AimDespite new therapies, castration-resistant prostate cancer (CRPC) is still incurable. Intercellular Adhesion Molecule 1 (ICAM-1) is a well-characterized cell surface protein involved in prostate cancer pathogenesis, differentially expressed during transition from hormone-sensitive to CRPC. This study aimed to investigate ICAM-1 as a target for imaging and radioimmunotherapy of CRPC.MethodsAntiDespite new therapies, castration-resistant prostate cancer (CRPC) is still incurable. Intercellular Adhesion Molecule 1 (ICAM-1) is a well-characterized cell surface protein involved in prostate cancer pathogenesis, differentially expressed during transition from hormone-sensitive to CRPC. This study aimed to investigate ICAM-1 as a target for imaging and radioimmunotherapy of CRPC.Anti-ICAM-1 an

As the support for households which bring up an infant is increasing recently, there is a growing concerning about the consistency of such support with applicable support system and a greater interest in the change of demands for infant-rearing support policy for those households. Therefore, systemization is necessary to identify various supports for infant-rearing families quickly and to provide

Over the past years, the natural environment has increasingly become instrumental in peace policies and the focus of study in peace and conflict research. Concurrently, there is mounting global recognition that nature contributes to peoples wellbeing in manifold ways and that incorporating diverse values of nature in policymaking is paramount for sustainable development. At the nexus of current de

Previous research has established that the brain uses episodic memories to make continuous predictions about the world and that prediction errors, so the mismatch between generated predictions and reality, can lead to memory updating. However, it remains unclear whether prediction errors can stimulate updating in memories for naturalistic conversations. Participants encoded naturalistic dialogues,

Background: As the deadline for the Sustainable Development Goals approaches, financial protection in Cambodia remains inadequate, especially for nonpoor informal workers lacking formal social health protection coverage or access to other prepayment schemes. This exposes them to high out-of-pocket health expenditures (OOPE) and related financial hardship. To better understand the drivers behind th

In 2022, the Yangtze River Basin in China experienced an unprecedented extreme drought, induced by high temperatures and precipitation deficits. Accurate monitoring of such extreme drought events is vitally significant for disaster mitigation under global warming. This study evaluated the effectiveness of two satellite-based precipitation products: the latest Integrated Multi-satellitE Retrievals

Aim of the workshop: We invite colleagues to share experiences on cross-fertilization of art and social work research and to discuss how research-based art can serve as a catalyst for social change. Also, the workshop will give hands on knowledge on how to work with the method “deepened film talks”. Background: In a research project focusing moral stress and moral agency in social work, concrete s

Background and aims: Good Selenium (Se) status predicts favorable prognoses for various diseases and a reduced overall mortality. The primary objective of the study was to determine whether Selenium status, i.e. Selenoprotein P (SeP) levels, is associated with risk of 90-day mortality in elderly patients with acute dyspnea at the Emergency Department (ED). Methods and results: Patients presenting

In the policy discourse on societal challenges, it has become common to think of innovation policy as a key tool for addressing societal challenges. However, we argue that innovation policy has limits to what it can do, and for it to remain a useful tool for tackling societal challenges, it is necessary to re-assess its role. Thus, this paper addresses the following research questions: To what ext

The present paper establishes a simulation framework for modelling the deposition and solidification of steel melt in Directed Energy Deposition with a Laser Beam (DED-LB) by using the Particle Finite Element Method (PFEM). Unlike traditional finite element methods, the remeshing framework makes it possible to resolve the interaction between molten metal and substrate upon deposition, solidificati

Background: Osteoarthritis (OA) often leads to pain and functional limitations, impacting work and daily life. Physical activity (PA) is an important part of the treatment. Wearable activity trackers (WATs) offer a novel approach to promote PA but could also aid in finding a sustainable PA level over time. The aim of this secondary analysis was to examine the effects of self-monitoring PA with a W

PURPOSE: Dynamic glucose enhanced (DGE) MRI studies employ CEST or spin lock (CESL) to study glucose uptake. Currently, these methods are hampered by low effect size and sensitivity to motion. To overcome this, we propose to utilize exchange-based linewidth (LW) broadening of the direct water saturation (DS) curve of the water saturation spectrum (Z-spectrum) during and after glucose infusion (DS-

Network coherence generally refers to the emergence of simple aggregated dynamical behaviors, despite heterogeneity in the dynamics of the subsystems that constitute the network. In this paper, we develop a general frequency domain framework to analyze and quantify the level of network coherence that a system exhibits by relating coherence with a low-rank property of the system's input–output resp

Today's petrochemical industry relies on fossil hydrocarbons, not only for energy purposes but also as feedstock. This use of fossil materials is being challenged by the European Union's target to achieve climate neutrality by 2050. The most affected region in Europe is the cross-border region between Antwerp, Rotterdam and the Rhine-Ruhr area in western Germany, an interconnected petrochemical me

Current standard wound care involves dressings that provide moisture and protection; however, dressings providing active healing are still scarce and expensive. We aimed to develop an ecologically sustainable 3D printed bioactive hydrogel-based topical wound dressing targeting healing of hard-to-heal wounds, such as chronic or burn wounds, which are low on exudate. To this end, we developed a form

In this study, a literature review was conducted to identify indicators that can be utilised to assess and visualise the potential of the geophysical environment to deliver geosystem services. The literature review identified 24 studies and 22 technical reports, resulting in a list of 75 geosystem services indicators for 23 geosystem services associated with the subsurface. Building upon these fin