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Ciprofloxacin intercalated in fluorohectorite clay : Identical pure drug activity and toxicity with higher adsorption and controlled release rate

Different natural clay minerals, including halloysite, montmorillonite and kaolinite, have been proven to be efficient drug carriers providing for high and long lasting drug concentrations owing to their adsorption capacity and ion exchange property. Synthetic clays, however, are advantageous over the natural clay minerals in terms of purity of composition and controllable cation exchange capacity

Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation

The localization of glucokinase in pancreatic beta-cell nuclei is a controversial issue. Although previous reports suggest such a localization, the mechanism for its import has so far not been identified. Using immunofluorescence, subcellular fractionation and mass spectrometry, we present evidence in support of glucokinase localization in beta-cell nuclei of human and mouse pancreatic sections, a

Competition between influenza A virus subtypes through heterosubtypic immunity modulates re-infection and antibody dynamics in the mallard duck

Our overall hypothesis is that host population immunity directed at multiple antigens will influence the prevalence, diversity and evolution of influenza A virus (IAV) in avian populations where the vast subtype diversity is maintained. To investigate how initial infection influences the outcome of later infections with homologous or heterologous IAV subtypes and how viruses interact through host

High-photovoltage all-polymer solar cells based on a diketopyrrolopyrrole-isoindigo acceptor polymer

In this work, we synthesized and characterized two new n-type polymers PTDPP-PyDPP and PIID-PyDPP. The former polymer is composed of pyridine-flanked diketopyrrolopyrrole (PyDPP) and thiophene-flanked diketopyrrolopyrrole (TDPP). The latter polymer consists of PyDPP and isoindigo (IID). PIID-PyDPP exhibits a much higher absorption coefficient compared to the widely used naphthalene diimide (NDI)-b

Roadmap and roadblocks for the band gap tunability of metal halide perovskites

Solar cells based on metal-halide perovskite semiconductors inspire high hopes for efficient low cost solar cell technology. This material class exhibits a facile tunability of the band gap making them interesting for multi-junction device technology. We here compare and highlight trends in the band gap tunability and device performance metrics in reported metal halide perovskite alloys of a wide

Syntheses and catalytic oxotransfer actiVIties of oxo molybdenum(VI) complexes of a new aminoalcohol phenolate ligand

The new aminoalcohol phenol 2,4-di-tert-butyl-6-(((2-hydroxy-2-phenylethyl)amino)methyl)phenol (H2L) was prepared by a facile solvent-free synthesis and used as a tridentate ligand for new cis-dioxomolybdenum(vi)(L) complexes. In the presence of a coordinating solvent (DMSO, MeOH, pyridine), the complexes crystallise as monomeric solvent adducts while in the absence of such molecules, a trimer wit

The Smirnov class for spaces with the complete Pick property

We show that every function in a reproducing kernel Hilbert space with a normalized complete Pick kernel is the quotient of a multiplier and a cyclic multiplier. This extends a theorem of Alpay, Bolotnikov and Kaptanoğlu. We explore various consequences of this result regarding zero sets, spaces on compact sets and Gleason parts. In particular, using a construction of Salas, we exhibit a rotationa

Training predictive L2 processing with a digital game : prototype promotes acquisition of anticipatory use of tone-suffix associations

The present article introduces the concept of an educational game application aimed at providing training in predictive second language (L2) processing. The prototype of the game, focusing on Swedish tone-suffix associations, was tested during a two-week-period, with L2 learners whose native language lacked the targeted anticipatory linguistic cue. Results indicated that the game successfully prom

Investigation of heat transfer and fluid flow over pocket cavity in the rear part of gas turbine

The pocket cavity is generated at the transition part between the low pressure turbine (LPT) and outlet guide vane (OGV) in a gas turbine engine. Because the important connection with OGV, the heat transfer and fluid flow need to be investigated and analyzed. In the present work, a simplified triangular pocket cavity is built and heat transfer and fluid flow are investigated experimentally and num

Drell-Yan process in pA collisions : Path-integral treatment of coherence effects

In this work, we investigate production of Drell-Yan (DY) pairs in proton-nucleus collisions in kinematic regions where the corresponding coherence length does not exceed the nuclear radius, RA, and the quantum coherence effects should be treated with special care. The results for the nucleus-to-nucleon production ratio available in the literature so far are usually based on the assumption of a ve

Thermal stress analysis of a planar anode-supported solid oxide fuel cell : Effects of anode porosity

A Fuel cell is a highly efficient device for converting chemical energy in fuels to electrical energy and the electrical efficiency is strongly affected by the porosity in electrodes due to its close couplings with mass transfer and active sites for the electrochemical reactions, which will also cause changes in distribution of thermal stresses inside the electrodes. A three-dimensional computatio

Measurements of double-helicity asymmetries in inclusive J /ψ production in longitudinally polarized p+p collisions at s =510 GeV

We report the double-helicity asymmetry, ALLJ/ψ, in inclusive J/ψ production at forward rapidity as a function of transverse momentum pT and rapidity |y|. The data analyzed were taken during s=510 GeV longitudinally polarized p+p collisions at the Relativistic Heavy Ion Collider in the 2013 run using the PHENIX detector. At this collision energy, J/ψ particles are predominantly produced through gl

Measurement of the W±Z boson pair-production cross section in pp collisions at √s=13 TeV with the ATLAS detector

The production of W±Z events in proton–proton collisions at a centre-of-mass energy of 13 TeV is measured with the ATLAS detector at the LHC. The collected data correspond to an integrated luminosity of 3.2 fb−1. The W±Z candidates are reconstructed using leptonic decays of the gauge bosons into electrons or muons. The measured inclusive cross section in the detector fiducial region for leptonic d

Measurement of the top quark mass in the tt̄ → Dilepton channel from √s=8 TeV ATLAS data

The top quark mass is measured in the tt̄ → dileptonchannel (lepton=e, µ) using ATLAS data recorded in the year 2012 at the LHC. The data were taken at a proton-proton centre-of-mass energy of √s=8 TeV and correspond to an integrated luminosity of about 20.2fb-1. Exploiting the template method, and using the distribution of invariant masses of lepton-b-jetpairs, the top quark mass is measured to b

Measurement of the ttproduction cross-section using eμ events with b-tagged jets in ppcollisions at √s=13 TeV with the ATLAS detector

This paper describes a measurement of the inclusive top quark pair production cross-section (σtt̄) with a data sample of 3.2 fb−1of proton-proton collisions at a centre-of-mass energy of √s=13 TeV, collected in 2015 by the ATLAS detector at the LHC. This measurement uses events with an opposite-charge electron-muon pair in the final state. Jets containing b-quarks are tagged using an algorithm bas