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A 60 000 year Greenland stratigraphic ice core chronology
The Greenland Ice Core Chronology 2005 (GICC05) is a time scale based on annual layer counting of high-resolution records from Greenland ice cores. Whereas the Holocene part of the time scale is based on various records from the DYE-3, the GRIP, and the NorthGRIP ice cores, the glacial part is solely based on NorthGRIP records. Here we present an 18 ka extension of the time scale such that GICC05
The Virtual Museum of the Western Han Dynasty: 3D Documentation and Interpretation
This project, aimed to the digital documentation of archaeological sites, artifacts and cultural relics of the Western Han Dynasty, started in 2008. The anticipated outcome will be the creation of a virtual museum, based on collaborative environments, dedicated to the Western Han Dynasty and able to integrate new archaeological datasets coming from fieldwork activities (most part of them unpublish
Expression of Epstein-Barr Virus-Encoded LMP1 and hTERT Extends the Life Span and Immortalizes Primary Cultures of Nasopharyngeal Epithelial Cells
U-Pb baddeleyite and zircon ages of 2040 Ma, 1650 Ma and 885 Ma on dolerites in the West African Craton (Anti-Atlas inliers): Possible links to break-up of Precambrian supercontinents
Precambrian inliers of the Anti-Atlas belt in the southern part of Morocco contain numerous dolerite dyke and sill swarms which were previously poorly dated. Four dykes and two sills dated by the U-Pb TIMS method on baddeleyite and zircon provide the first steps toward a magmatic 'barcode' for the West African Craton (WAC) and constraints on the timing of breakup of the WAC from Precambrian superc
Anthropogenic transformation of Yangtze Plain freshwater lakes: patterns, drivers and impacts
Importing political polarization? The electoral consequences of rising trade exposure
Has rising import competition contributed to the polarization of US politics? Analyzing multiple measures of political expression and results of congressional and presidential elections spanning the period 2000 through 2016, we find strong though not definitive evidence of an ideological realignment in trade- exposed local labor markets that commences prior to the divisive 2016 US presidential ele
A compendium answering 150 questions on COVID-19 and SARS-CoV-2
Responses of soil extracellular enzyme activities and microbial community properties to interaction between nitrogen addition and increased precipitation in a semi-arid grassland ecosystem
Both atmospheric nitrogen (N) deposition and precipitation can strongly impact below-ground biogeochemical processes. Soil extracellular enzymes activities (EEAs) and microorganisms are considered as the key agents in ecosystem nutrient cycling. However, how the interaction between increasing N deposition and precipitation may affect soil EEAs and microbes remain poorly understood. In a 5-year fie
Coupled water transport and heat flux in seasonally frozen soils : uncertainties identification in multi-site calibration
Groundwater depletion estimated from GRACE : A challenge of sustainable development in an arid region of Central Asia
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors
ADAM12/syndecan-4 signaling promotes beta(1) integrin-dependent cell spreading through protein kinase C alpha and RhoA
The ADAMs (a disintegrin and metalloprotease) comprise a large family of multidomain proteins with cell-binding and metalloprotease activities. The ADAM12 cysteine-rich domain (rADAM12-cys) supports cell attachment using syndecan-4 as a primary cell surface receptor that subsequently triggers beta(1) integrin-dependent cell spreading, stress fiber assembly, and focal adhesion formation. This proce
Importing Political Polarization? The Electoral Consequences of Rising Trade Exposure
Has rising import competition contributed to the polarization of U.S. politics? Analyzing multiple measures of political expression and results of congressional and presidential elections spanning the period 2000 through 2016, we find strong though not definitive evidence of an ideological realignment in trade-exposed local labor markets that commences prior to the divisive 2016 U.S. presidential
Isolation of Coxsackievirus A24 variant from patients with hemorrhagic conjunctivitis in Cuba, 2008-2009
BACKGROUND: An outbreak of acute hemorrhagic conjunctivitis occurred in Cuba in 2008 and 2009.OBJECTIVE: To determinate the etiological agent associated with the Cuban outbreaks of acute hemorrhagic conjunctivitis during 2008 and 2009.STUDY DESIGN: Conjunctival swabs and/or faecal samples from 382 patients with clinical diagnosis suggestive of acute hemorrhagic conjunctivitis were subject to viral
Impairment of DNA replication within one cell cycle after seeding of cells in the presence of a polyamine biosynthesis inhibitor
The IgD-binding domain of the Moraxella IgD-binding protein MID (MID962-1200) activates human B cells in the presence of T cell cytokines.
Moraxella catarrhalis immunoglobulin D (IgD)-binding protein (MID) is an outer membrane protein with specific affinity for soluble and cell-bound human IgD. Here, we demonstrate that mutated M. catarrhalis strains devoid of MID show a 75% decreased activation of human B cells as compared with wild-type bacteria. In contrast to MID-expressing Moraxella, the MID-deficient Moraxella mutants did not b
The Epidemiology of Intracerebral Haemorrahge. Risk factors and prognosis
Preventable breast cancer is postmenopausal
Breast cancer incidence has markedly increased in Western countries for reasons that are not entirely understood. We characterized periodic and age-specific incidence trends of breast cancer in immigrants who migrated from low incidence areas to Sweden. The incidence in immigrants was compared to that in native Swedes and standardized incidence ratios (SIRs) were calculated, based on the Swedish F
To facilitate a fair bioeconomy transition, stronger regional-level linkages are needed
The great hopes in Brussels that a circular bioeconomy will help bridge the growing divide between urban and rural areas and allow the hinterlands to prosper from ‘green growth’ are addressed in this article, which reflects on insights from three Nordic case studies of brown, green and blue biomass use at different levels of technology readiness. A closer examination of the forward, backward, fisc
