Popular Abstract in Swedish Typ 2 Diabetes (T2D) räknas som en folksjukdom i Sverige vilket innebär att den är så vanlig att minst 4 % av befolkningen är drabbad. Förekomsten av diabetes ökar lavinartat över hela världen och man beräknar att så många som 300 miljoner människor har diabetes idag. Socker är en livsviktig energikälla, men lagom är bäst Socker i mat förs ut till blodet och används soType 2 Diabetes (T2D) is characterized by dysregulated beta-and alpha-cell hormone secretion leading to elevated blood glucose levels. Several proteins are crucial in maintaining exocytosis of the hormone-containing granules such as Syntaxin1A (Stx1A), SNAP25, Munc-18 (Stxbp1) and the family of Synaptotagmins (Syts). The aim of this thesis has been to investigate functional and genetic events that

Context. Open clusters are key tools to study the spatial distribution of abundances in the disk and their evolution with time. Aims. Using the first release of stellar parameters and abundances of the Gaia-ESO Survey, we analyse the chemical properties of stars in three old/intermediate-age open clusters, namely NGC 6705, NGC 4815, and Trumpler 20, which are all located in the inner part of the G

Inom hälso- och sjukvården i Sverige implementeras ständigt nya styrmodeller. Många av dessa ger dock inte avsett resultat. I kapitlet diskuteras varför och hur styrmodeller omtolkas där kvalitetssäkring används som illustrativt exempel.

In this technical note we introduce a multivariable extension of a recently proposed model reduction algorithm for linear time-invariant systems. Reduced models are found by solving a convex. optimization problem with Linear Matrix Inequality constraints given a state space model or frequency samples of a model. In order to illustrate the method we apply it to a large-scale model of a deformable m

Popular Abstract in Swedish I ett ökande antal regioner i världen finns det arbetande barn som organiserar sig utifrån sin identitet som arbetande barn. Jag har studerat tre olika unioner i delstaten Karnataka i Indien, där jag har fokuserat på hur dom själva upplever mobiliseringen och vilka möjligheter de har att förändra sin situation inom existerande normer, traditioner och samhällsstrukturer.A number of working children in several regions over the world are mobilising to fight for better working conditions and to gain their rights according to how they interpret the Child Rights Convention (UNCRC) from 1989. Despite the increasing focus on child participation, their approaches and their demands are in many aspects controversial and they are often met with suspicion among diverse actor

Objectives: To investigate side by side the effects on serum lipoproteins and postprandial glucose and insulin concentrations of beverages enriched with 5 or 10 g of beta-glucans from oats or barley. Design and setting: An 8-week single blind, controlled study with five parallel groups carried out at two centres under identical conditions. Interventions: During a 3-week run-in period all subject

A linear quadratic stochastic control problem is considered. The problem involves several different controllers acting as a team, but with access to different measurements. Under appropriate assumptions on communication delays between the controllers, a quadratic control objective can be optimized using finite-dimensional convex optimization. Versions of this problem has been discussed in economic

Recent experiments on flapping flight in animals have shown that a variety of unrelated species shed a wake behind left and right wings consisting of both tip and root vortices. Here we present an investigation using Particle Image Velocimetry (PIV) of the behaviour and interaction of trailing vortices shed by paired, fixed wings that simplify and mimic the wake of a flying animal with a non-lifti

We compiled the available information on the occurrence and timing of migratory bat activity across the Baltic Sea and south-eastern North Sea coasts and islands, based on ultrasonic monitoring projects at 19 localities in 2007-2009. The data refer to three species; Nathusius' pipistrelle Pipistrellus nathusii, soprano pipistrelle P. pygmaeus and common noctule Nyctalus noctula. Pipistrellus nathu

Between AD 900 and AD 1200 Vikings, being able to navigate skillfully across the open sea, were the dominant seafarers of the North Atlantic. When the Sun was shining, geographical north could be determined with a special sundial. However, how the Vikings could have navigated in cloudy or foggy situations, when the Sun's disc was unusable, is still not fully known. A hypothesis was formulated in 1

Background Starting in the 1960s, a broad-based patients’ rights movement began to question doctors’ paternalism and to demand disclosure of medical information, informed consent, and active participation by the individual in personal health care. According to scholars, these changes contributed to downplay the biomedical approach in favor of a more patient-oriented perspective. The Swedish non-p

A new species, Ovealmbornia reginae from South Africa, is described, illustrated and compared with related species. A combined phylogenetic data set based on ITS and 28S nrLSU and 12S mtSSU sequences of the genera in the Dufourea clade is provided, (i. e. the genera Dufourea, Jackelixia, Langeottia, Ovealmbornia and Xanthokarrooa). Corrections of GenBank data for the genus Ovealmbornia and a key t

Non-Hodgkin lymphoma (NHL) remains one of the most common cancers in the US, with survival dependent on the type and stage of disease. B-cell lymphomas account for similar to 85% of all cases of NHL, and are commonly treated with chemotherapy, or monoclonal antibodies (mAbs) that t arget CD20 antigens on the surface of malignant tumors. The use of mAbs, either as single agents or in combination wi

We study the history of storminess in Northern Europe, as derived from local pressure observations in Lund since 1780 and Stockholm since 1820 ( Sweden). At both stations barometer readings were made three times per day, morning, midday and evening, and after about 1850 at fixed observation hours. We use four common storminess indices: annual number of deep lows ( p < 980 hPa), the annual 95th and