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Lipid-associated macrophages transition to an inflammatory state in human atherosclerosis, increasing the risk of cerebrovascular complications

The immune system is integral to cardiovascular health and disease. Targeting inflammation ameliorates adverse cardiovascular outcomes. Atherosclerosis, a major underlying cause of cardiovascular disease, is conceptualized as lipid-driven inflammation in which macrophages play a nonredundant role. However, evidence emerging so far from single-cell atlases suggests a dichotomy between lipid-associa

Mat och levnadskonst : Arkiater Linné ger råd

The art of living and the art of eating: Professor Linnaeus recommends. By Gunnar Broberg. As professor of medicine, Linnaeus taught dietetics. He followed the pattern outlined by Galen and Regimen salernitatis, adding an extensive material originating from general cultural history and his own experience.Early in his life he wrote Diaeta naturalis, a collection of rules focusing the blessings of n

The conundrum of asymptomatic carotid stenosis-determinants of decision and evidence

Management of asymptomatic carotid disease continues to challenge medical practice and present evidence is often conflicting. Stroke is a significant burden in Public Health and 11% to 15% appear as first neurologic event associated with asymptomatic carotid stenosis. Randomized trials provided support for Guidelines and Recommendations to intervene on asymptomatic stenosis, but at a known cost of

Så kan formel för vuxna skatta glomerulär filtration hos barn

Omräkning av barns (≥2 år) kreatininvärden till motsvarande värden vid 18 års ålder och applicerade i Lund–Malmö-formeln för vuxna ledde till avsevärt förbättrad skattning av GFR bland barn vid uppmätt GFR <75, bibehållen noggrannhet ≥75 ml/min/1,73m2 och likvärdig med pediatriska formler.Lund–Malmö-formeln kan användas under hela livet ≥2 år utan plötsliga artificiella förändringar i skattad GFR

Cross-country differences in preferences for leisure

The starting point of this paper is to document considerable cross-country variation in the “labor wedge”, a common measure of labor market frictions. Its variation is theoretically isomorphic to differences in a preference-for-leisure parameter. The paper proceeds to investigate what might explain the variation. It presents three separate empirical exercises supportive of the view that, to a subs

Enabling social participation for older people : The content of reablement by age, gender, and level of functioning in occupational therapists’ interventions

Background: Social participation and the ability to build and maintain social relationships is emphasized as important for older people’s health and well-being. Aim: To explore if social participation is addressed and whether age, gender and level of functioning are associated with the composition of occupational therapy interventions within the context of reablement. Method: In this cross-section

The seaweed experience: exploring the potential and value of a marine resource

The article addresses the broader relationships between seaweed and algae as a marine resource, destination development, and sustainability. In many European countries, an industry around seaweed has emerged, ranging from high-end restaurants that provide their customers with local, seasonal and sustainableingredients, to entrepreneurs offering “harvest your own seaweed”-tours. In this explorative

Marketization in Crisis : The Political Economy of COVID-19 and the Unmaking of Public Transport in Stockholm

While measures to prevent the spread of COVID-19 disturbed both global and local markets, some commentators also argued that the pandemic could be seen as the beginning of the end of neoliberalism. Although neoliberal reforms have come under pressure, little is known about the implications of COVID-19 in or across specific sectors. Scaling down the rich theoretical–historical debates about neolibe

Towards health systems resilience to extreme weather events: Managing health needs during floods in Cambodia : EBA Dissertation Brief 2020:07

Extreme weather events like floods are expected to become more common asclimate change continues, putting health at risk. Systems should be able tocontinue delivering essential health services when shocked by events like floodsand provide care for the expected new health needs caused by the shock.Resilient health systems have the capacity to maintain their functions and tochange when shocked, enab

Docforia : A Multilayer Document Model

In this paper, we describe Docforia, a multilayer document model and application programming interface (API) to store formatting, lexical, syntactic, and semantic annotations on Wikipedia and other kinds of text and visualize them. While Wikipedia has become a major NLP resource, its scale and heterogeneity makes it relatively difficult to do experimentations on the whole corpus. These experimenta

Tech-savvy men and caring women: Middle school students’ gender stereotypes predict interest in tech-education

The labor market is strongly gender segregated with few women working in the tech sector (e.g. IT) and few men working in the care sector (e.g. nursing). We tested the hypothesis that middle school students strongly associate technology with men and caregiving with women, and that this relates to girls’ lower interest in tech-focused educations. We measured technology/caregiving gender stereotypes

Joint Handwritten Text Recognition and Word Classification for Tabular Information Extraction

In this paper, we present a system for extracting tabular information from loosely structured handwritten documents. The system consists of three parts, (i) a u-net like CNN-based method for text detection and segmentation, (ii) a new attention-based method for simultaneous text recognition and classification of word-parts, and (iii) a method for matching the word parts into a tabular structure fo

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

Although physical activity and sedentary behavior are moderately heritable, little is known about the mechanisms that influence these traits. Combining data for up to 703,901 individuals from 51 studies in a multi-ancestry meta-analysis of genome-wide association studies yields 99 loci that associate with self-reported moderate-to-vigorous intensity physical activity during leisure time (MVPA), le

Public perception of fire safety and risk of timber buildings

As a dominant representative of biobased construction materials, an increased use of timber bears potential to contribute to climate change mitigation. This work investigated public attitudes towards timber as a building material, particularly focussing on the perception of fire safety properties and associated risks. In past studies timber’s susceptibility to fire was often acknowledged by stakeh