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Our boy Whitey : Middle-aged women’s happy object on TikTok

Den här artikeln ger ett exempel på hur medelålders kvinnor återupptäcker och uttrycker känslor i digitala medier, främst sexuell åtrå men också den glädje de känner bland likasinnade kvinnor i samma ålder. Det etnografiska exemplet är en grupp europeiska och nordamerikanska kvinnor i åldrarna 40-60 år som känner sexuell åtrå till den 20-årige TikTok-kändisen William White. White blev viral när haThis article provides an example of how middle-aged women rediscover and express emotions in digital media, mainly sexual desire but also the joy they feel among like-minded women of the same age. The ethnographic case is a community of European and North American women aged around 40 to 60 years who sexually desire 20-year-old TikTok celebrity William White. White went viral when he began lip-syn

Samtycke till provrörsbefruktning

Poddcast "Öppet fall" från Lunds universitet, Juridiska fakulteten: Ett gift par som inte kan få egna barn beger sig till en fertilitetsklinik för att göra en provrörsbefruktning. Kvinnan vill sätta in två ägg men mannen går bara med på ett ägg. Trots det säger hon till kliniken att sätta in två ägg och blir gravid med tvillingar. Mannen accepterar inte att bli pappa till barnen eftersom han inte

Superporous Agarose Gels: Production, Properties, and Applications

Agarose is a well-established material in many applications of biochemistry and biotechnology. Agarose gels are used for electrophoresis of very large molecules such as DNA and agarose-based particles are used as chromatographic media for separation of all sorts of biomolecules, particularly proteins. Prominent commercial examples of agarose-based separation particles are exemplied by the brand na

Left Ventricular Diastolic Function in Children with Atrial Septal Defects Improves After Closure by Means of Increased Hydraulic Force.

Hydraulic force aids diastolic filling of the left ventricle (LV) by facilitating basal movement of the atrioventricular plane. The short-axis atrioventricular area difference (AVAD) determines direction and magnitude of this force. Patients with atrial septal defect (ASD) have reduced LV filling due to the left-to-right shunt across the atrial septum and thus potentially altered hydraulic force.

Technocultural worldings: dialectical dynamics in contemporary media landscapes

In this piece, which frames the special issue “Technocultural worldings,” we build on previous editions of commentary and criticism in this journal. We propose a theoretically anchored way to systematically approach the dynamic, multidimensional, and heterogeneous technocultural communities that have created their own worldings and are engaged in complex dialectical dynamics within the contemporar

Atrial septal defect closure in children at young age is beneficial for left ventricular function.

AimsAtrial septal defects (ASDs) lead to volume-loaded right ventricles (RVs). ASD closure does not always alleviate symptoms or improve exercise capacity, which is possibly explained by impaired left ventricular (LV) haemodynamics. This study evaluated the effect of ASD closure in children using non-invasive LV pressure–volume (PV) loops derived from cardiac magnetic resonance (CMR) imaging and b

Respect and anxiety : Guns as ambiguous symbols for criminally involved youth in Sweden

Youth gun violence has surged in Sweden recently. Quantitative studies have described the prevalence and geographical locations of gun violence, but little research has examined how perpetrators and victims themselves experience and make sense of guns. This article draws on ethnographic interviews with young men who have firsthand experience of gun violence in a criminal context. Drawing on narrat

Som spridda sädeskornen : Perspektiv på nattvardens levda teologi

I många av Svenska kyrkans församlingar firas mässa en eller flera gånger i veckan. Nattvarden är i högsta grad både aktuell och angelägen - och den engagerar. Med anledning av en ny kyrkohandbok 2017 och ett biskopsbrev om nattvarden 2020 har såväl gamla som nya frågor väckts, och diskussionen om nattvarden har intensifierats. Inte minst har förhållandet mellan teologin i de normativa dokumenten

CysK2 from Mycobacterium tuberculosis is an O-phospho-L-serine-dependent S-sulfocysteine synthase

Mycobacterium tuberculosis is dependent on cysteine biosynthesis, and reduced sulfur compounds such as mycothiol synthesized from cysteine serve in first-line defense mechanisms against oxidative stress imposed by macrophages. Two biosynthetic routes to L-cysteine, each with its own specific cysteine synthase (CysK1 and CysM), have been described in M. tuberculosis, but the function of a third put

Structure of LdtMt2, an l,d-transpeptidase from Mycobacterium tuberculosis

The transpeptidase LtdMt2 catalyzes the formation of the (3-3) cross-links characteristic of the peptidoglycan layer in the Mycobacterium tuberculosis cell wall. Bioinformatics analysis suggests that the extramembrane part of the enzyme consists of three domains: two smaller domains (denoted as A and B domains) and a transpeptidase domain (the C domain) at the C-terminus. The crystal structures of

N-Thio-β-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis

Effective treatment of tuberculosis is frequently hindered by the emerging antimicrobial resistance of Mycobacterium tuberculosis. The present study evaluates monocyclic β-lactam compounds targeting the mycobacterial cell wall remodeling. Novel N-thio-β-lactams were designed, synthesized, and characterized on the L,D-transpeptidase-2, a validated target in M. tuberculosis. The candidates were eval

The structure of the N-terminal module of the cell wall hydrolase RipA and its role in regulating catalytic activity

RipA plays a vital role during cell division of Mycobacterium tuberculosis by degrading the cell wall peptidoglycan at the septum, allowing daughter cell separation. The peptidoglycan degrading activity relies on the NlpC/P60 domain, and as it is potentially harmful when deregulated, spatial and temporal control is necessary in this process. The N-terminal domain of RipA has been proposed to play

Binding and processing of β-lactam antibiotics by the transpeptidase LdtMt2 from Mycobacterium tuberculosis

β-lactam antibiotics represent a novel direction in the chemotherapy of tuberculosis that brings the peptidoglycan layer of the complex mycobacterial cell wall in focus as a therapeutic target. Peptidoglycan stability in Mycobacterium tuberculosis, especially during infection, relies on the nonconventional peptide cross-links formed by l,d-transpeptidases. These enzymes are known to be inhibited b

Long term sustained attention alters dynamic functional connectivity patterns

Mental fatigue has attracted much attention from researchers as it plays a key role in performance efficiency and safety situations. Functional connectivity analysis using graph theory is an effective method for revealing changes in cognition resources influenced by mental fatigue. Previous studies have revealed that functional networks are dynamically reorganized. Therefore, it is critical to exp

Isolation of nucleic acids using a polycationic polymer as precipitation agent

The present invention relates to a method of isolating a desired nucleic acid from a biological solution, which method comprises to selectively precipitate the desired nucleic acid by adding a polycationic precipitating agent to the solution and allowing it to form a complex with said nucleic acid, wherein the precipitating agent is a highly charged linear polymer that comprises quaternary amino g

Lectin-containing separation agent

A separation agent composed of a water unsoluble solid substance with a covalently bound lectin. Said solid substance is structurally composed of a water unsoluble silica or silicate material as basic material and, via a linkage to silicon atoms in the silica or silicate material, a covalently bound lectin.