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β-Sarcoglycan Deficiency Reduces Atherosclerotic Plaque Development in ApoE-Null Mice

Background: Smooth muscle cells are important for atheroscleroticplaque stability. Their proper ability to communicatewith the extracellular matrix is crucial for maintainingthe correct tissue integrity. In this study, we have investigatedthe role of β-sarcoglycan within the matrix-binding dystrophin-glycoproteincomplex in the development of atherosclerosis.Results: Atherosclerotic plaque developm

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This study attempted to give a vision through which we can analyze narrative texts in artistic way bearing in mind their internal production conditions in addition to transformation trait which is related existentially to textual transformation. This is why it is called so. Thus textual transformation includes smaller transformations starting from the surface structure of the text, the place, the

Impact of Ph.D. training: a comprehensive analysis based on a Japanese national doctoral survey

Ph.D. training in academic labs offers the foundation for the production of knowledge workers, indispensable for the modern knowledge-based society. Nonetheless, our understanding on Ph.D. training has been insufficient due to limited access to the inside of academic labs. Furthermore, early careers of Ph.D. graduates are often difficult to follow, which makes the evaluation of training effects ch

Burden of cancer in the Eastern Mediterranean Region, 2005-2015 : findings from the Global Burden of Disease 2015 Study

OBJECTIVES: To estimate incidence, mortality, and disability-adjusted life years (DALYs) caused by cancer in the Eastern Mediterranean Region (EMR) between 2005 and 2015.METHODS: Vital registration system and cancer registry data from the EMR region were analyzed for 29 cancer groups in 22 EMR countries using the Global Burden of Disease Study 2015 methodology.RESULTS: In 2015, cancer was responsi

Transport injuries and deaths in the Eastern Mediterranean Region : findings from the Global Burden of Disease 2015 Study

OBJECTIVES: Transport injuries (TI) are ranked as one of the leading causes of death, disability, and property loss worldwide. This paper provides an overview of the burden of TI in the Eastern Mediterranean Region (EMR) by age and sex from 1990 to 2015.METHODS: Transport injuries mortality in the EMR was estimated using the Global Burden of Disease mortality database, with corrections for ill-def

Adolescent health in the Eastern Mediterranean Region : findings from the global burden of disease 2015 study

OBJECTIVES: The 22 countries of the East Mediterranean Region (EMR) have large populations of adolescents aged 10-24 years. These adolescents are central to assuring the health, development, and peace of this region. We described their health needs.METHODS: Using data from the Global Burden of Disease Study 2015 (GBD 2015), we report the leading causes of mortality and morbidity for adolescents in

Maternal mortality and morbidity burden in the Eastern Mediterranean Region : findings from the Global Burden of Disease 2015 study

OBJECTIVES: Assessing the burden of maternal mortality is important for tracking progress and identifying public health gaps. This paper provides an overview of the burden of maternal mortality in the Eastern Mediterranean Region (EMR) by underlying cause and age from 1990 to 2015.METHODS: We used the results of the Global Burden of Disease 2015 study to explore maternal mortality in the EMR count

Intentional injuries in the Eastern Mediterranean Region, 1990-2015 : findings from the Global Burden of Disease 2015 study

OBJECTIVES: We used GBD 2015 findings to measure the burden of intentional injuries in the Eastern Mediterranean Region (EMR) between 1990 and 2015.METHODS: The Global Burden of Disease (GBD) study defines intentional injuries as a combination of self-harm (including suicide), interpersonal violence, collective violence (war), and legal intervention. We estimated number of deaths, years of life lo