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Motivational Strategies and the Reframing of English : Activity Design and Challenges for Teachers in Contexts of Extensive Extramural Encounters

Motivational strategies are underresearched, and studies so far conducted have been in sociolinguistic contexts where English is not extensively encountered outside the classroom. Given also that little is known about strategies relating to the design and content of classroom activities, the purpose of this study is to identify and critically evaluate strategies focusing on activity design and con

Engagement with Technology : Gaming, Immersion and Sub-Optimal Experiences

This conceptual article focuses on student engagement, and the use of digital games in language classrooms. In making a contribution to the mapping of student engagement across SLA (Dörnyei, 2019a), and in line with the need to use established theories to develop insights into engagement when L2 learning involves digital games, a case is made for the concept of immersion (Brown & Cairns, 2004)

Individual differences of bacterial degradation of starch in the upper gastrointestinal tract evaluated in a modified in vitro model

Avoiding absorption in the upper gastrointestinal tract is one of the challengesconsidering targeted colon delivery but not much attention has been paid tomicrobial activity of vector material in saliva and small intestine. The aim of thepresent study was to develop an in vitro prototype model for evaluatingdigestion of encapsulation material by oral bacterial species based on readilyobtainable sa

Differential splice isoforms of mouse CDK2 play functionally redundant roles during mitotic and meiotic division

In most mammals, the cell cycle kinase; cyclin-dependent kinase 2 (CDK2) is expressed as two major isoforms due to alternative splicing. The shorter CDK2 isoform: CDK2S, is expressed constitutively during the cell cycle and can be detected in several tissues. In contrast, the longer isoform: CDK2L, shows preferential expression in meiotically dividing cells and upon S-phase entry in the mitotic cy

ANN-modell för att bestämma renoveringsbehov av vattenledningar -- Utvärdering av viktiga attribut med tillämpning för Umeå kommun

Sveriges vattenledningsnät kräver kontinuerliga och stora in- vesteringar och måste underhållas på ett effektivt sätt; syftet med den här studien var därför att utröna vilka ledningsattribut som är viktigast för att i en ANN-modell identifiera ledningar med hög risk för läckage. Detta gjordes genom att först använda attri- buturvalsmetoderna ReliefF och Recursive Feature Elimination (RFE) tillsamman

Repurposing statins and phenothiazines to treat chemoresistant neuroblastoma

Relapse and treatment resistance are common in children with high-risk neuroblastoma, and novel therapies are needed. Conventional drug discovery is slow, expensive, often fails in practice, and consequently falls short in addressing pediatric and rare conditions. In such instances, drug repurposing is a promising strategy. Here, we used two independent in silico prediction tools including machine

Are evaluative bibliometrics neoliberal? A historical and theoretical problematization.

In this article, we problematize the notion that the continuously growing use of bibliometric evaluation can be effectively explained by ‘neoliberal’ ideology. A prerequisite for our analysis is an understanding of neoliberalism as both denoting a more limited set of concrete principles for the organization of society (the narrow interpretation) or as a hegemonic ideology (the broad interpretation

Cross-Ancestry DNA Methylation Marks of Insulin Resistance in Pregnancy : An Integrative Epigenome Wide Association Study

Although there are some epigenome-wide association studies (EWAS) of insulin resistance, most of them did not replicate their findings and are focused in populations of European ancestry limiting the generalizability. In EPIPREG (294 Europeans and 162 South Asians), we conducted an EWAS of insulin resistance in maternal peripheral blood leukocytes, with replication in Born in Bradford (n=879; 430

The use of carvone in consecutive patch testing

Background: Carvone (l-carvone) is a mint-tasting flavour additive that most of us is exposed to and can cause allergic contact reactions. Objectives: To analyse the frequency and the relevance of positive carvone reactions in a dermatitis population. Method: A retrospective analysis of dermatitis patients consecutively tested with carvone from 2017 to 2021. Data were retrieved from the department

A phenome-wide comparative analysis of genetic discordance between obesity and type 2 diabetes

Obesity and type 2 diabetes are causally related, yet there is considerable heterogeneity in the consequences of both conditions and the mechanisms of action are poorly defined. Here we show a genetic-driven approach defining two obesity profiles that convey highly concordant and discordant diabetogenic effects. We annotate and then compare association signals for these profiles across clinical an

Financial incentives for vaccination do not have negative unintended consequences

Financial incentives to encourage healthy and prosocial behaviours often trigger initial behavioural change, but a large academic literature warns against using them. Critics warn that financial incentives can crowd out prosocial motivations and reduce perceived safety and trust, thereby reducing healthy behaviours when no payments are offered and eroding morals more generally. Here we report find

Uppsalaskolan och rättighetsbegreppet

I denna uppsats undersöks uppsalaskolans syn på rättighetsbegreppet med utgångspunkt i texter av Axel Hägerström, Vilhelm Lundstedt och Ingemar Hedenius. Syftet är att jämföra hur de tre författarna ser på rättighetsbegreppet. Uppsalaskolan har ofta framställts som en enhetlig rättsfilosofi, men i själva verket hade företrädarna skilda ståndpunkter i viktiga frågor. Alla tre författarna är i all vThis paper examines the Uppsala school of thought’s (Uppsalaskolans) approach to the concept of rights. The investigation is based on texts by the three legal philosophers Axel Hägerström, Vilhelm Lundstedt and Ingemar Hedenius. The Uppsala school of thought has often been presented as a coherent philosophy of law, but the representatives in fact held differing positions on a number of important i

Att vara barnet - En studie om barn till psykiskt sjuka föräldrar

The aim of this study was to examine children living with a mentally ill parent and see what help and support there is for these children and if it is enough. The study was based on nine posts on the website Kuling, which is a website for children with a mentally ill parent, and five qualitative, semi-structured interviews with professionals working with this issue. The interviews took place in a

"...jag tror ju inte ens att vi ser toppen av isberget." En kvalitativ studie om skolkuratorers perspektiv på kränkningar och mobbning på sociala medier.

The aim of the study was to explore how school counselors experience and describe youth´s vulnerability on social media. Furthermore, the study intended to explore the school's preventive and remedial work to combat abusive treatment or bullying on social media. The study had a qualitative approach including six semi-structured interviews that were conducted by school counselors working at mid

Extreme value modeling of wind effect on dune erosion on the Coast of ̈Angelholm

The movement of the coast line, due to erosion in one direction or aggregation in theother is a natural process as waves, wind as well as the geological nature of the coast itselfare affecting it. Sand dunes are the main protection coasts have at their disposal againstfloods during storm surges or from more passive but long range rainfalls. As many of the coastal areas have a dense population and