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Epigenetics of type 2 diabetes mellitus and weight change — a tool for precision medicine?

Pioneering studies performed over the past few decades demonstrate links between epigenetics and type 2 diabetes mellitus (T2DM), the metabolic disorder with the most rapidly increasing prevalence in the world. Importantly, these studies identified epigenetic modifications, including altered DNA methylation, in pancreatic islets, adipose tissue, skeletal muscle and the liver from individuals with

Probabilistic analysis of climate change impact on chloride-induced deterioration of reinforced concrete considering Nordic climate

The impact of climate change on the deterioration of reinforced concrete elements have been frequently highlighted as worthy of investigation. This article addresses this important issue by presenting a time-variant reliability analysis to assess the effect of climate change on four limit states; the probabilities of corrosion initiation, crack initiation, severe cracking, and failure of a simply

“Black race”, “Schwarze Hautfarbe”, “Origine africaine”, or “Etnia nera”? The absent presence of race in European pharmaceutical regulation

Current scholarship on race in Europe has described race as an “absent presence”. However, little is known about the dynamics of the absentness and presentness of race, including how various social processes operating at distinct levels (e.g., supranational and national) influence the uses of race and ethnicity concepts. We begin addressing this gap by examining racialised pharmaceutical regulatio

The influence of business model on the development of 3D food printing technology for dysphagia patients in elderly care

Dysphagia, or difficulty swallowing, affects 10–30 % of persons above 65 years old. Texture-modified, easy-to-swallow, puree-like food in the form of timbales is usually served to this group of patients. Due to the characteristics of timbale, its appearance only remotely reminds of the original ingredients, leading to reduced appetite, reduced nutrition intake, and even malnutrition. 3D food print

Autoantibodies against red blood cell antigens are common in a Malaria endemic area

Plasmodium falciparum malaria can cause severe anemia. Even after treatment, hematocrit can decrease. The role of autoantibodies against erythrocytes is not clearly elucidated and how common they are, or what they are directed against, is still largely unknown. We have investigated antibodies against erythrocytes in healthy adult men living in a highly malaria endemic area in Uganda. We found anti

New Insights in the Control of Fat Homeostasis : The Role of Neurotensin

Neurotensin (NT) is a small peptide with pleiotropic functions, exerting its primary actions by controlling food intake and energy balance. The first evidence of an involvement of NT in metabolism came from studies on the central nervous system and brain circuits, where NT acts as a neurotransmitter, producing different effects in relation to the specific region involved. Moreover, newer interesti

AUGMENTATION OF LABOUR AND FETAL OUTCOMES IN RELATION TO BIRTH POSITIONS: A SECONDARY ANALYSIS OF AN RCT EVALUATING BIRTH SEAT BIRTHS

Background: The WHO advises against recumbent position for longer periods during labour and birth. It has been suggested that upright posi-tions may improve childbirth outcomes and reduce the need for oxytocin augmentation. However RCTs of interventions to encourage upright positions are scarce. The aims of this study were to assess whether there is a relationship between the use of oxytocin augme

Experimental determination of k Qfactors for two types of ionization chambers in scanned proton beams

Objective. Experimental determination of beam quality k Q factors for two types of Farmer ionization chambers, NE2571 and IBA FC65-G, in a scanned proton beam for three nominal energies (140 MeV, 180 MeV and 220 MeV) based on water calorimetry. Approach. Beam quality correction factors were determined comparing the results obtained with water calorimetry and ionometry. Water calorimetry was perfor

M&A-transaktioner på fastighetsmarknaden - Varför sker de och vilka effekter ger de?

Under 2021 genomfördes ett stort antal M&A-transaktioner på fastighetsmarknaden i Sverige jämfört med tidigare år. Syftet med studien är att studera motiv till M&A-transaktioner på fastighetsmarknaden, hur dessa skapar värde för fastighetsbolagen samt vilka effekter de ger på marknaden. Studien genomfördes genom att läsa litteratur och tidigare forskning på ämnet samt studera M&A-tra

Female Migrants in Search of Jobs: The Role of Social Capital in Labor Market Integration

The labor market integration of immigrants in general, and female migrants in particular, remains a central developmental objective for counteracting inequalities within societies across Europe. Previous studies put forth the concept of social capital, the resources linked to an individual's network of social connections, to explain immigrants’ diverging labor market trajectories. Policy-maker

M&A legal due diligence process-A qualitative study of law firms perspective

Att göra företagstransaktioner “work” är en av de svåraste uppgifterna i näringslivet. Due diligence vilket brukar kallas ”företagsbesiktning” på svenska är ett sätt att samla in och granska information och risker om ett företag. Det finns olika former av due diligence, varav de sedvanliga formerna är kommersiell, financial och legal due diligence. Både köpare eller säljare anlitar ofta en advokat

Medborgardeltagande och dialog i den kommunala planeringen - en fallstudie av området Lanna-Hidinge i Lekebergs kommun

The ideals of civic participation are within much of current planning theory regarded as ways of ensuring the democratic and equitable values of planning processes, as well as offering local knowledge to those in power and awarding citizens the influence of being a part of shaping the spaces around them. However, they have also been the subject of much scrutiny; critical assessments of such activi

Kriteriet hederligt levnadssätt i 11 § femte punkten MedbL i ett rättshistoriskt perspektiv

Medborgarskap är en viktig status för individen. Medborgarskap innebär både rättigheter och skyldigheter för staten och för individen. Att byta och förvärva ett nytt medborgarskap är en stor ockasion i en persons liv. Denna uppsats kommer att granska kriteriet hederligt levnadssätt som återfinns i 11 § femte punkten MedbL. Intressant nog har detta kriterium utvecklats främst genom praxis. Denna u

Sociala kretsars påverkan på matsvinnsbeteende

How we manage resources, in this case food, based on our culture is the core interest of human ecology. According to systems analysist Donella Meadows, cultural factors, i.e. our mindset, are the most difficult intervention points to access for system change - but also the most effective. This essay examines through a survey and a smaller experiment how prescribed norms and attitudes of social cir

Komplexa arbetsrelationer - kvalificering av arbetstagare gällande plattformsarbete

Det ämne uppsatsen behandlar gäller arbetstagarbegreppet och plattformsarbete ur ett komparativt nationellt, svenskt arbetsrättsligt, och EU-arbetsrättsligt perspektiv. Digitaliseringen av arbete har lett till delningsekonomins framväxt, såväl har nya mer flexibla och diversifierade anställningsformer utvecklats. Anställningsformen plattformsarbete innehar en stor heterogen arbetskraft med många oThe notion of the employee and work through platforms is to be the subject of the essay, examined from a comparative view of both national and EU-labour legislation. The digitalisation of work has brought forth the sharing economy, thence more flexible and diversified forms of employment. One of which, is platform work with a heterogeneous workforce causing legal disparative concerns. It is a form