normative concepts in the definition of punishment. I will attempt

Ultra-lean combustion is a promising strategy for enhancing engine efficiency and reducing pollutant emissions. In the present study, laminar burning velocity, SL, of n-heptane, a key gasoline surrogate component, was measured at 298 K and 1 atm using the heat flux method. The experimental conditions cover ultra-lean conditions with an equivalence ratio as low as 0.5 that have never been reported

BACKGROUND: There is increasing evidence implicating hemoglobin/heme and their scavengers in oxidative stress-mediated pathologies, but information is limited in abdominal aortic aneurysm (AAA).METHODS AND RESULTS: In this case-control study, we assessed heme/heme-related markers in 142 men with AAA and 279 men with a normal aortic diameter consecutively recruited from an ultrasound screening prog

Making use of the APOGEE DR17 catalogue with high quality data for 143 509 red giant branch stars we explore the strength of different mechanisms that causes a star to radially migrate in the Milky Way stellar disc. At any position in the disc we find stars that are more metal-rich than the local interstellar medium. This is surprising and normally attributed to the migration of these stars after

The use of pheromones, while common, remains underexplored in mosquito research. Understanding Aedes aegypti's mating behaviour and pheromones is crucial for expanding knowledge and advancing vector control strategies. Unlike other species, Aedes mosquitoes have adaptable mating behaviour, complicating the study of their communication mechanisms. Current literature on Aedes communication is sparse

Matematiker undersöker ofta talsystem som är annorlunda från de vanliga talen vi är vana vid. Ett exempel på ett sådant talsystem är timmarna på en klocka, där 13 = 1 och 9 + 6 = 3. Ett mindre självklart exempel är sekvenser av drag på en Rubik's kub. Man kan addera ihop två dragsekvenser genom att göra dem efter varandra, och det går att göra algebraiska manipulationer med dessa drag precis sThis thesis uses the strategy of Dyckerhoff-Kapranov to show the associativity and unitality of Hall Algebras for proto-abelian categories. After a more classical introduction to Hall algebras, we show that the Waldhausen S-construction of a proto-abelian category is a 2-Segal simplicial groupoid, and use this to construct a monoid object in the category of spans in groupoids. We then use this mon