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Public health can be immediately and substantially improved by policies that also mitigate climate change over the longer term. However, implementation of these policies has been slowed at least in part by doubts and lack of awareness of these health co-benefits. To address this barrier to progress, we demonstrate how an illustrative set of interventions led to environmental, health, and economic

Obesity represents a global health challenge, with a critical and urgent need for long-term, sustainable management strategies. Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. At first approved for the treatment of type 2 diabetes mellitus, tirzepatide represents one of the latest clinically approved and commercia

Precambrian inliers of the Anti-Atlas belt in the southern part of Morocco contain numerous dolerite dyke and sill swarms which were previously poorly dated. Four dykes and two sills dated by the U-Pb TIMS method on baddeleyite and zircon provide the first steps toward a magmatic 'barcode' for the West African Craton (WAC) and constraints on the timing of breakup of the WAC from Precambrian superc

Background Evidence for treating infantile colic with acupuncture is contradictory. Aim To evaluate and compare the effect of two types of acupuncture versus no acupuncture in infants with colic in public child health centres (CHCs). Methods A multicentre, randomised controlled, single-blind, three-armed trial (ACU-COL) comparing two styles of acupuncture with no acupuncture, as an adjunct to stan

Moraxella catarrhalis immunoglobulin D (IgD)-binding protein (MID) is an outer membrane protein with specific affinity for soluble and cell-bound human IgD. Here, we demonstrate that mutated M. catarrhalis strains devoid of MID show a 75% decreased activation of human B cells as compared with wild-type bacteria. In contrast to MID-expressing Moraxella, the MID-deficient Moraxella mutants did not b

Has rising import competition contributed to the polarization of US politics? Analyzing multiple measures of political expression and results of congressional and presidential elections spanning the period 2000 through 2016, we find strong though not definitive evidence of an ideological realignment in trade- exposed local labor markets that commences prior to the divisive 2016 US presidential ele

Both atmospheric nitrogen (N) deposition and precipitation can strongly impact below-ground biogeochemical processes. Soil extracellular enzymes activities (EEAs) and microorganisms are considered as the key agents in ecosystem nutrient cycling. However, how the interaction between increasing N deposition and precipitation may affect soil EEAs and microbes remain poorly understood. In a 5-year fie

This project, aimed to the digital documentation of archaeological sites, artifacts and cultural relics of the Western Han Dynasty, started in 2008. The anticipated outcome will be the creation of a virtual museum, based on collaborative environments, dedicated to the Western Han Dynasty and able to integrate new archaeological datasets coming from fieldwork activities (most part of them unpublish

The early Cambrian succession at Chengjiang contains the most diverse Cambrian fossil assemblage yet described, and contributes significantly to our understanding of the diversification of metazoans in the Cambrian “explosion”. The Cambrian Period occupies a transitional episode of global ocean chemistry, following the oxygenation of the surface ocean and of shallow marine environments during the

Burgess Shale-type biotas occur globally in the Cambrian record and offer unparalleled insight into the Cambrian explosion, the initial Phanerozoic radiation of the Metazoa. Deposits bearing exceptionally preserved soft-bodied fossils are unusually common in Cambrian strata; more than 40 are now known. The well-documented decline of soft-bodied preservation following the Middle Cambrian represents

Governed directly by the US from the Battle of Okinawa in 1945 until its reversion to Japan in 1972, the island of Okinawa hosts the majority of US military bases in Japan despite comprising only a fraction of a percent of the total land area. The central government in Tokyo has refused to countenance revision of the status quo in the face of increasing local opposition, including mass protests an

The recording and verbatim transcription of interviews is often considered to be one of the more tedious but necessary aspects of the in-depth qualitative research process. While transcription is undoubtedly a necessary methodological tool for researchers focusing specifically on discourse and language, it has also been widely adopted by researchers across the social sciences, and is sometimes adv

Increasing global production fragmentation allows for emission displacement, which may counteract advanced nation’s domestic reductions of production-related carbon emissions. Consequently, input-output analysis has become a common tool to measure countries’ carbon footprint and emission trade balances based on national consumption instead of domestically produced CO2 emissions. Nevertheless, trad