Endemic diseases are caused by environmental and genetic factors. While in this special issue several chapters deal with environmental factors, including infections, the present focus is on genetic causes of disease clustering due to inbreeding and recessive disease mechanisms. Consanguinity is implying sharing of genetic heritage because of marriage between close relatives originating from a comm

Experiences of relocation in dementia care from the perspective of six care workers. International Journal of Older People Nursing6, 93-101 doi: 10.1111/j.1748-3743.2010.00246.x Background. Relocation of persons with dementia might be considered when quality of care cannot be sustained due to increasing needs. Relocation has been studied from the aspects of mortality and morbidity. Aim. To explore

OBJECTIVE: Neutrophil infiltration is a key regulator in the pathophysiology of acute pancreatitis (AP), although the impact of Toll-like receptors (TLRs) in AP remains elusive. The aim of this study was to define the role of TLR2 and TLR4 in leukocyte recruitment and tissue damage in severe AP. EXPERIMENTAL DESIGN: AP was induced by retrograde infusion of sodium taurocholate into the pancreatic d

Indoor air measurements were conducted in one unoccupied apartment of a ‘near-zero-energy’ residential building with a unique, wooden construction. Ozone, NO2, fine particles and volatile organic compounds, formaldehyde, acetaldehyde and peroxyacetyl nitrate (PAN) were measured under ‘as is’ conditions and after intentional intervention by adding ozone to simulate an ambient air ozone episode. Und

OBJECTIVE:: To describe the characteristics of patients undergoing multiple groin hernia repairs and to identify strategies that prevent further recurrence. SUMMARY BACKGROUND DATA:: Although relatively infrequent, recurrent groin hernias where several repairs have previously been undertaken constitutes a major problem in hernia surgery. Low numbers and heterogeneity have made it difficult to perf

Quality is an aspect of high importance in software development projects. The software organizations have to ensure that the quality of their developed products is what the customers expect. Thus, the organizations have to verify that the product is functioning as expected and validate that the product is what the customers expect. Empirical studies have shown that in many software development pro

The impact of European Union law on the regional and local levels in the Member States has been underestimated for a long time now. Today, however, it is clear that the impact of European Union law on these levels is important, not least as a consequence of the deregulation that has been carried out in most Member States in recent years. As local markets open up for competition, the scope of EU la

Critical infrastructures provide society with services that are essential for its functioning and extensive disruptions of these give rise to large societal consequences. Vulnerability analysis gives important decision information concerning improving their ability to withstand strains. To analyze vulnerabilities in infrastructures models for estimating consequences due to failures are needed. Con

Load demand in residential houses is a significant contributor to peak load problems experienced by utilities. The knowledge about demand variation in households is fairly limited as well as the use of various tools to analyze the demand. Many utilities have recently installed interval (hourly) metering at their residential customers. The availability of hourly data is a significant progress, howe