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Trisomy 8 (+8) is a common cytogenetic aberration in acute myeloid leukemia (AML); however, the impact of +8 in pediatric AML is largely unknown. We retrospectively investigated 609 patients from the NOPHO-AML database to determine the clinical and cytogenetic characteristics of +8 in pediatric AML and to investigate its prognostic impact. Complete cytogenetic data were available in 596 patients (
We sought to identify novel pharmacogenetic markers associated with cardiovascular outcomes in patients with hypertension on antihypertensive therapy. We genotyped a 1:4 case:control cohort (n=1345) on the Illumina HumanCVD Beadchip from the INternational VErapamil SR-Trandolapril STudy (INVEST), where participants were randomized to a -blocker strategy or a calcium channel blocker strategy. Genom
Häktning är ett straffprocessuellt tvångsmedel som kan användas vid utredning av misstänkt brottslighet. Häktning kan under vissa förutsättningar kombineras med restriktioner, med följd att den häktade isoleras från omvärlden. Det svenska häktningsinstitutet har sedan tidigt 90-tal återkommande erhållit internationell kritik. Kritiken har bland annat avsett att det saknas tidsgränser för hur längeRemand is a coercive measure which may be used while investigating a suspected crime. Remand may, under certain conditions, be combined with restrictions, resulting in the detainee being isolated from the outside world. The Swedish remand institute has received international criticism since the early 1990s. The criticism has, among other things, been related to the lack of time limits for how long
Mjukvaror och produktansvarslagen - en komparativ studie är en komparativ studie som belyser den svenska och danska produktansvarslagstiftningens tillämpligheten på mjukvaror och vad för problematik som uppstår om gällande lagstiftning inte omfattar mjukvaror. Tillämpligheten har diskuterats utifrån analyser av förarbeten och hur frågan har diskuterats i litteraturen. Slutligen förs ett resonemangMjukvaror och produktansvarslagen - en komparativ studie is a comparative study that illustrate the applicability of the Danish and Swedish Product Liability Act and what problems arise if the current legislation does not include software. The applicability has been discussed based on analyzes of preliminary work and how the issue has been discussed in the literature. Lastly, there is a discussion
Sverige har en lång tradition av en flexibel arbetsmarknad där arbetstagare fritt kunnat förflytta sig mellan offentlig och privat sektor. Övergångar av detta slag är i många delar positivt och genererar ett erfarenhetsutbyte som är till gagn för båda sektorer. I samband med övergång från anställning i offentlig till privat verksamhet kan emellertid så kallad svängdörrsproblematik uppstå. Denna prSweden has a long tradition of a flexible labor market where employees have been able to freely move between the public and private sectors. Transitions of this kind are largely positive and generate an exchange of experience that benefits both sectors. However, transitions from employment in the public sector to the private sector can give rise to what is known as the revolving door problem. This
The Swedish age of criminal responsibility means that children under 15 who commit offences cannot be sentenced to any penalty. There is, however, a process in § 38 LUL that can determine whether a child under 15 has commit-ted a serious crime, called an evidentiary proceeding. At the time of its crea-tion, the purpose of an evidentiary proceeding was to provide the child wel-fare authorities with
On July 22, 2022, a crown witness system was introduced with the aim of increasing prosecution rates and breaking the prevailing culture of silence. This system includes a basis for sentence reduction regarding participation in the investigation of another's criminal activity. The idea behind the crown witness system is to increase incentives for suspects to cooperate in order to solve more se
On 1 July 2022, the Swedish Act (1988:254) on the Prohibition of Knives and Other Dangerous Objects (the Swedish Knife Act), which criminalizes possession of knives and other dangerous objects in public places, was amended. Through the amendment, four criteria were introduced to the statutory text, which are to be given particular consideration when assessing whether a violation of the law is to b
Title: The art of combining availability and exclusivity – A dialectical analysis of the tension between premium and luxury Seminar date: 2025-06-05 Course: FEKH29, Business Administration: Degree Project in Marketing, Undergraduate level, 15 credits Authors: Pontus Sölve, Hannes Hemgren, Julia Johansson Mozaffari Advisor: Jon Bertilsson Key words: Brand, Premium, Luxury, Masstige, New luxu
Title: Between few rules and strong culture: a qualitative study on culture and identity in a knowledge-intensive organization without explicit formalities. Seminar date: 3rd of June, 2025. Course: FEKH49, Degree Project Undergraduate Level, Business Administration, Undergraduate level, 15 ECTS. Authors: Klara Andersson, Julia Hesslevik & Sophie Linder. Advisor: Stefan Sveningsson. Keywords:
On the first of July 2018, Sweden made a drastic change to its rape provision, by adopting a new legislation, commonly referred to as the ”Consent Law”. Sweden’s neighboring country, Denmark, adopted its own version of the Consent Law a couple of years later, on the first of January 2021. The newely change of the Swedish and Danish penal codes have been an important step torwards reducing rap
År 2008 brakade den finansiella marknaden samman och följdes av en recession världen över som vi till viss del fortfarande brottas med. OTC-derivat, ett skräddarsytt bilateralt finansiellt instrument, har i finanskrisens efterdyningar beskyllts vara en av bovarna i dramat. Särskilt tros OTC-derivaten ha bidragit till en icke-transparens på marknaden som gjorde det omöjligt att både förutse och förIn 2008 the financial market collapsed and what followed was a worldwide recession which the market has yet to fully recover from. OTC-derivatives, which are tailor-made bilateral financial instruments, have in the aftermath of the collapse been accused of being one of the culprits. More specifically, OTC-derivatives are believed to have contributed to the opaque financial market that made it impo
Idag återfinns sexistiska kommentarer på sociala medieplattform, trots att företagen bakom har regler för vad som får publiceras. Sexism är ett strukturellt problem som kan påverka kvinnor negativt, både fysiskt och psykiskt och kan leda till självcensur. Ge- nom en kvalitativ textanalys syftar denna uppsats att testa om tre principer kan användas för att analysera om sexistiska kommentarer från FToday, sexist comments can be found on social media platforms, despite social media companies having rules on what is allowed to be published. Sexism is a structural prob- lem which can negatively affect women, both physically and mentally, and could lead to self-censorship. Through a qualitative text analysis, this essay aims to investigate whether sexist comments from Facebook and Instagram are
On July 1 this year, a new crime for involving a minor in crime will be introduced in Chapter 16, Section 5 a of the Swedish Penal Code. In the government bill, the purpose of the new criminalization is described as protecting society from young people being drawn into criminal networks. For a penal provision to be considered justified, there are several criminalization principles to which it mus
Until July 1, 2018, Swedish legislation lacked a general remedy for delays in the authorities’ handling of cases. With the introduction of section 12 of the Public Administration Act the remedy, often referred to as the delay action, came to change the Swedish Migration Agency’s routine handling of citizenship applications. Authorities would henceforth not be able to act passively in the handling
The EU Market Abuse Regulation, MAR, entered into force in July 2016 and is a central framework in the field of stock-market law. The regulation provides a uniform definition of the concept of inside information that has a significant role in both the application and understanding of several provisions in the regulation. These aim to create transparency in the market, as well as to combat various
During the period of June 2011 until July 2013, the thorax surgeon Paolo Macchiarini carried out four transplants with synthetic trachea on three different patients at the Karolinska University Hospital. These transplants entailed the later death of all the patients. Macchiarini was notified suspicion of a crime in June 2016, causing another's death, gross felony, alternatively, causing bodily
The Market Abuse Regulation (MAR) came into force on 3 July 2016 and replaced the previous Market Abuse Directive (MAD). Among the obligations regulated by MAR, there is a duty for the issuer to publish inside information. According to article 17 (1) MAR, the issuer is obligated to inform the public concerning inside information directly affecting the issuer as soon as possible. The issuer must al
