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Treatment strategy, disease activity, and outcome in four cohorts of patients with early rheumatoid arthritis

Objective-To compare four different inception cohorts of patients with early rheumatoid arthritis (RA) with respect to treatment strategies, disease activity, and outcome during a five year follow up period. Method-Data from cohorts of patients with early RA, with a standardised assessment at least every six months for five years from four different centres, were included in one database. Owing to

A method for population studies of butterflies at the landscape scale.

I here propose a modification of the English butterfly census method (Pollard 1977) for studies of large areas with a relatively low density of butterflies. The transect line should not be more than 10 m from any point in open terrain and open forests, but only 5 m from sunny edges and patches with a high density of flowers. The transect line is adjusted between visits to most intensively cover si

Acute confusion in orthopaedic care. With the emphasis on the patients' view and the episode of confusion.

The aims of this thesis were to investigate factors of significance for the development of acute confusional state (ACS), the confusional episodes, the lived experiences of having been confused in elderly patients admitted for emergency or elective surgery in orthopaedic care. A further aim was to investigate the nurses’ view of the ACS and the encounter with patients who developed ACS. A case stu

Simulating the palaeorecord of northern European lakes using a coupled lake-catchment model

A coupled lake-catchment model was developed to examine the controls on lake-level changes in currently overflowing lakes during Holocene. The lake energy-balance is simulated as the one-dimensional vertical heat transfer by eddy diffusion and convective mixing. The accumulation and ablation of lake ice, and snow cover on the ice, is simulated thermodynamically. The lake water-balance is given by

Measurements of stellar magnetic fields using synthetic spectrum fitting

A sample of Ap and Bp stars have been investigated with respect to theirsurface magnetic field using synthetic spectrum fitting. The advantageof this technique is the simplicity in determining the surface fieldstrength and the possibility to apply it to objects whose spectrum doesnot display resolved Zeeman components. We show the usefulness of themethod by demonstrations on stellar spectra with r

Strategies for feeling secure influence parents' participation in care

This study investigates what makes parents of hospitalized children feel secure and factors influencing their level of participation. It also studies, whether the degree to which parents participate affects their child's pain and sleep during hospitalization. Questionnaires were distributed to a series of parents whose children were discharged from two paediatric surgical wards and one paediatric

A homozygous nonsense mutation (428G -> A) in the human secretor (FUT2) gene provides resistance to symptomatic norovirus (GGII) infections

Noroviruses (formerly Norwalk-like viruses) are a major cause of acute gastroenteritis worldwide and are associated with a significant number of nosocomial and food-borne outbreaks. In this study we show that the human secretor FUT2 gene, which codes for an alpha(1,2)-fucosyltransferase synthesizing the H-type 1 antigen in saliva and mucosa, is associated with susceptibility to norovirus infection

Prophylaxis and treatment of bleeding complications in von Willebrand disease type 3.

Treatment of type 3 von Willebrand disease (vWD) relies on infusion with plasma-derived factor concentrates containing von Willebrand factor (vWF). Patients with types 1 and 2 vWD who do not respond satisfactorily after receiving desmopressin need treatment with concentrates. The rationale for long-term prophylaxis in vWD is obvious: prophylaxis has been successfully used in hemophilia, and joint

Measurements of ATP in forest humus

The measurement of ATP as an estimate of microbial biomass C in humus was studied. Three different acid extractants, H2SO4, TCA and H3PO4 were compared, as well as two different buffers, Tris and arsenate. No difference in extraction efficiency was found when the light output was converted to ATP content using internal ATP standards, but the different extraction agents and buffers influenced the l

The gut microbiota and diabetes : research, translation, and clinical applications – 2023 Diabetes, Diabetes Care, and Diabetologia Expert Forum

This article summarises the state of the science on the role of the gut microbiota (GM) in diabetes from a recent international expert forum organised by Diabetes, Diabetes Care, and Diabetologia, which was held at the European Association for the Study of Diabetes 2023 Annual Meeting in Hamburg, Germany. Forum participants included clinicians and basic scientists who are leading investigators in

Promoting public sector innovation: who does what, when and how?

A strong and prevailing innovation imperative is sweeping across the public sector and despite a growing literature on public sector innovation (PSI), the actors driving these processes tend to end up in the background of analysis. Based in an analytical framework of narrative theory and organization studies, and the efforts to introduce Social Impact Bonds (SIB) in Sweden as empirical case, the a