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Disputationer 2004

Marcus GladerInnovation Markets and Competition Analysis- EU competition law and US antitrust lawDatum för disputation: lördagen den 11 december 2004Fakultetsopponent: senior visiting research fellow John Temple, Oxford universitet, EnglandÄmne: civilrättAbstractInnovation issues are increasingly highlighted in public policy, including competition policy. Not only is innovation a major factor behi

https://www.jur.lu.se/forskning/disputationer/disputationer-2004 - 2025-09-15

Common themes and challenges in hemophilia care : a multinational perspective

OBJECTIVE: To identify ways that provision of hemophilia care can be maximized at the local level, irrespective of available resources or cultural or geographic challenges.METHODS: The SHIELD group used its multinational experience to share examples of local initiatives that have been employed to deliver optimal hemophilia care.RESULTS: The examples were reviewed and categorized into four key them

Assessing the Potential of Ozonation in the Production of Water for Injection from a Sustainability, Legal, Cost and Feasibility Perspective

Water for Injection (WFI) is a critical utility in pharmaceutical manufacturing, traditionally produced through an energy-intensive distillation process. This thesis investigates the feasibility of a more sustainable alternative, ambient WFI production using membrane-based purification technologies combined with ozonation in the storage and distribution loop. Conducted in collaboration with AstraZ

Discovery of novel AQP3-inhibitors

Vatten är nödvändigt för att den mänskliga kroppen ska fungera. För att vattnet ska kunna transporteras in och ut ur cellerna behöver det komma igenom cellmembranet, vilket det bland annat gör via en särskild klass av proteiner som fungerar som vattenkanaler – akvaporinerna. Akvaporiner finns överallt i vår kropp och är viktiga för många biologiska funktioner såsom metabolism och återfuktning av hAquaporins (AQPs) are a family of transmembrane proteins, mainly mediating water transport over the cell membrane in various parts of the body. The aquaporins AQP3 and AQP7 are both part of the subfamily aquaglyceroporins, which apart from water conduct small non-polar solutes such as glycerol. AQP3 overexpression or malfunction has been connected to skin and lung cancer and potential AQP3 inhibit

“We all live with many selves at once – that’s the true nature of life.” - Exploring Tibetan Identities through Audience Study on Native Tibetan Film Balloon (2019)

This thesis explores the construction and negotiation of Tibetan identities through the lens of native Tibetan cinema, with a focus on Pema Tseden’s Balloon (2019). Drawing on theories of identity as construction, cultural hybridity, and minor cinema, the study examines how cinematic narratives and audience interpretations intersect to produce a nuanced understanding of Tibetan identities in conte

Greenhouse Gas Emissions and Energy Payback Time for multi- and mono-Si Photovoltaic Systems - A Study on Solar Energy from Photovoltaic Systems Located in Sweden

Solceller – en miljövänlig energikälla? Miljöförstöring i form av växthusgasutsläpp är en gigantisk utmaning som mänskligheten står inför och vi måste agera NU! Solceller innebär en fantastisk möjlighet att utvinna stora mängder “ren” energi från solen. Men hur miljövänliga är egentligen solceller och är det ett effektivt alternativ i Sverige? Varje timme träffas Jorden av tillräckligt mycket eClimate change is one of the greatest environmental challenges at the present time and is currently an issue affecting the entire global population. Alternative renewable energy sources are vital to be able to deal with this challenge. Solar energy is one of the most promising renewable energy sources and is therefore also one of the fastest growing industries in this field. However, solar energy

Tungmetaller i en sedimentkärna från en sjö norr om polcirkeln-möjliga orsaker till haltvariationer i vertikalled

Hur har föroreningar förändrats över tiden i nordligaste delen av Sverige? Om höga halter tungmetaller finns, vilka kan vara orsakerna till dessa? En resa från södra Skåne till norra Lappland har visat att de flesta metaller i sedimentet från en sjö har minskat på senare år, Hg samt Arsenik har dock ökat. Detta beror troligtvis på minskad användning av fossila bränslen samt gruvdriften i norr.Changes in the accumulation of heavy metals (Cd, Cu, Hg, Fe, Mn, Ni, Pb, Zn), arsenic (As), and selenium (Se) in sediment of pristine lake in northern Sweden were studied by making measurements at different depths in a sediment core. The sediment core was extracted from the deepest part of the lake Sautusjärvi, close to the village Jukkasjärvi. The sediment samples were transported in a cooler to

The Establishment of Macrobenthic Faunal Communities in Planted Mangroves of Increasing Age

Mangroveskogens ekosystem är ett tropiskt kustsamhälle bebott av organismer anpassade till den stressfulla miljön i tidvattenszonen. Mangroveskogen har på senare år blivit erkänd för de viktiga ekosystemtjänsterna den erbjuder. Trotts detta hotas den av mänskliga aktiviteter, och en tredjedel av världens naturliga mangroveskog uppskattas redan ha gått förlorad. Ansträngningar har gjorts för att beThe mangrove ecosystem is a tropical coastal community inhabited by organisms adapted to the stressful environment of the tidal zone. Mangrove ecosystems has in recent years been noted for the important ecosystem services they offer. Still, they are threatened by anthropogenic activities and it has been estimated that a third of the world’s natural mangrove cover has already been lost. Efforts hav

Land Matters : Agrofuels, Unequal Exchange, and Appropriation of Ecological Space

As a global society we are entering an era where land areas and land-based resources are coming to the fore once again for capital accumulation and economic growth, for the first time since the end of the 18th century when Malthus forecasted a contradiction between population growth and agricultural output. That constraint on economic growth, imposed by limited land areas, was overcome by the comb

Improved soil hydrological modeling with the implementation of salt-induced freezing point depression in CoupModel : Model calibration and validation

Soil freezing/thawing is an important mechanism to control soil water and heat redistribution in mid-to-high latitudes. Salt in the agricultural soil from mid-to-high latitudes can alter characteristics of soil freezing/thawing cycle and then affect soil thermal and hydrological processes in winter and finally cause salinization in spring. To quantify the impacts of soil salinization on soil water

Estimating the Legacy Effect of Post-Cutting Shelterbelt on Crop Yield Using Google Earth and Sentinel-2 Data

Shelterbelts (or windbreaks) can effectively improve the microclimate and soil conditions of adjacent farmland and thus increase crop yield. However, the individual contribution of these two factors to yield changes is still unclear since the short-term effect from the microclimate and the accumulated effect from the soil jointly affect crop yield. The latter (soil effect) is supposed to remain af

Activation of Hormone-sensitive Lipase Requires Two Steps, Protein Phosphorylation and Binding to the PAT-1 Domain of Lipid Droplet Coat Proteins

Lipolysis is an important metabolic pathway controlling energy homeostasis through degradation of triglycerides stored in lipid droplets and release of fatty acids. Lipid droplets of mammalian cells are coated with one or more members of the PAT protein family, which serve important functions in regulating lipolysis. In this study, we investigate the mechanisms by which PAT family members, perilip

Heparan sulfate 3-O-sulfotransferase isoform 5 generates both an antithrombin-binding site and an entry receptor for herpes simplex virus, type 1

Heparan sulfate 3-O-sulfotransferase transfers sulfate to the 3-OH position of a glucosamine residue of heparan sulfate (HS) to form 3-O-sulfated HS. The 3-O-sulfated glucosamine residue contributes to two important biological functions of HS: binding to antithrombin and thereby carrying anticoagulant activity, and binding to herpes simplex viral envelope glycoprotein D to serve as an entry recept

APPLICATION OF DIFFERENT HYDROLOGIC MODELS IN FLASH FLOODS SIMULATION

In recent years, the flash flood occurs frequently and intensively. It has become a world-wide focus in the field of disaster prevention and mitigation. The flash flood critical rainfall determination method, flash floods forecasting model and experience forecasting method are the most commonly used methods. This study focused on the application of hydrological models for flash floods simulation.T

Stakeholder-based Brand Equity (SBBE) : A qualitative study of its development through firm-stakeholder interactions in emerging markets

This thesis challenges the prevailing firm-consumer/customer-centric and dyadic perspective that prevails within the brand equity literature, which is based on a linear, straightforward stimulus-response approach to the creation of brand value. Leaning on the literature on interorganisational relationships, stakeholder theory, market emergence/market driving, and firm internationalisation, which s

The risk of carbon leakage in global climate agreements

Although climate change and international trade are interdependent, policy-makers often address the two topics separately. This may inhibit progress at the intersection of climate change and trade and could present a serious constraint for global climate action. One key risk is carbon leakage through emission outsourcing, i.e. reductions in emissions in countries with rigorous climate policies bei