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It has previously been shown that infant mortality clusters in a subset of families, a phenomenon which was observed in historical populations as well as contemporary developing countries. A transmission of death clustering across generations has also been shown in Belgium, but it is unknown whether such effects are specific to the studied context or are also found in other areas. The current arti

Expression of fat mass and obesity-associated gene (FTO) and ADP-ribosylation factor-like 15 (ARL15) in human islets is inversely correlated with HbA1c. However, their impact on insulin secretion is still ambiguous. Here in, we investigated the role of FTO and ARL15 using GRINCH (Glucose-Responsive Insulin-secreting C-peptide-modified Human proinsulin) clonal rat β-cells. GRINCH cells have inserte

The role of terrestrial organic carbon for recipient aquatic ecosystems is intensively researched. A multitude of studies now show that terrestrially-derived carbon supports a significant share (allochthony) of consumer biomass in many freshwaters. However, little is known about the mechanisms by which terrestrially-derived carbon is transferred to the level of metazoan zooplankton, and whether th

An important component of the carbon cycle is the lateral flow of dissolved organic carbon (DOC) from terrestrial ecosystems to streams and rivers. The fate of this carbon depends very much on the bioavailability of DOC (BDOC), which may determine whether DOC is returned to the atmosphere as CO2 or deposited in sediments. This study focuses on the linkages between stream DOC composition, optical c

Return to Kashgar – the Jarring Collection of Uyghur Manuscripts Kashgar was a major crossroads for trade and culture along the Eurasian Silk Route for thousands of years, a place where Turkic, Persian, Arab, Chinese and other groups interacted. The Lund University Library is privileged to hold some 600 handwritten books from the sixteenth to the twentieth centuries from cities in this region like

Venomous animals have evolved diverse molecular mechanisms to incapacitate prey and defend against predators. Most venom components disrupt nervous, locomotor, and cardiovascular systems or cause tissue damage. The discovery that certain fish-hunting cone snails use weaponized insulins to induce hypoglycemic shock in prey highlights a unique example of toxins targeting glucose homeostasis. Here, w

Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by hyperglycemia resulting from defects in insulin secretion and/or insulin action. Increasing evidence suggests that inflammation played an important role in the pathogenesis of T2DM. Prospective studies on the link between immunoglobulins concentrations and the risk of T2DM in adults are limited. We developed a cohort study in

This data package contains high accuracy CO2 dry air mole fractions from 58 ICOS and non-ICOS European observatories at in total 132 observation levels, collected by the ICOS Atmosphere Thematic Centre (ATC) and provided by the station contributors. The package is part of the Globalviewplus v8.0 data product, released in 2022 and is intended for use in carbon cycle inverse modeling, model evaluati

Risk assessment of pesticide impacts on remote ecosystems makes use of model-estimated degradation in air. Recent studies suggest these degradation rates to be overestimated, questioning current pesticide regulation. Here, we investigated the concentrations of 76 pesticides in Europe at 29 rural, coastal, mountain, and polar sites during the agricultural application season. Overall, 58 pesticides