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Effects of polyamine pool manipulation on genes expressed during the cell cycle

Popular Abstract in Swedish En cell förökar sig genom delning. Före delningen måste den växa och fördubbla cellinnehållet för att det ska finnas material till två nya celler. En cellcykel är de händelser som sker från det en cell delat sig tills den delar sig igen [Fig 1]. En cellcykel kan delas in i fyra faser som cellen måste genomgå innan den är mogen att dela sig. Under första fasen, G1, tillvThe polyamines - putrescine, spermidine and spermine - are polycations found within cells. They have been shown to be essential for optimal cell proliferation and cell survival. Cells maintain their polyamine levels in a well-regulated system involving biosynthesis, catabolism and uptake/excretion. The biosynthetic enzymes - ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (Ado

SME creation facilitation process at Universities

Much research on SMEs is aimed at researching SMEs after the fact that they have become SMEs. However all SMEs as well as larger companies start as an idea in the head or heads of one or many persons - the prospective entrepreneurs. The purpose of this paper is to investigate how SMEs can be created by transforming ideas into real companies. More specifically we will investigate if and how Univers

A 60 000 year Greenland stratigraphic ice core chronology

The Greenland Ice Core Chronology 2005 (GICC05) is a time scale based on annual layer counting of high-resolution records from Greenland ice cores. Whereas the Holocene part of the time scale is based on various records from the DYE-3, the GRIP, and the NorthGRIP ice cores, the glacial part is solely based on NorthGRIP records. Here we present an 18 ka extension of the time scale such that GICC05

The Virtual Museum of the Western Han Dynasty: 3D Documentation and Interpretation

This project, aimed to the digital documentation of archaeological sites, artifacts and cultural relics of the Western Han Dynasty, started in 2008. The anticipated outcome will be the creation of a virtual museum, based on collaborative environments, dedicated to the Western Han Dynasty and able to integrate new archaeological datasets coming from fieldwork activities (most part of them unpublish

Early Cambrian oxygen minimum zone-like conditions at Chengjiang

The early Cambrian succession at Chengjiang contains the most diverse Cambrian fossil assemblage yet described, and contributes significantly to our understanding of the diversification of metazoans in the Cambrian “explosion”. The Cambrian Period occupies a transitional episode of global ocean chemistry, following the oxygenation of the surface ocean and of shallow marine environments during the

Burgess shale-type biotas were not entirely burrowed away

Burgess Shale-type biotas occur globally in the Cambrian record and offer unparalleled insight into the Cambrian explosion, the initial Phanerozoic radiation of the Metazoa. Deposits bearing exceptionally preserved soft-bodied fossils are unusually common in Cambrian strata; more than 40 are now known. The well-documented decline of soft-bodied preservation following the Middle Cambrian represents

Effect of minimal acupuncture for infantile colic : A multicentre, three-armed, single-blind, randomised controlled trial (ACU-COL)

Background Evidence for treating infantile colic with acupuncture is contradictory. Aim To evaluate and compare the effect of two types of acupuncture versus no acupuncture in infants with colic in public child health centres (CHCs). Methods A multicentre, randomised controlled, single-blind, three-armed trial (ACU-COL) comparing two styles of acupuncture with no acupuncture, as an adjunct to stan

A global survey of emergency department responses to the COVID-19 pandemic

Introduction: Emergency departments (ED) globally are addressing the coronavirus disease 2019 (COVID-19) pandemic with varying degrees of success. We leveraged the 17-country, Emergency Medicine Education & Research by Global Experts (EMERGE) network and non-EMERGE ED contacts to understand ED emergency preparedness and practices globally when combating the COVID-19 pandemic. Methods: We elect

Importing Political Polarization? The Electoral Consequences of Rising Trade Exposure

Has rising import competition contributed to the polarization of U.S. politics? Analyzing multiple measures of political expression and results of congressional and presidential elections spanning the period 2000 through 2016, we find strong though not definitive evidence of an ideological realignment in trade-exposed local labor markets that commences prior to the divisive 2016 U.S. presidential

Isolation of Coxsackievirus A24 variant from patients with hemorrhagic conjunctivitis in Cuba, 2008-2009

BACKGROUND: An outbreak of acute hemorrhagic conjunctivitis occurred in Cuba in 2008 and 2009.OBJECTIVE: To determinate the etiological agent associated with the Cuban outbreaks of acute hemorrhagic conjunctivitis during 2008 and 2009.STUDY DESIGN: Conjunctival swabs and/or faecal samples from 382 patients with clinical diagnosis suggestive of acute hemorrhagic conjunctivitis were subject to viral

An Improved Spatial Downscaling Procedure for TRMM 3B43 Precipitation Product Using Geographically Weighted Regression

Precipitation data at high spatio-temporal resolution are essential for hydrological, meteorological, and ecological research in local basins and regions. The coarse spatial resolution (0.25°) of Tropical Rainfall Measuring Mission (TRMM) 3B43 product is insufficient for practical requirements. In this paper, a multivariable geographically weighted regression (GWR) downscaling method was developed

Turning the tanker? Exploring the preconditions for change in the global petrochemical industry

Meeting the goals set out in the Paris Agreement will require rapid and deep reductions of greenhouse gas emissions (GHG) across all sectors of the global economy. Like all major societal transformations, this climate transition will impact both social and technical aspects of society and, depending on how it evolves, will reallocate social and economic benefits and costs differently. Recognising

Reclaiming the Right to the City : De-commodification of Shopping Malls in Insurgent Hong Kong

According to Lefebvre, modern capitalism has led to the commodification of urban life. Even though commodification has taken multiple distinct forms across the urban fabric, it could be argued that no urban feature is more representative of the proliferation of exchange values than shopping malls. Despite being privately owned and managed, commercialised and highly securitised, shopping malls have

Informing the SWAT model with remote sensing detected vegetation phenology for improved modeling of ecohydrological processes

The Soil and Water Assessment Tool (SWAT) model has been widely applied for simulating the water cycle and quantifying the influence of climate change and anthropogenic activities on hydrological processes. A major uncertainty of SWAT stems from the poor representation of vegetation dynamics due to the use of a simplistic vegetation growth and development module. Using long-term remote sensing-bas

A global assessment of the species composition and effectiveness of watermelon pollinators and the management strategies to inform effective pollination service delivery

For most food crops the identity and efficiency of pollinators across key growing regions remains a significant knowledge gap that needs to be addressed before we can develop crop-specific approaches for pollination service delivery. Here, we conducted a systematic literature review and meta-analysis on watermelon (Citrullus lanatus (Thunb. Matsum. & Nakai)), a globally important fruit crop, t