The aim of the thesis is to evaluate solutions to the class imbalance problem using real world data sets with varying degrees of class imbalance. The analysis is limited to binary classification. Three large data sets relating to credit card fraud, vehicle insurance and heart disease are used for the analysis. Several methods are compared and evaluated. Logistic regression, SVC and decision trees

Cobalt-containing nanoparticles have been prepared via thermal decomposition of cobalt acetate on the surface of poly(tetrafluoroethylene) (PTFE) microgranules forming a fluidized bed over the surface of hot mineral oil. Using transmission electron microscopy, the average size of the cobalt-containing nanoparticles has been determined to be 3.6 nm. The composition and structure of the nanoparticle

We utilize data from the Survey of Health, Ageing and Retirement in Europe (SHARE) 1 to investigate the impact of retirement on mental health in a multi-country setting. To deal with endogeneity in retirement behaviour, we employ an individual-fixed effects IV strategy where pension eligibility thresholds at which financial incentives to retire are exploited to predict retirement behaviour. The co

System level synthesis is a promising approach that formulates structured optimal controller synthesis problems as convex problems. This work solves the distributed linear-quadratic regulator problem under communication constraints directly in infinite-dimensional space, without the finite-impulse response relaxation common in related work. Our method can also be used to construct optimal distribu

We developed a process for enzyme-linked immunosorbent assay on a glass microchip via the use of a thin-layered microfluidic channel. This channel possesses a high aspect ratio (width/depth ∼200) and has an antibody layer immobilized directly on the channel surface. A depth of several microns and an excessive width and length (mm scale) of the channel provide a large-volume capacity (102 nL) and m

We present property probes, a mechanism for helping a developer interactively explore partial program analysis results in terms of the source program, and as the program is edited. A node locator data structure is introduced that maps between source code spans and program representation nodes, and that helps identify probed nodes in a robust way, after modifications to the source code. We have dev

Background: Clinical Impression of Severity Index for Parkinson's Disease (CISI-PD) is a simple tool that can easily be used in clinical practice. Few studies have investigated the relationship between health-related quality of life and the CISI-PD. Objective: To analyze the association of CISI-PD scores with those of generic (EQ-5D-5L) and Parkinson's disease (PD) disease-specific (Parkinson's Di

The design of an adaptive controller with bounded L2-gain from disturbances to errors for linear time-invariant systems with uncertain parameters restricted to a finite set is investigated. The synthesis of the controller requires finding matrices satisfying non-convex matrix inequalities. We propose an approach for finding these matrices based on repeatedly linearizing the terms that cause the no

We study network SIR (Susceptible - Infected - Recovered) epidemic models in the case of two interacting populations. We analyze the dynamics behavior of the fractions of infected individuals in the two populations. In contrast to the classical scalar SIR epidemic model, where the fraction of infected individuals is known to have an unimodal behavior (either decreasing throughout time or initially

Cerium oxide nanoparticles modified montmorillonite was obtained by interaction of a clay with (NH4)2Ce(NO3)6. The mean size of cerium oxide nanoparticles in clay was at 3.5 nm. The product was an amorphous solid and showed high permanent porosity and stability at high temperatures. The amorphous structure of the sample was proven by X-ray diffraction and electronic diffraction. The porous structu

Synthesis of nanocomposites based on the low density polyethylene (LDPE) with homogeneous dispersion of CeO2 nanoparticles is reported.

In this paper, we report the discovery of TOI-220 b, a new sub-Neptune detected by the Transiting Exoplanet Survey Satellite (TESS) and confirmed by radial velocity follow-up observations with the HARPS spectrograph. Based on the combined analysis of TESS transit photometry and high precision radial velocity measurements, we estimate a planetary mass of 13.8 ± 1.0 M⊕ and radius of 3.03 ± 0.15 R⊕,

Cancer is a disease affecting many people where a possible treatment is immunotherapy. Immunotherapy has possible side effects called immune-related adverse events (irAEs) where cytokine release syndrome (CRS) is one. CRS differs in severity and an increased amount of cytokines are secreted. In this project, the aim was to explore key events of irAEs and to develop an assay to predict CRS. The eff

Giant cell arteritis (GCA), the most common non-infectious vasculitis, mainly affects elderly individuals. The disease usually affects the aorta and its main supra-aortic branches causing both general symptoms of inflammation and specific ischemic symptoms because of the limited blood flow due to arterial structural changes in the inflamed arteries. The pathogenesis of the GCA is complex and inclu

Background: Sexual harassment (SH) in the workplace is prevalent and associated with poor health. Universities are large workplaces with complex formal and informal power relations, which may influence the prevalence of SH. Although employees and students share the university context, few studies on SH have included both groups. The overall aim of the study was to investigate SH among employees an