Death mechanisms compromising hippocampal neurogenesis after status epilepticus
Status epilepticus (SE) leads to neurodegeneration as well as neurogenesis in the adult rat hippocampus. This thesis demonstrates that even if the neurogenic response initially is very pronounced, with a several-fold increase in cell proliferation, the survival of the newly formed neurons is compromised by a death mechanism involving mitochondria-related caspases. This conclusion is based on immun