Background: Gastric Cardiac Cancer (GCC) has high incidence and poor prognosis requiring early screening of high-risk populations. Minichromosome maintenance (MCM) proteins are used as diagnostic-biomarkers in many cancers but not validated for GCC. We evaluate MCM protein 2 (MCM2), comparing it with the validated markers Ki67 and PCNA. Methods: GCC and corresponding cardiac precancerous samples w

Objective: To compare mortality rates between immigrant and native-born residents of Andalusia between 2006 and 2010, and to characterize mortality by cause. Material and methods: The data consisted of deaths from mortality statistics by cause, and the aggregated populations registered in the lists of inhabitants by country of birth in the case of native-born individuals and immigrants (with immig

Purpose – To identify and describe the strategic potential of logistics-driven packaging innovation in retail supply chains, and suggest propositions for further research and development, providing practitioners with a better basis on which to make strategic packaging and logistics decisions. Design/methodology/approach – An in-depth case study was conducted at a large global retailer which had im

The resolution and fidelity of global chronostratigraphic correlation are direct functions of the time period under consideration. By virtue of deep-ocean cores and astrochronology, the Cenozoic and Mesozoic time scales carry error bars of a few thousand years (k.y.) to a few hundred k. y. In contrast, most of the Paleozoic time scale carries error bars of plus or minus a few million years (m. y.)

α1-microglobulin (A1M) is a 26 kDa plasma and tissue protein with reductase activity and radical- and heme-binding anti-oxidative functions. In addition, exposure of A1M to hemoglobin has been shown to induce proteolytic elimination of a C-terminal tetrapeptide yielding a heme-degrading form, truncated A1M (t-A1M). Myeloperoxidase (MPO), a heme-containing enzyme that catalyzes the production of fr

Gravitational scattering in the ADD-model is considered at both sub- and transplanckian energies using a common formalism. By keeping a physical cut-off in the KK tower associated with virtual KK exchange, such as the cut-off implied from a finite brane width, troublesome divergences are removed from the calculations in both energy ranges. The scattering behavior depends on three different energy

Macroporous hydrogels (MHs), cryogels, are a new type of biomaterials for tissue engineering that can be produced from any natural or synthetic polymer that forms a gel. Synthetic MHs are rendered bioactive by surface or bulk modifications with extracellular matrix components. In this study, cell response to the architecture of protein ligands, bovine type-I collagen (CG) and human fibrinogen (Fg)

The effect of friction between the dowel and the surrounding timber was studied for single dowel-type joints. The joints tested were divided into two groups of joints, where the surface of the dowels differed. For the first group, the dowels had a smooth surface and for the second group the dowels had a rough surface. A contactfree measurement technique was used in the experimental investigation.

The present study characterizes immune cell populations in mice chronically infected with Salmonella. Mice were characterized as chronically infected based on persistently high titers of Salmonella-reactive immunoglobulins in the serum > 6 months after a single oral dose of S. enterica serovar Typhimurium. These mice had a visibly enlarged spleen but not liver, while both organs harbored bacteria

Under anaerobic conditions, Saccharomyces cerevisiae uses NADH-dependent glycerol-3-phosphate dehydrogenase (Gpd1p and Gpd2p) to re-oxidize excess NADH, yielding substantial amounts of glycerol. In a Δgpd1 Δgpd2 double-null mutant, the necessary NAD+ regeneration through glycerol production is no longer possible, and this mutant does not grow under anaerobic conditions. The excess NADH formed can

It has been suggested that a single photon can interfere with itself even if the difference between the two paths in the interferometer is larger than the “length” of the photon [Kessel’ and Moiseev, JETP Lett. 58, 81 (1993)]. The interference is regained by detecting the photons using a photon-echo process, where the absorbing atoms will, effectively, act as narrow-band filters. Such an experimen

The dynamic crack growth in ductile steel is investigated by means of the impact loaded 3 point bending (3PB) specimens. Results from experiments and numerical simulations are compared to each other. A modified 3PB specimen designed with the reduced width at its ends has been developed in order to avoid the initial compressive loading of the crack tip and also to avoid the uncertain boundary condi

Design. In a longitudinal study, 335 children ages 8, 11 and 14, first studied in 1989 were followed-up on two occasions in 1991 and 2002. The subjects filled in questionnaires on pain, the first two times in school, the last as a postal survey. Purposes. To determine if headache and back pain during the school years were transitory or if they grew into pain problems in adulthood; to determine pre

Many common diseases are known to have genetic components, but since they are non-Mendelian, i.e. a large number of genetic factors affect the phenotype, these components are difficult to localize. These traits are often called complex and analysis of siblings is a valuable tool for mapping them. It has been shown that the power of the affected relative pairs method to detect linkage of a disease

Two different self-adjoint Pauli extensions describing a spin-1/2 two-dimensional quantum system with singular magnetic field are studied. An Aharonov-Casher type formula is proved for the maximal Pauli extension and the possibility of approximation of the two different self-adjoint extensions by operators with regular magnetic fields is investigated.

Objective: The aim was to describe the patients' own experiences of risk information in connection with cardiac surgery and it's outcome. Methods: Questionnaires were answered prior to and 8 weeks after cardiac surgery. Data were analysed using qualitative content analysis. Patients in the intervention group (n = 55) received standard information and a newly written extended information brochure a

In 1985 Siegenthaler introduced the concept of correlation attacks on LFSR based stream ciphers. A few years later Meier and Staffelbach demonstrated a special technique, usually referred to as fast correlation attacks, that is very effective if the feedback polynomial has a special form, namely, if its weight is very low. Due to this seminal result, it is a well known fact that one avoids low wei

To every analytic function $g$ in the unit disk $\bold D$ one associates the integral operator $T_g(f)(z)\coloneq z^{-1}\int^z_0f(\xi)g'(\xi)d\xi$ on spaces of analytic functions in $\bold D$. Operators of this form appear naturally in complex analysis. For instance, the choice $g(z)\equiv z$ leads to the integration operator, and the choice $g(z)=\log(1/(1-z))$ leads to the Cesàro operator. The