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Pituitary Adenylate Cyclase Activating Peptide (PACAP): An Experimental Study On the Expression and Regulation in the Peripheral Nervous System.

This thesis deals with PACAP and PACAP type-1 receptors in the sensory and autonomic parts of the peripheral nervous system. In the rat, PACAP is expressed in small-sized sensory neurons and in C-fibers. Unilateral transection of the sciatic nerve (axotomy) causes an upregulation of PACAP in medium-sized and large neurons, whereas the density of PACAP-IR fibers is decrea sed in the dorsal horn. In

Why Focus on Roles when Developing Future ERP systems

Abstract in UndeterminedIn this paper the question “Why software vendors focus on roles when they aim at developing the future enterprise resource planning (ERP) systems?” is discussed. At the moment there is increasing interest in developing ERP systems that support a person's different working roles in the organisation, which could be described as role-based ERPs. It could be asked whether this

Explicit local exchange-correlation potentials

The possibilities of the Hohenberg-Kohn-Sham local density theory are explored in view of recent advances in the theory of the interacting electron gas. The authors discuss and provide numerical data for the effective exchange-correlation potentials μxc for ground state problems and Vxc for excitation spectra. The potential μxc(r) is written as a factor β(ρ(r)), which depends on the local density

Subcellular localization of transforming growth factor-alpha in human eosinophil granulocytes

Eosinophils are involved in the inflammatory response seen in allergy and helminthic infestations. Eosinophils synthesize transforming growth factor-alpha (TGF-alpha), which may play a role in the development of the characteristic fibrosis seen in longstanding high eosinophilia. Using immunoelectron microscopic techniques, eosinophils from peripheral blood of healthy individuals and from one patie

Methods for Assessing Traffic Safety in Developing Countries

Every year about 15 million people are injured in traffic, 500,000 of these fatally. Developing countries are badly affected. During the worst years of the war in Nicaragua, more people died in traffic accidents than as a direct result of the war. Transport system and infrastructure have developed rapidly in developing countries, while little has been achieved in preventing accidents or lessening