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A novel method for early-stage evaluation of adaptive reuse potential through functional division matching
The building sector accounts for a significant portion of global final energy use and greenhousegas emissions, demonstrating the need to find low-carbon alternatives to new construction.Adaptive reuse offers a sustainable alternative to new construction, yet early-stage assessmentsof reuse potential often rely on surface-level metrics, failing to consider a building's internalspatial logic. This p
Multi-input/multi-output switched-linear system identification from input–output data
In this paper, we propose a scheme to identify discrete-time, multi-input/multi-output switched-linear systems (MIMO-SLSs) from input-output measurements. The key step is an observer-based transformation to a switched auto-regressive with exogenous input (SARX) model. This transformation converts the state-space (SS) identification problem into a MIMO-SARX identification problem by compressing inf
The Numinous, the Political, and the Epistemic : Analytical Categories for Exploring the Historical Intersections of Spirituality, Ideology, and Knowledge
Historians of knowledge recognize that scientific knowledge is insepa- rable from ideology, which means that the intertwinement of the epistemic and the political constitutes a key topic of study. However, historians of knowledge have thus far not focused sufficiently on intersections with religiosity and spiritu- ality. To address this gap, this article introduces the numinous as a complemen- tar
Ex vivo stimulation of the trigeminal nucleus caudalis induces peripheral CGRP release in the trigeminal ganglion and reveals a distinct dopamine–endocannabinoid mechanism relevant to migraine
Background: Calcitonin gene-related peptide (CGRP) release from trigeminal structures is central to migraine pathophysiology. This study employed an ex vivo model preserving anatomical continuity between the trigeminal nucleus caudalis (TNC) and trigeminal ganglion (TG) to investigate (1) whether TNC stimulation induces peripheral CGRP release from the TG and (2) the potential involvement of a dis
Efficient cavity-mediated energy transfer between photosynthetic light harvesting complexes from strong to weak coupling regime
Excitation energy transfer between photosynthetic light-harvesting complexes is vital for highly efficient primary photosynthesis. Controlling this process is the key for advancing the emerging artificial photosynthetic systems. Here, we experimentally demonstrate the enhanced excitation energy transfer between photosynthetic light-harvesting 2 complexes (LH2) mediated through the Fabry-Pérot opti
Systematic review of post-COVID condition in Nordic population-based registry studies
The long-term effects of COVID-19, known as post-COVID condition (PCC), are still not fully understood. This systematic review synthesizes findings from Nordic registry studies to highlight long-term outcomes after COVID-19 infection. Twenty-two studies, primarily reflecting the pre-omicron and early vaccination phases, reveal increased primary care use for respiratory issues and fatigue in the su
Aetiology and antibiotic susceptibility of bacterial keratitis at a referral centre in southern Sweden
This was a retrospective cross-sectional study evaluating the aetiology and antibiotic susceptibility in patients treated for suspected bacterial keratitis at Skåne University Hospital during 2019. Inclusion criteria: eyes with bacterial keratitis. Exclusion criteria: co-infection with other microbes. Primary outcome parameters: predisposing factors, causative pathogens and antibiotic susceptibili
Excellent prospects : Arguing ‘value-added’ in research excellence proposals
Research excellence instruments (REIs) are among the most popular types of research funding in several research systems, including the Global South. A significant proportion of REIs is intended to promote pathbreaking or groundbreaking contributions. Specific research outcomes can often be traced back to a given project’s scientific objectives, but projections about the impact on the field and the
Attempted suicide short intervention program for older adults 65+ (ASSIP-OA) : a study protocol for a multicentre randomised controlled trial
Background: Older adults are underrepresented in suicide prevention research, even though suicide rates are higher in this age group (65+) than in any other age group in many countries worldwide. There are few clinical intervention studies that target this age group. A promising preventive intervention is the Attempted Suicide Short Intervention Program (ASSIP). Given differences in suicidal behav
Next generation multi-element monolithic Germanium detectors for spectroscopy : First integration at ESRF facility
The XAFS-DET work package of the European LEAPS-INNOV project is developing high-purity Germanium detectors for synchrotron applications requiring spectroscopic-grade response. The detectors integrate three key features: (1) newly designed monolithic Germanium sensors optimized to mitigate charge-sharing events, (2) an improved cooling and mechanical design structure supported by thermal simulatio
Gene sco1417 encodes a positive regulator of the de novo biosynthesis of pyridoxal 5ʹ-phosphate (vitamin B6) in Streptomyces coelicolor M145
Background: Actinomycetes of the genus Streptomyces are renowned for their highly developed and diverse specialized metaboliс pathways, and there is an extensive body of data on their specific and pleiotropic levels of regulation. Much less is known about routes leading to essential metabolites in this genus. In this work, we focused on elucidating the function of the highly conserved across Strep
“When You Feel Like There is No Trust in the Profession” : Midwives and Obstetricians Facing Complicated Cases
This study examines how two collaborating professions, midwifery and obstetrics, are influenced by women requesting caesarean sections. The empirical material consists of semi-structured interviews with Swedish midwives (n=6) and obstetricians (n=6). Analysed through Tilly’s terms, the categorical pair and triad, midwife and obstetrician function as complementary categories in a triad with the wom
Real-Time Brain-Computer Interfaces
A brain-computer interface (BCI) is a real-time system that converts a user’s brain activity into commands, enabling control over applications such as moving a cursor on the screen. This conversion is made possible by machine learning techniques and other algorithms. Historically, BCI research has focused on the analysis of brain signals offline. However, increasing computational power and algorit
Migrant welfare recipients managing their own scarce resources and those of others : a case of food uncertainty
Considering increasing living costs and lagging compensation levels in the welfare system, people on social welfare have difficulties accessing food to the extent needed. This presentation is based on a Swedish study aimed to reveal how migrant welfare recipients act, react, and reason in their management of their own scarce resources and those of others. Striving for ‘dignity’ took a prominent pl
Galactic Disc Dynamics and Structure : Analysis of the Phase Spiral and Vertical Scale-heights
The Milky Way provides the most detailed laboratory we have access to for studying the processes of galaxy formation and evolution. Modern large-scale surveys, most notably the Gaia mission, have revolutionised this field by revealing the extent to which the Galaxy is not a steady system, but dynamically active and rich in non-equilibrium features that preserve traces of past interactions. Underst
Awareness of how I am and how I want to be when communicating with people in need of care - Nursing students' experiences of theoretical and practical training in person-centred communication
AIM: To explore nursing students' experiences of what they had learned and gained through participating in simulation-based communication training anchored in person-centred values.BACKGROUND: Person-centredness is a core component of nurses' work and an important part of it is person-centred communication. To promote patients' wellbeing and comfort, nursing students must become prepared during th
Introduction: Gender, Archiving, and Knowledge Production after the Holocaust : A Postwar Republic of Letters?
The fourth issue of the yearbook History of Intellectual Culture (HIC) features a thematic section on the production of knowledge related to the Holocaust. The contributions focus on the circulation of knowledge via letters and other forms of written communication within and among survivor historical commissions after the Second World War with an emphasis on the interplay of gender and other diffe
Loss and damage in fisheries : Building on fishers’ situated knowledge to inform ways of knowing
Loss and damage in fisheries is acknowledged in climate change policy and science but is both undefined and contested, and there is a lack of empirical exploration of the topic. This paper presents the first in-depth, empirical analysis of how fishers’ situated knowledge of socio-ecological changes can inform our understanding of loss and damage in fisheries. The paper conducts a case study from M
Structural characterization of an extracellular contractile injection system from Photorhabdus luminescens in extended and contracted states
Contractile injection systems (CISs) are phage tail-like nanosyringes that mediate bacterial interactions by puncturing target cell membranes. Within these systems, Photorhabdus Virulence Cassettes (PVCs) can translocate toxins across eukaryotic target cell membranes and have been engineered to deliver diverse protein cargoes into non-natively-targeted organisms. Despite the structural insights in
