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The major bactericidal activity of human seminal plasma is zinc-dependent and derived from fragmentation of the semenogelins.

One of the major roles of seminal plasma is to provide antimicrobial protection for the spermatozoa in the female reproductive tract. We found that the bactericidal activity of seminal plasma was highest after resolution of the seminal clot and that this antibacterial activity subsequently became greatly diminished. The antibacterial activity was derived from peptides generated by fragmentation of

ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation.

The balance between self-renewal and differentiation is crucial for the maintenance of hematopoietic stem cells (HSCs). Whereas numerous gene regulatory factors have been shown to control HSC self-renewal or drive their differentiation, we have relatively few insights into transcription factors that serve to restrict HSC differentiation. In the present work, we identify ETS (E-twenty-six)-related

Land-atmosphere exchange of methane from soil thawing to soil freezing in a high-Arctic wet tundra ecosystem

The land-atmosphere exchange of methane (CH4) and carbon dioxide (CO2) in a high-Arctic wet tundra ecosystem (Rylek ae rene) in Zackenberg, north-eastern Greenland, was studied over the full growing season and until early winter in 2008 and from before snow melt until early winter in 2009. The eddy covariance technique was used to estimate CO2 fluxes and a combination of the gradient and eddy cova

Gaze behavior in face-to-face interaction : A cross-cultural investigation between Japan and The Netherlands

Previous research suggests a pattern of gaze avoidance in East Asian compared with Western cultures. Yet, recent eye-tracking studies of face-to-face conversation do not corroborate this. More generally, differences in nonverbal communication and analytic versus holistic strategies have been described between East Asian and Western cultures. Using wearable eye-tracking technology and an automated

Insiderinformation och nyhetskanalers rapportering om emittenter – En utredning av definitionen och hanteringen av insiderinformation i MAR

The EU Market Abuse Regulation, MAR, entered into force in July 2016 and is a central framework in the field of stock-market law. The regulation provides a uniform definition of the concept of inside information that has a significant role in both the application and understanding of several provisions in the regulation. These aim to create transparency in the market, as well as to combat various

Oaktsamt orsakande och relevans - En rättsdogmatisk studie om gärningsculpa i vården

During the period of June 2011 until July 2013, the thorax surgeon Paolo Macchiarini carried out four transplants with synthetic trachea on three different patients at the Karolinska University Hospital. These transplants entailed the later death of all the patients. Macchiarini was notified suspicion of a crime in June 2016, causing another's death, gross felony, alternatively, causing bodily

Skyldigheten att offentliggöra insiderinformation - Särskilt en utredning av rekvisitet så snart som möjligt i artikel 17(1) MAR

The Market Abuse Regulation (MAR) came into force on 3 July 2016 and replaced the previous Market Abuse Directive (MAD). Among the obligations regulated by MAR, there is a duty for the issuer to publish inside information. According to article 17 (1) MAR, the issuer is obligated to inform the public concerning inside information directly affecting the issuer as soon as possible. The issuer must al

Krigets dolda brott mot mänskligheten - En studie om kvinnors rättsliga skydd mot våldtäkter i väpnade konflikter med särskilt fokus på The Prosecutor v. Bosco Ntaganda

On 8 July 2019, ICC Trial Chamber VI found Congolese commander Bosco Ntaganda guilty for rape as a crime against humanity. In March 2021, the appealed verdict was upheld by the Appeals Chamber of the ICC, making it the first conviction in history to sentence someone as individually criminally responsible for rape as a crime against humanity. Sexual violence in armed conflicts has been a highly to

Vilket pris har klimatet? – En undersökning av skattemässig behandling av utgifter hänförliga till klimatkompensation

Syftet med denna uppsats är att undersöka hur ett aktiebolags utgifter hänförliga till klimatkompensation behandlas vid inkomstbeskattning. För att uppnå detta syfte tillämpas en traditionell rättsdogmatisk metod. Lagtexten innehåller inte någon särskild reglering avseende avdragsrätt för klimatkompensationsutgifter, vilket resulterar i att bedömningen baseras på de allmänna reglerna om avdragsrätThe purpose of this essay is to investigate how limited liability companies’ expenses related to carbon offset are treated in the event of income taxation. To accomplish this purpose a legal dogmatic method has been applied. The law contains no specific regulation concerning the deductibility of costs attributable to carbon offset and, as a result, the assessment is made based on the general rules

Central motpartsclearing av OTC-derivat

År 2008 brakade den finansiella marknaden samman och följdes av en recession världen över som vi till viss del fortfarande brottas med. OTC-derivat, ett skräddarsytt bilateralt finansiellt instrument, har i finanskrisens efterdyningar beskyllts vara en av bovarna i dramat. Särskilt tros OTC-derivaten ha bidragit till en icke-transparens på marknaden som gjorde det omöjligt att både förutse och förIn 2008 the financial market collapsed and what followed was a worldwide recession which the market has yet to fully recover from. OTC-derivatives, which are tailor-made bilateral financial instruments, have in the aftermath of the collapse been accused of being one of the culprits. More specifically, OTC-derivatives are believed to have contributed to the opaque financial market that made it impo

Svängdörrsproblematik och intressekonflikter - En analys av förslaget om övergångsrestriktioner i offentlig verksamhet

Sverige har en lång tradition av en flexibel arbetsmarknad där arbetstagare fritt kunnat förflytta sig mellan offentlig och privat sektor. Övergångar av detta slag är i många delar positivt och genererar ett erfarenhetsutbyte som är till gagn för båda sektorer. I samband med övergång från anställning i offentlig till privat verksamhet kan emellertid så kallad svängdörrsproblematik uppstå. Denna prSweden has a long tradition of a flexible labor market where employees have been able to freely move between the public and private sectors. Transitions of this kind are largely positive and generate an exchange of experience that benefits both sectors. However, transitions from employment in the public sector to the private sector can give rise to what is known as the revolving door problem. This

Barn i domstol – proportionerlig åtgärd eller förhastad nödlösning? En undersökning av 2023 års ändring i bevistaleinstitutet utifrån ett barnrättsperspektiv

The Swedish age of criminal responsibility means that children under 15 who commit offences cannot be sentenced to any penalty. There is, however, a process in § 38 LUL that can determine whether a child under 15 has commit-ted a serious crime, called an evidentiary proceeding. At the time of its crea-tion, the purpose of an evidentiary proceeding was to provide the child wel-fare authorities with

Vem vågar bryta tysta leken? - En rättsvetenskaplig studie om kronvittnessystemets inverkan på den tilltalades rättssäkerhet

On July 22, 2022, a crown witness system was introduced with the aim of increasing prosecution rates and breaking the prevailing culture of silence. This system includes a basis for sentence reduction regarding participation in the investigation of another's criminal activity. The idea behind the crown witness system is to increase incentives for suspects to cooperate in order to solve more se

Straffskärpning i teori och praktik - Om hur skärpningarna av knivlagen kommit att tillämpas i praxis

On 1 July 2022, the Swedish Act (1988:254) on the Prohibition of Knives and Other Dangerous Objects (the Swedish Knife Act), which criminalizes possession of knives and other dangerous objects in public places, was amended. Through the amendment, four criteria were introduced to the statutory text, which are to be given particular consideration when assessing whether a violation of the law is to b

Konsten att kombinera tillgänglighet och exklusivitet – En dialektisk analys av spänningen mellan premium och lyx

Title: The art of combining availability and exclusivity – A dialectical analysis of the tension between premium and luxury Seminar date: 2025-06-05 Course: FEKH29, Business Administration: Degree Project in Marketing, Undergraduate level, 15 credits Authors: Pontus Sölve, Hannes Hemgren, Julia Johansson Mozaffari Advisor: Jon Bertilsson Key words: Brand, Premium, Luxury, Masstige, New luxu