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Vardagsliv - aktivitetsbalans och meningsfullhet i dagliga aktiviteter hos personer med psykiskt funktionshinder

Denna rapport vänder sig i huvudsak till arbetsterapeuter och arbetsstuderande som arbetar eller kommer att arbeta med personer med psykiskt funktionshinder och deras aktivitetsproblematik. I början av rapporten beskrivs kortfattat vad psykiskt funktionshinder innebär och vad det kan betyda för en person att leva med psykiskt funktionshinder, främst gällande aktiviteter i vardagen utifrån aktuell FSA anser att det ligger ett stort värde i att arbeten av väsentlig betydelse för arbetsterapins och arbetsterapeuters utveckling, presenteras på ett lätttillgängligt sätt. Mot denna bakgrund har förbundet beslutat att ge ut FoU-rapporter. I denna FoU-rapport delger författaren Christel Leufstadius (Leg. Arbetsterapeut, Dr. med.vet.) oss information om att leva med psykiskt funktionshinder samt te

Modeling the electrostatic charging of a helicopter during hovering in dusty atmosphere

A helicopter flying through an atmosphere containing particulates may accumulate high electrostatic charges which can challenge its operational safety. In this paper we elaborate and validate a triboelectric charging model to predict the electrification experienced by a helicopter while hovering in dusty air. We employed Large Eddy simulations to describe the turbulent structures inherent in the f

The immunopathogenesis of immune thrombocytopenia : T cells still take center-stage

PURPOSE OF REVIEW: Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder in which T and B cells recognize platelet antigens and initiate antiplatelet destructive mechanisms such as peripheral Fc receptor-mediated phagocytosis in the spleen or megakaryocyte destruction/inhibition within the bone marrow. The purpose of this review is to report on the ITP pathophysiology literature publish

Intravenous immunoglobulin prevents murine antibody-mediated acute lung injury at the level of neutrophil reactive oxygen species (ROS) production

Transfusion-related acute lung injury (TRALI) is a leading cause of transfusion-associated mortality that can occur with any type of transfusion and is thought to be primarily due to donor antibodies activating pulmonary neutrophils in recipients. Recently, a large prospective case controlled clinical study of cardiac surgery patients demonstrated that despite implementation of male donors, a high

Transfusion of antibody-opsonized red blood cells results in a shift in the immune response from the red blood cell to the antibody in a murine model

BACKGROUND: It is well known that infusion of immunoglobulin (Ig)G-coated cells results in an inhibited antigen-specific humoral immune response compared to the cells themselves, a phenomenon termed antibody-mediated immune suppression (AMIS). Although this AMIS effect has been well described with many different types of cells as well as vaccines and insoluble antigens, the mechanisms behind this

Platelets and innate immunity

Although platelets are best known as primary mediators of hemostasis, this function intimately associates them with inflammatory processes, and it has been increasingly recognized that platelets play an active role in both innate and adaptive immunity. For example, platelet adhesive interactions with leukocytes and endothelial cells via P-selectin can lead to several pro-inflammatory events, inclu

In situ pneumococcal vaccine production and delivery through a hybrid biological-biomaterial vector

The type and potency of an immune response provoked during vaccination will determine ultimate success in disease prevention. The basis for this response will be the design and implementation of antigen presentation to the immune system. Whereas direct antigen administration will elicit some form of immunological response, a more sophisticated approach would couple the antigen of interest to a vec

Impacts of wind energy development on bats : A global perspective

Wind energy continues to be one of the fastest growing renewable energy sources under development, and while representing a clean energy source, it is not environmentally neutral. Large numbers of bats are being killed at utility-scale wind energy facilities worldwide, raising concern about cumulative impacts of wind energy development on bat populations. We discuss our current state of knowledge