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IL6 gene promoter polymorphisms and type 2 diabetes - Joint analysis of individual participants' data from 21 studies
Several lines of evidence indicate a causal role of the cytokine interleukin (IL)-6 in the development of type 2 diabetes in humans. Two common polymorphisms in the promoter of the IL-6 encoding gene IL6, -174G > C (rs1800795) and -573G > C (rs1800796), have been investigated for association with type 2 diabetes in numerous studies but with results that have been largely equivocal. To clarify the
Alcohol Intervention Studies in University Students. Randomised Controlled Trials of Responsible Beverage Service and High Risk Drinking.
The aim was to study implementation and efficacy of two intervention techniques for risky alcohol consumption in university students. One technique was the Responsible Beverage Service Programme modified for use in students pubs. The other was a cognitive-based education programme (10 hours) for freshman students with risky alcohol consumption that was compared with a mailed personalised drinking
Postmodern teologi
Artikeln ger en kort introduktion till postmodern teologi.
Vitamin K-dependent Gas6 activates ERK kinase and stimulates growth of cardiac fibroblasts.
Aktiv utrikespolitik : En jämförelse mellan svensk och dansk utrikesdebatt 1962-1978
Compact third-order multidimensional upwind discretization for steady and unsteady flow simulations
We propose a new third-order multidimensional upwind algorithm for the solution of the flow equations on tetrahedral cells unstructured grids. This algorithm has a compact stencil (cell-based computations) and uses a finite element idea when computing the residual over the cell to achieve its third-order (spatial) accuracy. The construction of the new scheme is presented. The asymptotic accuracy f
High transverse momentum eta meson production in p+p, d+Au, and Au+Au collisions at root s(NN)=200 GeV
Inclusive transverse momentum spectra of eta mesons in the range p(T)approximate to 2-12 GeV/c have been measured at midrapidity (vertical bar eta vertical bar < 0.35) by the PHENIX experiment at RHIC in p+p,d+Au, and Au+Au collisions at root s(NN)=200 GeV. The eta mesons are reconstructed through their eta ->gamma gamma channel for the three colliding systems as well as through the eta ->pi(0)pi(
Gråtens världar. Perspektiv på mäns tårar.
This study, based on interviews with army officers, focuses on crying as an action, creating meaning in our interpretation of the world. The discourse of male crying includes the image of a man wanting to express himself emotionally, but unable to because of the traditional ideal of self-control.
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The dUTPases from herpes simplex virus type 1 and mouse mammary tumour virus are less specific than the Escherichia coli enzyme
The enzyme dUTPase catalyses the hydrolysis of dUTP to dUMP and pyrophosphate, thereby suppressing incorporation of uracil into DNA and providing a pool of dUMP, the precursor of dTTP. Hydrolysis of other nucleotides similar in structure to dUTP would conceivably be physiologically detrimental and high specificity of the reaction seems to be necessary. In this work, we characterize the substrate s
Etik och känslor : en empirisk studie av skuld- och medkänslor hos gymnasieelever – en prövning av Ortonys teori
Popular Abstract in SwedishEn del av Ortonys teorimodell angående den kognitiva strukturen hos emotioner testades på svenska gymnasieelever. Den del av teorin som användes i föreliggande studie handlade om de emotioner som tillskrivs den som utfört s.k. orätta handlingar. De eventuella känslor som man får när man utfört en orätt handling kallar Ortony för "self reproach" emotioner. Detta begrepp sThe purpose of this study was to test parts of Ortony's theoretical model relating to the cognitive structure of emotions in Swedish upper secondary school students. That part of the model, which was appropriate for the present study, deals with emotions attributed to the person who has perpetrated what is referred to as blameworthy actions. Ortony calls the possible emotions that you experience w
Binding of monoclonal IgM rheumatoid factor to streptococci via the antibody combining site
Radiolabelled monoclonal IgM rheumatoid factors, four from patients with type II essential cryoglobulinaemia and one originating from a patient with rheumatoid arthritis, were tested for binding to group A, B, C and G streptococci and Escherichia coli. Two of the preparations exhibited different binding patterns for the streptococci, whereas the remaining three were not reactive. The binding of on
Cages in tandem: Management control, social identity, and identification in a knowledge-intensive firm
Developments in organization studies downplay the role of bureaucracy in favour of more flexible arrangements and forms of organizational control, including socio-ideological control. Corporate culture and regulated social identities are assumed to provide means for the integration and orchestration of work. Knowledge-intensive firms, which typically draw heavily upon socio-ideological modes of co
Basic science of peripheral nerve repair: Wallerian degeneration/growth cone
Trauma to a peripheral nerve trunk is a complex injury because it involves not only repair processes locally at the peripheral level, but it also engages repair and compensation mechanisms at central levels. The main actor is the fascinating and unique neuron with its supporting cells, which consist mainly of Schwann cells. In the neuron and in the Schwann cells, intracellular signaling mechanisms
Nonparametric estimation of mixing densities for discrete distributions
By a mixture density is meant a density of the form pi(mu) (.) = f pi(theta) (.) x mu(d theta), where (pi(theta))(theta Theta is an element of) is a family of probability densities and mu is a probability measure on Theta. We consider the problem of identifying the unknown part of this model, the mixing distribution A, from a finite sample of independent observations from pi(mu). Assuming that the
Predictive factors of developing diabetes mellitus in women with gestational diabetes.
BACKGROUND: To investigate which factors during gestational diabetes pregnancies correlate with the risk of developing impaired glucose tolerance or diabetes 1 year postpartum and to compare this risk in women with gestational diabetes and women with a normal oral glucose tolerance test during pregnancy. METHODS: Of 315 women with gestational diabetes, defined as a 2-hr blood glucose value of at l
Multipliers for Stability Analysis of Systems with Nonlinearities
Weak D type 2 is the most prevalent weak D type in Portugal
The weak D phenotype is the most common D variant, with a frequency of 0.2-1% in Caucasian individuals. There are several weak D types, with different frequencies in European countries, which may pose serologic problems and have the potential for alloimmunization. Samples from Portuguese individuals were tested for RhD by two or three distinct monoclonal and oligoclonal antisera, in direct aggluti
Influence of severe hypoglycemia on mitochondrial and plasma membrane function in rat brain
Abstract: Previous experiments have shown that severe hypoglycemia disrupts cerebral energy state in spite of a maintained cerebral oxygen consumption, suggesting uncoupling of oxidative phosphorylation. Other studies have demonstrated that hypoglycemia leads to loss of cerebral cortical phospholipids and phospholipid-bound fatty acids. The objective of the present study was, therefore, to study r
