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Improving pandemic preparedness and management : Lessons learned and ways forward : independent expert report

Epidemics and pandemics have shaped human history and will continue to do so. The COVID-19 crisis has shown that there is need to understand how Europe can ensure better management of and preparedness for them. This joint advice builds on lessons learned from the current and from previous pandemics. It analyses their complexity, drawing on insights from research and scholarship and taking European

A high temperature turbine blade heat transfer multilevel design platform

In this work, a fast and efficiently design method has been introduced. This design process consists of the overall design and the detailed design. For the overall design, one-dimensional pipe-network computations are employed to obtain several design cases quickly at the beginning. Meanwhile the solid domain geometry and mesh with cooling structures, i.e., film holes, impingement holes, and ribs

The Swedish National Airway Register (SNAR) : development, design and utility to date

Background: The Swedish National Airway Register (SNAR) was initiated in 2013 to ensure and improve the quality of care for patients with asthma and COPD. Aim: To describe the development and design of SNAR, and to study the 2019 data to evaluate its potential utility related to improvement of quality of care. Methods: SNAR includes data from patients with asthma (both children and adults) and COP

The relevance of silks to amyloids

At the heart of protein's aggregation are specific molecular events; and how they are modulated by changes in solvent conditions and temperature is key to our understanding and control of aggregation. A certain class of structural fibrous proteins may provide the answer. Indeed, spider silk and silkworm silk proteins have evolved to readily form ‘insoluble’ ordered structures. But, to date little

Transient gain of function of cannabinoid CB1 receptors in the control of frontocortical glucose consumption in a rat model of Type-1 diabetes

Here we aimed to unify some previous controversial reports on changes in both cannabinoid CB1 receptor (CB1R) expression and glucose metabolism in the forebrain of rodent models of diabetes. We determined how glucose metabolism and its modulation by CB1R ligands evolve in the frontal cortex of young adult male Wistar rats, in the first 8 weeks of streptozotocin-induced type-1 diabetes (T1D). We re

Tl concentration and its variation in a CsI(Tl) crystal for the CALIFA detector

One of the factors that can contribute to the resolution of long, doped inorganic scintillators used for nuclear spectroscopy is the variation of the dopant concentration over the length the detector crystal. In this work an investigation of such potential variations in one of the CsI(Tl) scintillators used in the calorimeter, CALIFA, of the R3B experiment at FAIR, has been performed using particl

Topology optimization of non-linear, dissipative structures and materials

Topology optimization is a mathematical tool for finding optimal distributions of material phases within a design domain. It is commonly used in early design stages to generate conceptual structural layouts. Ultimately, designs generated by topology optimization consist of distinct material phases with enhanced performance. Most research on topology optimization methods focuses on linear elastic m

Collaborative Fashion Consumption in Sweden and Spain : Market, environmental and behavioural insights

Within the context of a sharing economy, the BE-USE project aims to develop behavioural economics experiments that test, examine and generate policy recommendations to advance sustainable urban initiatives. It aims to increase the understanding of cognitive, motivational and contextual factors affecting decision-making processes and choices in urban sharing initiatives.This report is developed und

Gestational age-related reference values for Apgar score and umbilical cord arterial and venous pH in preterm and term newborns

INTRODUCTION: Despite much literature on reference values of acid-base status in umbilical cord blood at birth, there are as yet no studies performed to determine gestational age-dependent references in cord venous blood and no studies on preterm acid-base standards. Similarly, the normal reference range of Apgar scores for term and preterm infants has not yet been determined.MATERIAL AND METHODS: