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Natural history of a visceral leishmaniasis outbreak in highland Ethiopia

In May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemken, Ethiopia, a highland region where only few cases had been reported before. We analyzed records of VL patients treated from May 25, 2005 to December 13, 2007 by the only VL treatment center in the area, maintained by Médecins Sans Frontières-Ethiopia, Operational Center Barcelona-Athens. The median age was 18

Climate vs. Human Impact : Quantitative and Qualitative Assessment of Streamflow Variation

This paper presents a novel framework comprising analytical, hydrological, and remote sensing techniques to separate the impacts of climate variation and regional human activities on streamflow changes in the Karkheh River basin (KRB) of western Iran. To investigate the type of streamflow changes, the recently developed DBEST algorithm was used to provide a better view of the underlying reasons. T

Multicentre Outcomes of Redo Fenestrated/Branched Endovascular Aneurysm Repair to Rescue Failed Fenestrated Endografts

ObjectiveTo report the outcomes of redo fenestrated and/or branched endovascular aortic repair (F/BEVAR in FEVAR) to rescue previous failed FEVAR.MethodsRetrospective review of all consecutive patients undergoing F/BEVAR in FEVAR at eight aortic centres including pre-, intra-, and post-operative data according to a pre-established protocol. Follow up consisted of at least yearly computed tomograph

Lack of knowledge regarding HPV and its relation to oropharyngeal cancer among medical students

Background: Oropharyngeal cancer (OPC) is an important cause of cancer-related mortality. Early detection of OPC results in a favorable prognosis and higher survival rates. Infection by high-risk types of human papillomavirus (HPV) is a risk factor for OPC with an upward trend globally. Medical students' knowledge and awareness of HPV-related OPC can be crucial in the preventive efforts. Aim: To a

Effect of PEGylation on Host Defense Peptide Complexation with Bacterial Lipopolysaccharide

Conjugation with poly(ethylene glycol) ("PEGylation") is a widely used approach for improving the therapeutic propensities of peptide and protein drugs through prolonging bloodstream circulation, reducing toxicity and immunogenicity, and improving proteolytic stability. In the present study, we investigate how PEGylation affects the interaction of host defense peptides (HDPs) with bacterial lipopo

Pesticide residues in fruits and vegetables from the southern part of Botswana

This study reports a surveillance of multi-pesticide residues of fruits and vegetables sold in the local markets carried out in 2018–2019 in Botswana to access consumer safety. A validated method for analysis of 232 pesticide residues in fruits and vegetables was applied, based on QuEChERS-GC-MS/MS methodology. A total of 83 fruit and vegetable sold in different markets were bought from three diff

DBT-skills system for cognitively challenged individuals with self-harm: a Swedish pilot study

Background: Dialectical behavior therapy (DBT) is an evidence-based treatment for self-harm and emotion regulation difficulties. A modified version, DBT-Skills System (DBT-SS), has been developed in the USA for individuals with cognitive difficulties. The present study is a pilot study, testing the DBT-SS in a Swedish context.Methods: Six participants were treated with individual therapy and group

Traveler Biosecurity Behavior during the COVID-19 Pandemic : Effects of Intervention, Resilience, and Sustainable Development Goals

Even prior to COVID-19, biosecurity was a significant issue for tourism, especially at national borders. Since personal nonpharmaceutical interventions can be effective for an individual’s health and psychological resilience during a pandemic, understanding tourists’ biosecurity behavior is essential given the broader relationship with traveling during COVID-19. However, existing research has not

Global bifurcation of solitary waves for the Whitham equation

The Whitham equation is a nonlocal shallow water-wave model which combines the quadratic nonlinearity of the KdV equation with the linear dispersion of the full water wave problem. Whitham conjectured the existence of a highest, cusped, traveling-wave solution, and his conjecture was recently verified in the periodic case by Ehrnström and Wahlén. In the present paper we prove it for solitary waves

Cross-national differences in consumer responses to savoury crackers containing blackcurrant pomace

Juice-pressing residues, among them blackcurrant pomace, are valuable materials for being upgraded in food products. Their excellent nutritional profiles in line with their functional properties allow a wide range of applications. The current study was performed to evaluate the overall liking of a pomace-enriched thin crispy-baked bread product in five European countries, and to obtain suggestions

Anxiety, compassion and pride. How emotions elicited by the government’s handling of Covid-19 influences health-promoting behavior

This article explores how emotions connected to the Government’s handling of the Covid-19 outbreak in Sweden relates to behaviors to stop the spread of the virus, and which emotions functions as mediators in this relationship. The Swedish approach to handling the outbreak greatly differed from how many other Western European countries handled the situation and thus makes an important case to study

Sperm DNA fragmentation index and cumulative live birth rate in a cohort of 2,713 couples undergoing assisted reproduction treatment

Objective: To study how the choice of the first assisted reproductive technology treatment type affects the cumulative live birth rate (CLBR) in couples with high sperm DNA fragmentation index (DFI). Design: Longitudinal cohort study. Setting: University-affiliated fertility clinic. Patient(s): A total of 2,713 infertile couples who underwent assisted reproductive technology treatment between 2007

e-Glass: A Wearable System for Real-Time Detection of Epileptic Seizures

Today, epilepsy is one of the most common chronic diseases affecting more than 65 million people worldwide and is ranked number four after migraine, Alzheimer's disease, and stroke. Despite the recent advances in anti-epileptic drugs, one-third of the epileptic patients continue to have seizures. More importantly, epilepsy-related causes of death account for 40% of mortality in high-risk patients.

Analysis of biased language in peer-reviewed scientific literature on genetically modified crops

Social, political, and economic forces may inadvertently influence the stance of scientific literature. Scientists strive for neutral language, but this may be challenging for controversial topics like genetically modified (GM) crops. We classified peer-reviewed journal articles and found that 40% had a positive or negative stance towards GM crops. Proportion of positive and negative stance varied

Microfluidic chips provide visual access to in situ soil ecology

Microbes govern most soil functions, but investigation of these processes at the scale of their cells has been difficult to accomplish. Here we incubate microfabricated, transparent ‘soil chips’ with soil, or bury them directly in the field. Both soil microbes and minerals enter the chips, which enables us to investigate diverse community interdependences, such as inter-kingdom and food-web intera

Open Data Ecosystems - an empirical investigation into an emerging industry collaboration concept

Software systems are increasingly depending on data, particularly with the rising use of machine learning, and developers are looking for new sources of data. Open Data Ecosystems (ODE) is an emerging concept for data sharing under public licenses in software ecosystems, similar to Open Source Software (OSS). It has certain similarities to Open Government Data (OGD), where public agencies share da