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Individual Patient Data Meta-analysis of Discrimination of the Four Kallikrein Panel Associated With the Inclusion of Prostate Volume

Objective: To assess whether adding prostate volume to the kallikrein panel improves discrimination for ISUP Grade Group 2 or higher (GG2+) disease, as some men may have volume measurements available at the time of blood draw. While prostate volume predicts biopsy outcome, it requires an imaging procedure for measurement. The four kallikrein panel - commercially available as the 4Kscore - predicts

Gardens’ contribution to people and urban green space

Cities are experiencing numerous challenges, adversely affecting human health and wellbeing. Urban green space provides ecosystem services that are important to meet urban challenges. One type of urban green space is private gardens (yards) that make up an essential part of many urban areas. Gardens can support urban biodiversity and provide cultural ecosystem services (CES) to its owner. However,

Analysis of extracorporeal photopheresis within the frame of the WAA register

The aim of the study was to investigate safety and if extracorporeal photopheresis (ECP) may change health criteria (HC) and quality of life (QoL). Material and method: 560 patients (33 % women) were treated with ECP for a total of 13,871 procedures during a 17-years period. Mean age was 48 years (±18, range 3−81 years). Self-estimation of QoL was graded: 0 (suicidal) up to 10 (best ever) and HC:

Speaking of business ethics: Bourdieu and market morality as a discursive practice

While communication of business ethics has increased in importance, it is often understood as being more of immaterial than material value. However, recent studies have demonstrated that language and communication can have important social consequences, changing institutional logics and daily practices in economic fields. This conceptual paper explores how sociologist Pierre Bourdieu’s theory of p

Death of a Genre? : The Aesopic Fable and the Emergence of Modernity

Taking as its starting point the scholarly discussion about the possible death of the Aesopic fable towards the end of the eighteenth century, this article proposes a broadening of perspective, arguing for a thorough examination of the impact of modernity on some of the basic contexts and conditions of the genre. Four contextual factors are, subsequently, placed under scrutiny: the ethics of virtuTaking as its starting point the scholarly discussion about the possible death of the Aesopic fable towards the end of the eighteenth century, this article proposes a broadening of perspective, arguing for a thorough examination of the impact of modernity on some of the basic contexts and conditions of the genre. Four contextual factors are, subsequently, placed under scrutiny: the ethics of virtu

Flow cytometric analysis reveals culture-condition dependent variations in phenotypic heterogeneity of Limosilactobacillus reuteri

Industrial production of probiotic bacteria must be adapted to reach a stable product with resistance to unfavourable environmental conditions during storage and that display probiotic functionality. Flow cytometry-based descriptors, light scatter and pulse width of bacterial morphology were used as markers to estimate physiological fitness. The effects of temperature, pH and oxygen levels on cell

Flow cytometric analysis reveals culture condition dependent variations in phenotypic heterogeneity of Limosilactobacillus reuteri

Optimisation of cultivation conditions in the industrial production of probiotics is crucial to reach a high-quality product with retained probiotic functionality. Flow cytometry-based descriptors of bacterial morphology may be used as markers to estimate physiological fitness during cultivation, and can be applied for online monitoring to avoid suboptimal growth. In the current study, the effects

Moving beyond intermediation : How intermediary organizations shape collaboration dynamics in entrepreneurial ecosystems

Recently, increasing attention has been paid to entrepreneurial ecosystems and the process of their formation and function. Researchers have noted the important role that intermediary organizations such as incubators play in connecting various actors within ecosystems. Yet our understanding of this role is limited to a few empirical insights. Using resource dependence and embeddedness as theoretic

The simulation of wildland-urban interface fire evacuation : The WUI-NITY platform

Wildfires are a significant safety risk to populations adjacent to wildland areas, known as the wildland-urban interface (WUI). This paper introduces a modelling platform called WUI-NITY. The platform is built on the Unity3D game engine and simulates and visualises human behaviour and wildfire spread during an evacuation of WUI communities. The purpose of this platform is to enhance the situationa

Evacuation behaviors and emergency communications : An analysis of real-world incident videos

Emergencies such as fires and terrorist attacks pose risks of injuries and fatalities, which can be exacerbated by delayed, ill-informed, or unmanaged responses. Effective emergency communication strategies could be used to better inform people and reduce these risks. This research analyzes videos of real-world emergencies to: (a) identify people's observed behaviors that increase risk during evac

Pharyngotonsillitis in primary health care. Aetiology and clinical findings.

Faryngotonsillit, eller halsfluss, är en vanlig orsak till att patienter söker primär-vård och är även en vanlig orsak till antibiotikaförskrivning. Bakterien Grupp A-streptokocker (GAS) har sedan länge varit den viktigaste mikroorganismen vid halsfluss, inte minst på grund av dess koppling till följdsjukdomar som exempelvis reumatisk hjärtsjukdom, men det finns många andra bakterier och virus somPharyngotonsillitis, or acute sore throat, is a common reason for attending primary health care and a common reason for antibiotic prescription. Group A Streptococcus (GAS) has long been considered the most important pathogen in pharyngotonsillitis, but a wide array of other bacteria and viruses have also been associated with this condition. However, few studies have used modern approaches for aet

Where drills differ from evacuations : A case study on Canadian buildings

Planned egress drills are required by building codes around the world, and are commonly used to both train occupants and assess evacuation procedures. However, capturing the idea of a “successful” drill is often difficult. Data from both drills and unplanned evacuations are often incomplete and unreliable, which raises a key question: How well-matched are planned egress drills and unplanned evacua

How can businesses drive sufficiency? The business for sufficiency framework

The breaching of planetary boundaries and excessive extraction of natural resources requires a revisited approach to consumption and production. The concept of sufficiency, which advocates meeting human needs within the planetary limits by curbing excessive consumption levels, is gaining increasing attention. Businesses are drivers of consumption, yet they have been largely overlooked as potential