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Background: Cartilage oligomeric matrix protein (COMP), an extracellular matrix glycoprotein, is vital in preserving cartilage integrity. Further, its overexpression is associated with the aggressiveness of several types of solid cancers. This study investigated COMP's role in ovarian cancer, exploring clinicopathological links and mechanistic insights.Methods: To study the association of COMP exp

In the dawning era of artificial intelligence (AI), health care stands to undergo a significant transformation with the increasing digitalization of patient data. Digital imaging, in particular, will serve as an important platform for AI to aid decision making and diagnostics. A growing number of studies demonstrate the potential of automatic pre-surgical skin tumor delineation, which could have t

Den här artikeln handlar om hur förtalsbrottet tillämpas på situa­tioner då en person berättar i sociala medier att hen har utsatts för våld eller sexuella övergrepp av en viss person. Inledningsvis diskuteras hur rättighets­skyddet enligt regeringsformen och Europakonventionen inverkar på tillämp­ningen av förtalsbrottet och de omständigheter som bör beaktas i avväg­ningen mellan rätten till resp

Background: Growing evidence indicates that young migrants are particularly vulnerable to sexual violence, however most research has focused on instances of sexual violence occurring in conflict zones and during transit. Much less attention has been given to the vulnerabilities to and experiences of sexual violence among young migrants in Europe.Objectives: To understand the scientific evidence re

Background: Well-developed vocabulary skills are crucial for academic success. Students having the language of instruction as a second language and students from lower socioeconomic backgrounds often have lower performance on vocabulary assessments. Teachers play an important role in supporting the vocabulary development of all students, regardless of background and educational needs.Aims: To inve

This article investigates the defence policies of the Nordic and Baltic countries from the perspective of shared security culture. To that end, the article analyses conceptualisations of total defence and resilience in a comparative perspective and inquires into existing and prospective regional cooperation in this area, in order to determine to what degree there exists a common security culture b

In situ gamma-spectrometric measurements were performed at grasslands (45 plots) and forests (6 plots) in the vicinity of the Belarusian nuclear power plant in September–October 2019. The aim of the study was to evaluate the baseline level of ambient dose equivalent rates of gamma radiation from natural radionuclides and 137Cs in the period preceding the commissioning of the NPP. The study reveale

Hydropower is a renewable and reliable energy source that can be utilized to fulfil energy demands and promote energy sustainability. In hydropower plants, Pelton turbines are installed at high-head and low-discharge sites. In Pelton turbines, needle, nozzle, buckets, and splitter are most exposed to silt erosion. An eroded turbine takes more discharge than rated for generating the same amount of

Background: Home haemodialysis (HHD) may be associated with important clinical, social or economic benefits. However, few randomised controlled trials (RCTs) have evaluated HHD versus in-centre HD (ICHD). The relative benefits and harms of these two HD modalities are uncertain. This is an update of a review first published in 2014. This update includes non-randomised studies of interventions (NRSI

A central role for sexual isolation in the formation of new species and establishment of species boundaries has been noticed since Darwin and is frequently emphasized in the modern literature on speciation. However, an objective evaluation of when and how sexual isolation plays a role in speciation has been carried out in few taxa. We discuss three approaches for assessing the importance of sexual

The ESC diagnostic criteria for infective endocarditis (IE) added spondylodiscitis as minor diagnostic criterion. Of patients with Staphylococcus aureus, streptococcal or Enterococcus faecalis bacteremia, 11 of 1807 episodes were reclassified to definite IE of which nine were not treated as IE. Spondylodiscitis as a minor criterion decreases specificity of the criteria.

The degraded resolution and sensitivity characteristics of background-oriented schlieren (BOS) can be recovered by utilizing an optical flow (OF)-based image processing scheme. However, the background patterns conventionally employed in BOS setups suit the needs of the cross-correlation approach, whereas OF is based on a completely different mathematical background. Thus, in order to characterize

Objective: Medical device industry payments to healthcare organisations (HCOs) can create conflicts of interest which can undermine patient care. One way of addressing this concern is by enhancing transparency of industry financial support to HCOs. MedTech Europe, a medical device trade body, operate a system of disclosure of education payments to European HCOs. This study aimed to characterise pa

Transitioning to low-input agricultural systems such as organic farming has been acknowledged as a way to mitigate negative effects of agriculture on biodiversity. However, the speed, magnitude and context dependence of biodiversity recovery after converting to organic farming remain uncertain. In this study, we explored the response of plant communities to time since transition to organic farming

Josephson diodes are superconducting elements that show an asymmetry in the critical current depending on the direction of the current. Here, we theoretically explore how an alternating current bias can tune the response of such a diode. We show that for slow driving there is always a regime where the system can only carry zero-voltage dc current in one direction, thus effectively behaving as an i

Spondyloarthritis (SpA) has been associated with comorbidities, e.g., cardiovascular disease. However, little is known about the relation between SpA and chronic obstructive pulmonary disease (COPD). The aim of the study was to compare the prevalence of COPD in SpA to the general population. Patients with prevalent SpA in Skåne, Sweden, on December 31, 2018, were identified based on diagnostic cod

Rice and quinoa starches are modified with short-chain fatty acids (SCFA) with different SCFA acyl chain lengths and levels of modification. This work is aimed to investigate the impact of modifying rice and quinoa starches with short-chain fatty acids (SCFAs) on various physicochemical properties, including particle size, protein and amylose content, thermal behavior, pasting characteristics, and

Neuromorphic computing promises to transform the current paradigm of traditional computing toward non-von Neumann dynamic energy-efficient problem solving. To realize this, a neuromorphic platform must possess intrinsic complexity reflected in the built-in diversity of its physical operation mechanisms. We propose and demonstrate the concept of a memlumor, an all-photonic device combining memory a