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Early diagenesis and isotopic composition of lead in Lake Laisan, northern Sweden

Water column (dissolved/suspended phase, sediment traps) and sediment data (pore-water, solid-phase sediment) were combined with stable Pb and Pb-210 isotope data to trace the early diagenetic behaviour and geochemical cycling of Pb in Lake Laisan, a lake which has received large quantities of anthropogenic Pb since the early 1940s. Early diagenetic remobilisation of Pb is indicated by a subsurfac

Artemia salina as test organism for assessment of acute toxicity of leachate water from landfills

Artemia salina has, for the first time, been used as test organism for acute toxicity of leachate water from three landfills (the municipal landfills at Kristianstad, Sweden and Siauliai, Lithuania, and an industrial landfill at Stena fragmenting AB, Halmstad, as well as for leachate from Kristianstad treated in different ways in a pilot plan). Artemia can tolerate the high concentrations of chlor

Long-term prophylaxis in von Willebrand disease

The majority of patients with von Willebrand disease (VWD) have a mild bleeding tendency that primarily involves mucosal bleeding. Some patients with the disorder, however, have severe episodes of mucosal or joint bleeding that can hamper daily activities and lead to significant joint impairment. Experience in the setting of severe hemophilia has shown the feasibility and benefits of prophylactic

Utilization of organic nitrogen at two different substrate pH by different ectomycorrhizal fungi growing in symbiosis with Pinus sylvestris seedlings

The aim of this study was to test the potential of four isolates of ectomycorrhizal (EM) fungi to utilize organic nitrogen (N) at two different substrate pHs. The organic N source ((1)5N labelled lyophilised fungal mycelium) was mixed with either untreated peat/sand mixture (pH 4.9) or peat/sand mixture limed to a pH of 5.9 and put in cylindrical containers added to each pot. The content of the co

Serious, frightening and interesting conditions: differences in values and attitudes between first-year and final-year medical students.

CONTEXT AND OBJECTIVE: During medical education and training, the values and attitudes of medical students are shaped both by knowledge and by role models. In this study, the aim was to compare the views of first- and final-year students concerning patients with different medical conditions. PARTICIPANTS AND METHOD: In the spring of 1998 all first- and final-year medical students at Göteborg and L

Is Levoglucosan a Suitable Quantitative Tracer for Wood Burning? - Comparison with Receptor Modeling on Trace Elements in Lycksele, Sweden

Particle emissions from residential wood combustion in small communities in Northern Sweden can sometimes increase the ambient particle concentrations to levels comparable to densely trafficked streets in the center of large cities. The reason for this is the combination of increased need for domestic heating during periods of low temperatures, leading to higher emission rates, and stable meteorol

Social capital, trust in the health-care system and self-rated health: The role of access to health care in a population-based study.

This paper investigates the relationship between institutional trust in the health-care system, i.e. an institutional aspect of social capital, and self-rated health, and whether the strength of this association is affected by access to health-care services. The 2004 public health survey in the Scania region of Sweden is a cross-sectional study; a total of 27,963 respondents aged 18–80 years answe

Adjuvant oil induces waves of arthritogenic lymph node cells prior to arthritis onset.

A single intradermal injection of the adjuvant-oil squalene induces T cell mediated arthritis in DA rats. The chain of events leading from nonspecific provocation of the immune system to arthritis is largely unknown. Previous studies have demonstrated that lymph node (LN) cells are of pathogenic importance, i.e. cells from LNs draining the injection site can transfer arthritis to naïve DA rats. Re

Characterisation of two novel cyclodextrinases using on-line microdialysis sampling with high-performance anion exchange chromatography

In this work, a real-time sampling/analytical method for on-line measurements of two newly discovered cyclomaltodextrinases (CDases) has been developed and evaluated. This novel methodology not only allows the final products to be investigated, but it also reveals enzyme-specific differences in the degradation pathways during the hydrolysis of different substrates, which is a great advantage in th

Clinical characteristics in relation to final amputation level in diabetic patients with foot ulcers: a prospective study of healing below or above the ankle in 187 patients

The aim of this study was to describe the clinical characteristics in relation to final amputation level in diabetic patients with foot ulcers. In a prospective series, 187 consecutively presenting patients were investigated. From admission until final outcome, the patients were treated by a multidisciplinary team both as in- and out-patients. All the patients had one or more signs of neuropathy a

Bacterial growth on photochemically transformed leachates from aquatic and terrestrial primary producers

We measured bacterial growth on phototransformed dissolved organic matter (DOM) leached from eight different primary producers. Leachates (10 mg C liter(-1)) were exposed to artificial UVA + UVB radiation, or kept in darkness, for 20 h. DOM solutions were subsequently inoculated with lake water bacteria. Photoproduction of dissolved inorganic carbon (DIC), ranging from 3 to 16 mug C liter(-1) h(-1

Processing acoustic change and novelty in newborn infants

Research on event-related potential (ERP) correlates of auditory deviance-detection in newborns provided inconsistent results; temporal and topographic ERP characteristics differed widely across studies and individual infants. Robust and reliable ERP responses were, however, obtained to sounds (termed 'novel' sounds), which cover a wide range of frequencies and widely differ from the context provi

En människas uttryck. Studier i Hans Ruins självbiografiska essäistik

Popular Abstract in Swedish I den första avhandlingen på svenska om den finlandssvenske estetikern, filosofen och författaren Hans Ruin (1891–1980) förenas ett intresse för det litterära uttrycket med ett intresse för människan bakom orden. Litteraturen som mänskligt dokument, som spåret efter en människa, och dess funktion som överbringare av erfarenheter och insikter står i centrum för framställThe first dissertation in Swedish of the Finno-Swedish aesthetician, philosopher and writer Hans Ruin (1891–1980) combines an interest in the literary expression with an interest in the man behind the words. Literature as a human document, as the footprint of a human being, and its function as a bearer of experiences and insights is at the heart of the characterisation. The title of this dissertat

Carbon monoxide oxidation on copper oxide thin films supported on corrugated cerium dioxide {111} and {001} surfaces

Thin films of CeO2 with and without a thin layer of copper oxide were prepared by rf magnetron sputtering on surfaces of alpha-Al2O3 (sapphire) substrates. Careful characterisation of the surfaces was performed down to the atomic level using high-resolution electron-microscopy, atomic force microscopy, and X-ray photoelectron spectroscopy. Surprisingly, the as-deposited, corrugated ceria surfaces,

Residence time distribution characterization of the flow structure in dissolved air flotation

A numerical and analytical investigation is performed on a dissolved air flotation (DAF) pilot tank by using the residence time distribution (RTD) of the conservative dye rhodamine measured with a fluorometer. The experiments are numerically analyzed with regard to the total volume of the DAF tank separation zone in order to detect differences between observed separation zone flow structures in pr

General transition-state force field for cytochrome p450 Hydroxylation

We have developed force-field parameters for the hydrogen-abstraction transition state of aliphatic hydroxylation by cytochrome P450 using the Q2MM approach. The parametrization is based on quantum chemical (B3LYP) transition-state structures and Hessian matrices for 24 diverse substrate models (14 in the training set and 10 in the test set). The force field is intended to be applicable to any dru

A probabilistic treatment of the missing spot problem in 2D gel electrophoresis experiments

Two-dimensional SIDS-PAGE gel electrophoresis using post-run staining is widely used to measure the abundances of thousands of protein spots simultaneously. Usually, the protein abundances of two or more biological groups are compared using biological and technical replicates. After gel separation and staining, the spots are detected, spot volumes are quantified, and spots are matched across gels.

Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line.

Mutations in alpha-synuclein have been linked to rare, autosomal dominant forms of Parkinsons disease. Despite its ubiquitous expression, mutant alpha-synuclein primarily leads to the loss of dopamine-producing neurons in the substantia nigra. Alpha-synuclein is a presynaptic nerve terminal protein of unknown function, though some studies suggest it is important for synapse formation and maintenan