Many novel pharmaceutically active substances are characterized by a high hydrophobicity and a low water solubility, which present challenges for their delivery as drugs. Tablets made from cross-linked hydrophobically modified poly (acrylic acid) (CLHMPAA), commercially available as Pemulen™, have previously shown promising abilities to control the release of hydrophobic model substances. This stu

This is a review of the hip arthroplasty era. We concentrate on new metal bearings, surface replacements, and the lessons not learned, and we highlight recent reports on malignancies and joint implants. A low incidence of blood malignancies has been found in bone marrow taken at prosthetic surgery. The incidence is increased after replacement with knee implants that release very low systemic level

I det moderna samhället är en välplanerad infrastruktur med fungerande transporter och pendling en självklarhet. Transportsystemet har inverkan på fysisk och social miljö och det finns ett stort behov av att minska de negativa effekterna. Förutom tillgänglighet och minskad miljöpåverkan betonas ofta vikten av kostnadseffektivitet. Denna rapport beskriver ett verktyg framtaget inom ramen för HASTA

The last decades of the 10th century saw an upheaval in interregional contacts that shattered old arrangements. Some of the nodes in the network were abandoned. Sigtuna seems to be established in the wake of Birka’s demise, but it took two or three decades before foreign guests found their way on a regular basis. With the structural pre-millennium re-arrangement, negotiations with both Continental

The aims of this thesis where the target population has been older adults suffering from osteoporosis related fractures were firstly to study the association between functional impairment due to pain, and activity expressed as walking speed (WS) and Timed Get up and-Go (TUG), and to examine the associations between functional impairment and social participation (SP) and quality of life (QoL). Seco

The intermetallic compound AuSn is essential for the wetting of Au-rich AuSn solders. On the addition of In or Sb, pseudo-binary compounds AuSn1-x In (x) (x a parts per thousand currency sign 0.33) and AuSn1-y Sb (y) (y a parts per thousand currency sign 0.17) are formed. Both adopt the AuSn structure type (P6(3)/mmc, Z = 2). This single-crystal X-ray diffraction study reveals that there is an abs

Experience with crash prediction modeling has confirmed the importance of traffic volume, not only as exposure but also as a predictive variable. For intersection-related collisions, for example, angle collisions or any collisions involving turning vehicles, traffic volumes on both intersecting roads are necessary for sufficient prediction of crash count These collisions occur not only at intersec

We propose new M-algorithm BCJR (M-BCJR) algorithms for low-complexity turbo equalization and apply them to severe intersymbol interference (ISI) introduced by faster than Nyquist signaling. These reduced-search detectors are evaluated in simple detection over the ISI channel and in iterative decoding of coded FTN transmissions. In the second case, accurate log likelihood ratios are essential and

The dynamic ecosystem model LPJ-GUESS combines sophisticated plant physiological and biogeochemical processes and has been successfully used in predicting vegetation dynamics at different scales. However, the water cycling is limited to vertical water movement between the atmosphere plant-soil. Thus we have developed an enhanced version of LPJ-GUESS (called LPJ-DH) by coupling water routing and la

I report that a 75-year-old man with severe atherosclerosis experienced two episodes of bacteremia with Streptococcus pyogenes of type emm87. Recurrent sepsis with S. pyogenes is extremely rare, and a foot ulcer was the suspected point of entry. The patient did not develop opsonizing antibodies to the isolate.

Objective:To assess the importance of MAPT variant p.A152T in the risk of synucleinopathies. Methods:In this case-control study, we screened a large global series of patients and controls, and assessed associations between p.A152T and disease risk. We included 3,229 patients with clinical Parkinson disease (PD), 442 with clinical dementia with Lewy bodies (DLB), 181 with multiple system atrophy (M

ISHP (Ion Source Hydrogen Positive) project consists of a highly versatile ECR type ion source. It has been built for several purposes, on the one hand, to serve as a workbench to test accelerator related technologies and validate in-house made developments, at the first stages. On the other hand, to design an ion source valid as the first step in an actual LINAC. Since this paper is focused on th

First, we explore the performance of nonword repetition (NWR) in children with specific language impairment (SLI) and typically developing children (TD) in order to investigate the accuracy of NWR as a clinical marker for SLI in Swedishspeaking school-age children. Second, we examine the relationship between NWR, family aggregation, and parental level of education in children with SLI. A sample of

The present study aimed to evaluate the frequency of warning signs in younger patients with stroke with a special regard to the 'FAST' scheme, a public stroke recognition instrument (face, arm, speech, timely).

Purpose - An important task following international acquisitions is to coordinate customer relationships; that is, to organise customer interfaces and possibly establish new relationships between customers and the acquirer/the acquired party. Yet, such coordination may prove to be problematic, not the least since customers react to acquisitions. The purpose of this paper is to describe and discuss

This study explores the global regulative function of migration politics. Its main aim is to rethink migration politics through an engagement with the Foucauldian governmentality perspective, which focuses on the relation between government and thought. A secondary aim is to use this perspective to explore the global description of migration and migration politics which is emerging with the curren

A wireless body area network (WBAN) is a network of compact low power devices that are either wearable or implantable. A compact antenna with suitable radiation pattern and polarization is useful for WBAN applications. Ultra-Wideband (UWB) technology can be used in WBAN applications that require high data rates. This paper present a small wearable (15x17x17 mm) UWB antenna designed and optimized i

1. Thousands of lakes in the Northern Hemisphere are experiencing a continuous increase in water temperature and colour. While increasing temperature is an effect of climate change, several factors are suggested to drive the increasing water colour, including climate change, altered land use and reversed acidification. 2. In this mesocosm study, we study the effects on pelagic production and sedim

Objectives: To assess satisfaction with life as a whole and 10 domains of life satisfaction in Swedish individuals after a traumatic brain injury, to describe the relationship with demographic, social and injury related variables, and to compare the level of life satisfaction with a Swedish reference sample. Subjects: Fifty-one men and sixteen women, 6-15 years after a traumatic brain injury. Meth