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Water and Protein Dynamics in Biological Systems Studied by Magnetic Relaxation Dispersion

The results presented in this thesis demonstrate that the magnetic relaxation dispersion (MRD) technique can provide information of relevance to protein biophysics, magnetic resonance imaging and cell biology. By immobilizing proteins with covalent cross-links, intermittent protein dynamics on the previously inaccessible ns-µs time scale could be probed with MRD via the exchange of water molecule

Institutions and the Geography of Innovation: A Regional Perspective

Economic geographers have long been intrigued by the role of institutions in innovation processes. It has been argued that differences in institutions are among the factors explaining the uneven innovative capacity across and within countries. The regional innovation system approach highlights the interrelationships of firms, universities, governmental authorities and other organizations, as well

Non-formal Learning through Ludic Engagement within Interactive Environments

daptive responsive environments that encourage interaction for children with severe disabilities offer a distinct potential for play and learning in rehabilitation. Physical training and therapy for these children is often enduring, tedious, and boring through repetition - and this is often the case for both the child and the facilitator/therapist. Despite this, little is yet known about how the u

Polyurethane - occupational exposure, biomarkers and symptoms

Isocyanates may cause occupational asthma, rhinitis, and hypersensitivity pneumonitis. However, the mechanisms behind initiation of the disorders and the relations between exposure and effect are insufficiently elucidated. Means to biomonitor exposure and risk would be valuable. A case, exposed to heated polyurethane, displayed metabolites of 4,4'-dipheylmethane diisocyanate in blood and urine, an

Photon Dose Calculations in a Fluence-Based Treatment Planning System: Data Processing, Implementation and Validation

The accuracy of dose calculations for various aspects of a treatment planning system (TPS) using an energy fluence beam modelling has been evaluated. The investigated TPS uses a beam model, which separates the energy fluence into a number of sources in the treatment head. The energy fluence components are transported towards the patient and, together with the scatter generated in the patient, yiel

Reading John Climacus: Rhetorical Argumentation, Literary Convention and the Tradition of Monastic Formation

This thesis offers an investigation of the literary form and the literary composition of The Ladder by John Climacus, as well as a study of how the author uses the tradition to form his reader. Besides a brief introduction with a survey of the previous research, the study comprises four chapters. In the first chapter it is shown, from a number of detailed text analyses, that the material in the s

Hemicelluloses from Agricultural and Forestry Crops Isolation, Characterisation, and Enzymatic Hydrolysis

Hemicelluloses are tremendous sources of renewable raw materials, which utilisation have the potential to be highly increased in the future. Hemicelluloses are among the major groups of compounds in plant cell walls, together with cellulose and lignin. These three components are closely associated, making them difficult to separate from each other. Hemicelluloses are complex polysaccharides and tw

Mikrokosmos Förvaltare och Skapelsens Integritet, Den Teologiska Antropologin i Kyrkornas Världsråds JPIC-process med särskild hänsyn till skapelsens integritet

The aim of this dissertation is to discuss the two theologic anthropological concepts microcosm and steward within the World Council of Churches project called the JPIC-process - their JPIC stands for justice, peace and the integrity of creation - and to relate the two anthropological concepts to each other using a theological correlation method. After an introduction the JPIC-process, which offic

Simulation and execution of autonomous robot systems

Traditional off-line programming is not enough in order to use the full potential of virtual models and simulation system in industrial robot applications. The interface between off-line programming system and the robot controller is today restricted to program transfer. In this way a large amount of information is lost since typical robot programming languages is rather limited. If the virtual m

“No Friends but the Mountains” Understanding Population Mobility and Land Dynamics in Iraqi Kurdistan

The link between population mobility and environmental change is fundamental for our understanding of how future global environmental changes will affect our societies, and also how the increased mobility will change our role in the Earth system. Climate change has been predicted as a major cause of human migration, both voluntary and forced, through for example increased storm and drought frequen

Ambivalent Friendship : Anglican Conflict Handling and Education for Peace in Jerusalem 1920-1948

This thesis concerns a religious actor in the civil society in times of violent conflict. During the British Mandate period in Palestine, Jewish, Muslim and Christian children studied together at Anglican missionary schools. At this time Jerusalem bore all the imprints of ethnic and religious separation and division. The Anglican educational project became part of the efforts made by the Anglican

Visually guided swimming in box jellyfish: A study of swimming behaviour in response to visual stimuli

Most animals use eyes to guide their behaviour. Analysing, and understanding, visually guided behaviours gets more complicated the more advanced the animal gets. Box jellyfish provide a relatively simple system for understanding visually guided behaviours. They have a limited nervous system, but they also possess a visual system that is quite impressive for a jellyfish. Box jellyfish have 24 eyes

Chemical communication in mating shore crabs Carcinus maenas

Locating and evaluating a suitable partner for mating is one of the most important events in any sexually reproducing organism. To achieve this, an animal must be able to locate its partner over both long and short distances, and finally evoke the proper mating behaviour. This is made possible by use of conspecific signals picked up by one or several sensory systems, the most well investigated bei

On LFSR based Stream Ciphers - analysis and design

Stream ciphers are cryptographic primitives used to ensure privacy in digital communication. In this thesis we focus on stream ciphers built using Linear Feedback Shift Registers (LFSRs). Several different stream ciphers are analysed and new attacks are presented. In addition, two new stream ciphers are presented, both based on the same design. The first attack is performed on SOBER-t16 and SOBER

The Gulf Cooperation Council : Its Nature and Achievements

When Britain decided, in 1968, to terminate its official colonial presence in the Persian (Arabian) Gulf as of 1971, this action prompted the Gulf Arab States (Kuwait, Bahrain, Saudi Arabia, Qatar, United Arab Emirates, and Oman) to start the search for a form of partnership that would bring them together to better cope with the insecurity and danger surrounding them and their regimes. A key probl

Studies on mRNA turnover in bacteria

Genetic information, which is stored in DNA, is transferred to messenger RNA (mRNA) in a process called transcription. mRNAs are then translated by ribosomes into proteins which, with some important exceptions, catalyze chemical reactions in cells. Since cells must be able to adapt to changes in the environment, mRNAs must be unstable. The present investigation concerns mRNA degradation mainly in

Profiling the cancer proteome

Cancer is a complex and heterogeneous disease where cells have started to grow uncontrolled and this disease remains a major health problem. Because of diffuse symptoms it often presents at a late stage. Insufficient understanding of the different phenotypes hinders the development of targeted therapeutics and consequently patients show a diverse range of responses to a given treatment. This thes

ENDOTHELIAL- EPITHELIAL INTERACTIONS Blood vessels friends or foes?

Diabetes affects enormous amounts of patients. In type 1 diabetes the insulin producing β cells in the islet of Langerhans are destroyed by the immune system. The β cells, which are located in the pancreas, regulate blood glucose levels. The lack of insulin production requires administration of insulin. This is accomplished by insulin injections. Even though the treatment methods have been improve

Effect of experimental complex III deficiency on respiratory chain assembly and function

The assembly of respiratory chain complexes in the mitochondrial inner membrane requires specific factors. Once assembled to form a mature functional complex, complex III (CIII) is a dimer consisting of two monomers, each with eleven subunits. To date, seven assembly factors for CIII are known, of which BCS1L incorporates the Rieske iron-sulfur protein (RISP) in the last stage of the assembly. The

Statistical Analysis of Crests and Maxima in Gaussian Seas

An important problem in ocean engineering is to find distributions for characteristic wave parameters. For wind-generated water waves at deep water, a Gaussian distribution for the wave-surface elevation is considered a reasonable model. Within the Gaussian assumption, extensions of Rice's formula can be applied to formulate explicit expressions for the distributions in the ergodic, or Palm, sense