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Metabolic response to temperature variation in the great tit: an interpopulation comparison

1. We studied the resting metabolic rate (MR) from two great tit Parus major (Linnaeus) populations living in different winter regimes. Birds from the two different localities were exposed individually to +25 °C, 0 °C and −10 °C for the night in three consecutive sessions in random order. 2. Birds from Lund (Sweden) had a lower basal MR, as measured at thermoneutrality (+25 °C), than had birds fr

Does nociceptin play a role in pain disorders in man?

Nociceptin-immunoreactive cellbodies were detected in the human trigeminal ganglion, while no such fibers were identified in the temporal artery or in dermal tissue from the neck region. In four healthy subjects receiving nociceptin into the temporal muscle in an open labeled design no pain was detected. In 10 healthy subjects who received 200 pmol of nociceptin into tender non-dominant trapezius

The Unperturbed Oxo-Sulfido Functional Group cis-Mo(VI)OS, Related to that in the Xanthine Oxidase Family of Molybdoenzymes: Synthesis, Structural Characterization and Reactivity Aspects

The oxo-sulfido functional group cis-MoVIOS is essential to the activity of the xanthine oxidase family of enzymes but has proven elusive to synthesis in molecules containing no other four-electron ligands. A direct route to molecules containing this group has been achieved. The reaction system [MoO2(OSiPh3)2]/L in dichloromethane yields the complexes [MoVIO2(OSiPh3)2L] (L = phen (1), Me4phen (2),

Childhood sexual abuse. Women's health when starting in group therapy

Childhood sexual abuse has been shown to be common among adult women, 15-30% in prevalence studies, and among mentally ill women, 25-77%. These women often suffer from depression, anxiety, sexual and relationship problems. Suicide attempts and self-destructive behaviour are common. Within the Department of Psychiatry at Lund University Hospital, 45 women with experiences of childhood sexual abuse

Activation of latent protease function of pro-hK2, but not pro-PSA, involves autoprocessing

BACKGROUND: Human glandular kallikrein 2 (hK2) and prostate-specific antigen (PSA) are members of an extensive kallikrein family of proteases. Both proteases are secreted as zymogens or proenzymes containing a seven amino acid propeptide that must be proteolytically removed for enzymatic activation. The physiological proteases that activate pro-hK2 and pro-PSA are not known. METHODS: The pro-hK2 p

Rapid induction of apoptosis in B-cell lymphoma by functionally isolated human antibodies

Novel panning and screening methodology was devised to isolate high affinity human recombinant scFv antibody fragments with functionally associated properties in B lymphoma cells. The approach was used to generate a panel of apoptosis-inducing antibodies specific for antigens differentially expressed in B lymphoma vs. T leukaemia cells. The selections resulted in an antibody pool with near perfect

Formation of highly hygroscopic soot aerosols upon internal mixing with sulfuric acid vapor

The hygroscopic properties of submicron soot particles during internal mixing with gaseous sulfuric acid have been investigated using a combined tandem differential mobility analyzer (TDMA) and differential mobility analyzer-aerosol particle mass analyzer (DMA-APM) technique. Fresh particles exhibit no change in mobility size and mass at subsaturated conditions, whereas particles exposed to gaseou

Transition probabilities for some spectral lines of N III

Transition probabilities based on sophisticated configuration-interaction wave functions have been obtained for transitions between the 20 lowest lying fine-structure levels of the 2s(2)2p, 2s2p2, 2p3, 2s(2)3s, 2s(2)3p and 2s(2)3d states of N III. The calculations were performed using the CIV3 code of Hibbert, and small empirical adjustments were introduced to the diagonal Hamiltonian matrix eleme

Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells.

Peptidergic neurotransmission is slow compared to that mediated by classical neurotransmitters. We have studied exocytotic membrane fusion and cargo release by simultaneous capacitance measurements and confocal imaging of single secretory vesicles in neuroendocrine cells. Depletion of the readily releasable pool (RRP) correlated with exocytosis of 10%-20% of the docked vesicles. Some remaining ves

Beyond the public and private divide: remapping transnational climate governance in the 21st century

This article provides a first step towards a better theoretical and empirical knowledge of the emerging arena of transnational climate governance. The need for such a re-conceptualization emerges from the increasing relevance of non-state and transnational approaches towards climate change mitigation at a time when the intergovernmental negotiation process has to overcome substantial stalemate and

5-Hydroxytryptamine contracts human uterine artery smooth muscle predominantly via 5-HT2 receptors

Serotonergic receptors were classified in the isolated human uterine artery with intact endothelium, using agonists and antagonists for 5-hydroxytryptamine (5-HT) receptors. The efficacy for different agonists rated: alpha-methyl-5-HT (5-HT2) = 5-HT (non-selective) = 2-methyl-5-HT (5-HT3) >> sumatriptan (5-HT1), and the potency as: sumatriptan = 5-HT > 5-HT > alpha-methyl-5-HT > 2-methyl-5-HT. The

Prediction of species response to atmospheric nitrogen deposition by means of ecological measures and life history traits

1 The main objective of this study was to predict the responses of vascular plant species to atmospheric nitrogen deposition and enhanced soil nitrogen levels. The study was carried out in deciduous forests located in three regions of southern Sweden. The abundance of vascular plants, as well as soil pH and nitrogen mineralization rates, were studied in a total of 661 sample plots. 2 We calculated

HIV infection reduces skin graft survival in burn injuries: a prospective study

Impaired survival of skin grafts has been noted in human immunodeficiency virus (HIV) infected patients, but the reason is not known. Alterations in inflammatory response, which might be recorded as an imbalance in cytokine production, have been implicated. The aim of this study was to determine the impact of HIV infection in patients with burn injuries by comparison of split skin graft survival,

Impaired Insulin Exocytosis in Neural Cell Adhesion Molecule(-/-) Mice Due to Defective Reorganization of the Submembrane F-Actin Network

The neural cell adhesion molecule (NCAM) is required for cell type segregation during pancreatic islet organogenesis. We have investigated the functional consequences of ablating NCAM on pancreatic beta-cell function. In vivo, NCAM(-/-) mice exhibit impaired glucose tolerance and basal hyperinsulinemia. Insulin secretion from isolated NCAM(-/-) islets is enhanced at glucose concentrations below 15

Long-term outcome of displaced radial neck fractures in adulthood.

Background There have been no reports on the long-term outcome of radial neck Mason type IIIb fractures in adults. Methods 3 women and 2 men, aged 46 (22-69) years when they sustained a radial neck Mason type IIIb fracture, were evaluated after an average of 18 (16-21) years. All had been treated with radial head excision. Results 3 individuals had no subjective elbow complaints while 2 reported o

Early migrartion of acetabular components revised with cement.

Roentgen stereophotogrammetric analysis (RSA) was used to evaluate the migration in 17 cemented acetabular components after revision operations for mechanical loosening. All of the hips were examined four months and one year after surgery; ten of the hips were also examined after two years. In 15 of the 17 components, definite migration (0.5-2.7 mm) was identified, whereas two acetabular component

Single point extremal functions in Bergman-type spaces

Let A be a zero sequence for the Bergman space L-a(2) of the unit disc D, and let phi(A) be the corresponding canoniacal zero divisor. In this paper we consider quotients of the type phi(Au {alpha})/phi(A), alpha is an element of D. By use of methods from the theory of reproducing kernels we shall show that the modulus of such functions is always bounded by 3, and that they can be written as a pro