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Treatment ideologies and working models replace each other quickly in today's society. During the 1980s a dramatic dismantling of the psychiatric institutions occurred. The health care system was supposed to be transferred to non-institutional care. This was, however, not possible for all groups of patients. At an institution, specialized in so called demanding patients and patients who received c
Modern power system is a complex dynamical system and one of the largest man-made systems. With recent driving forces like environmental concerns over air emissions, the modern power system is evolving towards an even more complex system. So it is necessary to handle the current challenges in power systems with simple approaches and avoid adding further complexity as much as possible. Also the imp
Helicobacter pylori may cause gastritis, gastric/duodenal ulcer and gastric cancer. During infection, most H. pylori are found in the gastric mucus layer, but some are attached to, or have penetrated, epithelial cells. The aim of this study is to characterize the binding of H. pylori to gastric mucins and to investigate host changes that occur after inoculation. Results: H. pylori binds to mucins
Hormone-sensitive lipase (HSL) and protein kinase B (PKB) are enzymes that in different ways are associated with lipid metabolism. While HSL is the well-known lipolytic enzyme responsible for hydrolysis of stored triacylglycerols in adipose tissue, PKB is a recently identified serine/threonine protein kinase, ubiquitously expressed and involved in signal transduction pathways induced by insulin an
Bone and soft tissue tumors (BSTT) constitute a heterogeneous group of neoplasms of mesenchymal and neuroectodermal origin. Although many BSTT are rare, it has become clear that BSTT are characterized by recurrent acquired chromosomal aberrations, and the general aim of this thesis have been to apply molecular genetic and molecular cytogenetic techniques to further characterize recurrent breakpoin
The thesis provides a discussion of the ecclesiology of the French Roman-Catholic theologian Henri de Lubac SJ (1896-1991) by showing how this is determined by his method of fundamental theology. I establish the term ?fundamental ecclesiology? for this inter-dependance of form and content, subject and object in theology; this is why his ecclesiology is sacramental in structure. I primarily use tex
Flexibility as well as constraints to the evolution of migration routes has the possibility of affecting large-scale patterns of geographical ranges of animals both by facilitating, but sometimes restricting, accessibility to and colonization of new regions. This dissertation concerns the broad-scale effects migration has on the distributional patterns of birds in the Arctic. I studied the circum
Malignant glioma is, with rare exceptions in younger adults, an uncurable brain tumor, as very few survive more than 1-2 years after diagnosis. Despite advances in recent years, current treatments such as surgery, radiotherapy and chemotherapy only prolongs the life of the patients. Because of the poor prognosis, several additional therapies have been investigated and are under development, such a
I share my fascination of bird flight with many others, and here I summarise my thesis on the subject. This thesis emphasises the mechanics of bird flight by focusing on flight mechanics, wake dynamics and flight performance. Gliding flight performance of a jackdaw was measured in a wind tunnel and I conclude that the current model for predicting optimum wingspan as a function of forward gliding
In this licentiate thesis the implications of a deliberate use of logistics knowledge have been investigated by describing and analyzing the use of a supply chain management approach in the construction industry.
A five-step approach is used in the thesis. First, theoretical models are developed from the supply chain management literature. Two models are elaborated; One model identifying sup
Results from experimental studies, as well as clinical studies, are used to elucidate the effects of ambient pressure changes on cochlear hydrodynamics and function. The perilymph pressure changes and the pressure release effects of the cochlear aqueduct (CA) and Eustachian tube (ET) in cats exposed to hypobaric pressure are elucidated. The focus is on the emergence of the pressure gradients betwe
Interleukin (IL)-1beta is one of the most pleiotropic and potent cytokines, produced predominantly by activated monocytes and macrophages. IL-1 plays an important role in normal immunoregulatory processes but also in pathophysiological inflammatory responses. In the present study, we developed a model for active IL-1beta secretion. A retroviral vector containing a cDNA construct encoding the matur
Sandy, calcareous grasslands are species rich temperate semi-natural grasslands. The species composition in 136 plots was analysed in relation to soil chemistry parameters; extractable P and N, soil pH and lime content. We found that that acidification and decalcification decrease species diversity and the number of red-listed species in these sandy grasslands. The microbial community was investig
Ischemic and traumatic brain damage are major causes of disability and death. While much effort has been spent to develop pharmacological treatments for these conditions, no neuroprotective drugs are in clinical use. Neuronal death following ischemia and trauma occurs in selected cell populations of the brain at various time points after the insult. It is believed that death of neurons are in part
In what ways can various perspectives, aims, circumstances, and directives influence music students and music teachers in different educational contexts such as primary school, Schools of music and performing arts (SMPA), folk high school, and upper secondary school, viewed from a Nordic perspective?A common characteristic for all these types of schools is that they can be part of an educational a
Haemophilia A (HA) is caused by defective synthesis of coagulation factor VIII(FVIII), which has serious effects on haemostasis; joints being the most common site of bleeding. The development of FVIII replacements has improved the situation for patients with haemophilia such that chronic arthropathy can be prevented, and life expectancy and the quality of life have increased. However, approximatel
During the past 15 years lung transplantation has been established as a therapeutic option for patients with end-stage pulmonary disease. The results have improved over time and some transplantation centers now show 1-year survival rates above 80%. The number of donors has remained relatively constant during later years but the demand is increasing resulting in longer waiting times and an increasi
AIM: To study infantile colic in terms of occurrence, risk factors in pregnancy, distress patterns, caregiving practices, and outcome. STUDY DESIGNS: Paper I: Population study, 376 mothers and newborn infants, diaries or telephone interviews. Paper II: 116 colic and 119 control cases, telephone interviews, and diaries. Papers III-IV: Population study, 1099 mother-infant dyads, pregnancy inquiries
The subject of this thesis is the clinical use of transesophageal echocardiography (TEE) in patients with stroke or atrial fibrillation. Subjects were examined with echocardiography and sonography of the carotid artery. A control group of randomly selected volunteers without cerebrovascular disease was compared to patients with ischemic stroke. Cardiac pathology was classified as minor potential e
All elbow fractures between 1969 – 1979 (n=2965) registered at the radiographic archives at the Malmö University Hospital, where all radiographs are saved since a century, were evaluated. Fractures of the radial head and neck were classified according to the by Broberg and Morrey modified Mason classification. A Mason type I fracture is a less than 2 mm displaced fracture of the radial head or nec
