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Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow

Formation of the hematopoietic stem cell (HSC) niche in bone marrow (BM) is tightly associated with endochondral ossification, but little is known about the mechanisms involved. We used the oc/oc mouse, a mouse model with impaired endochondral ossification caused by a loss of osteoclast (OCL) activity, to investigate the role of osteoblasts (OBLs) and OCLs in the HSC niche formation. The absence o

Social Ontology and Social Cognition

The aim of this paper is to show that there is a reciprocal dependency relationship between social cognition and social ontology. It is argued that, on the one hand, the existence conditions of socially meaningful objects and of social groups are about subjects’ social cognitive processes and interactive patterns and, on the other hand, social cognitive processes and interactive patterns are modul

Högskolepedagogik som motstånd och anpassning i historia, nutid och framtid

Denna artikel är en reflektion över högskolepedagogikens historia, nutid och framtid. I den identifieras två strategier som kan ses som syftet med en högskolepedagogisk utbildning för universitetslärare: motstånd mot negativa konsekvenser av den oerhörda förändring som skett av universiteten de senaste decennierna, samt anpassning till en överlevnad och sökandet efter styrka i dessa förändringar.

Optimal shape of a cold-neutron triple-axis spectrometer

We have performed a McStas optimization of the primary spectrometer for a generic 40 m long, cold-neutron triple-axis spectrometer with a doubly focusing monochromator. The optimal design contains an elliptically focusing guide, a virtual source point before a low-grade PG monochromator, and non-equidistant focusing at the monochromator. The flux at 5 meV shows a gain factor 12 over the "classical

Time perspective and mental health continuum: What are the time perspective profiles of flourishing, moderately mentally healthy, and languishing individuals?

Time perspective (TP) refers to individuals’ ways of constructing, reconstructing, and relating the psychological concepts of past, present,and future, and provides individuals with a coherence of experiences over time. In the present study, the relationships among five TPs (past negative, past positive, present fatalistic, present hedonistic, and future) were studied in a student sample (N = 280)

Replication of genomewide associations with allergic sensitization And allergic rhinitis

Background: Three genomewide metastudies have recently reported associations with self-reported allergic rhinitis and allergic sensitization. The three studies together identified a set of 37 loci but showed low concordance. This study investigates the reproducibility of the detected single nucleotide polymorphism (SNP) associations in an extensively characterized longitudinal cohort, BAMSE. Metho

Two-particle Bose-Einstein correlations in pp collisions at [Formula: see text] 0.9 and 7 TeV measured with the ATLAS detector.

The paper presents studies of Bose-Einstein Correlations (BEC) for pairs of like-sign charged particles measured in the kinematic range [Formula: see text] 100 MeV and [Formula: see text] 2.5 in proton collisions at centre-of-mass energies of 0.9 and 7 TeV with the ATLAS detector at the CERN Large Hadron Collider. The integrated luminosities are approximately 7 [Formula: see text]b[Formula: see te

No title

This is an announcement for the networks "Choir in Focus" - funded by Riksbankens Jubileumsfond - second network meeting at Chor.Com in Dortmund September 2011.

Evaluation of Interactive Voice Response (IVR) and postal survey in follow-up of children and adolescents discharged from psychiatric outpatient treatment: a randomized controlled trial.

Systematic evaluation of child and adolescent psychiatric outpatient treatment is important but time-consuming. The aim of this paper was to study whether Interactive Voice Response (IVR) is a more effective method than a questionnaire sent by post when following up outpatient treatment in child and adolescent psychiatry. Eighty patients were recruited from a child and adolescent psychiatric outpa

The Association Between Hyperglycemia and Fracture Risk in Middle Age. A prospective, population-based study of 22 444 men and 10 902 women.

Aims: Type 1 diabetes mellitus is associated with increased fracture risk, whereas the risk associated with type 2 diabetes is less obvious. Elevated fasting blood glucose (FBG) and high 2-hour glucose during an oral glucose tolerance test (OGTT) indicate impaired glucose tolerance or diabetes. The associations between FBG, 2-h glucose and the risk of fracture were investigated. Methods: The Malmö

Survival in amoeba-a major selection pressure on the presence of bacterial copper and zinc resistance determinants? Identification of a "copper pathogenicity island"

The presence of metal resistance determinants in bacteria usually is attributed to geological or anthropogenic metal contamination in different environments or associated with the use of antimicrobial metals in human healthcare or in agriculture. While this is certainly true, we hypothesize that protozoan predation and macrophage killing are also responsible for selection of copper/zinc resistance

Models and Methods for Random Fields in Spatial Statistics with Computational Efficiency from Markov Properties

Popular Abstract in Swedish Beräkningsmässigt skalar många av de klassiska metoderna inom spatiell statistik kubiskt med antalet observationer, vilket är opraktiskt om datamängderna är stora. I de traditionella tillämpningarna av statistik på spatiella datamänger begränsades ofta antalet observationer på grund av höga mätkostnader och metodernas beräkningskomplexitet inte sällan ett problem. NumerThe focus of this work is on the development of new random field models and methods suitable for the analysis of large environmental data sets. A large part is devoted to a number of extensions to the newly proposed Stochastic Partial Differential Equation (SPDE) approach for representing Gaussian fields using Gaussian Markov Random Fields (GMRFs). The method is based on that Gaussian Matérn fie

A Biomechanical Assessment of Repair Versus Nonrepair of Sheep Flexor Tendons Lacerated to 75 Percent

Purpose The benefit of repairing a 75% partial flexor tendon laceration remains controversial. The purpose of this study was to assess the degree of gap formation with and without repair when the 75% lacerated tendon is subjected to cyclic loading. Repair with only a peripheral suture was compared to that using a core and peripheral repair technique. Methods Sixteen deep flexor tendons from sheep

Terrestrial export of highly bioavailable carbon from small boreal catchments in spring floods

1. We assessed the terrestrial export of organic carbon, which effectively supported aquatic bacterial production (BP), from small boreal catchments during spring flood. We analysed stream runoff from nine small catchments with different proportions of peat mires and coniferous forests by monitoring the dissolved organic carbon (DOC) flux in combination with conducting bacterial bioassays. 2. Mu

A compact six-port dielectric resonator antenna array: MIMO channel measurements and performance analysis

MIMO systems ideally achieve linear capacity gain proportional to the number of antennas. However, the compactness of terminal devices limits the number of spatial degrees of freedom (DOFs) in such systems, which motivates efficientantenna design techniques to exploit all available DOFs. In this contribution, we present a compact six-port dielectric resonator antenna (DRA) array which utilizes spa

Time use among individuals with persistent mental illness: Identifying risk factors for imbalance in daily activities

The aim of this study was to investigate associations between time use in daily activities and sociodemographic and clinical factors in order to identify individuals with persistent mental illness at risk of having an imbalance in daily activities, as reflected in their time use and daily rhythm. Participants (n=103) were selected from a psychiatric outpatient unit using a randomized stratified se

Prevalence of spondyloarthritis and its subtypes in southern Sweden

OBJECTIVE: To estimate the prevalence of spondyloarthritis and its subtypes. METHODS: The Swedish healthcare organisation comprises a system where all inpatient and outpatient care is registered by a personal identifier. For the calendar years 2003-7, all residents aged ≥15 years in the southernmost county of Sweden (1.2 million inhabitants) diagnosed by a physician with spondyloarthritis (ankylo

The Value of Intimacy - Negotiating Commercial Friendship in Lifestyle Entrepreneurship

With the aim to reconsider lifestyle values in relation to economic rationality in small tourism and hospitality businesses, we focus on the “commercial home” as a site where boundaries between personal and commercial values are constantly performed in practice. Through an interactionist analysis of the narrative of a B&B and gallery owner, we illustrate the emergence of intimacy as a commerci