Dynamic chromatin structure is a fundamental property of gene transcriptional regulation, and has emerged as a critical modulator of physiological processes during cellular differentiation and development. Analysis of chromatin structure using molecular biology and biochemical assays in rare somatic stem and progenitor cells is key for understanding these processes but poses a great challenge beca

Central Asian countries are facing multidimensional political stability and security challenges in the post-Soviet period. Current scholarly discussions of political stability in post-Soviet Central Asia continue to revolve around the issues of Islamic upheaval, ethnic conflicts, civil war or inter-clan struggles, and how the authoritarian regimes in this region deploy coercive strategies and pena

Background and purpose Spasticity and muscle contracture are two common manifestations of cerebral palsy (CP). A spastic muscle may inhibit growth in length of the muscle, but the importance of this relationship is not known. In 1994, a register and a healthcare program for children with CP in southern Sweden were initiated. The child's muscle tone according to the Ashworth scale and the ankle ran

Swedish children’s use of the headshake from 18 to 30 months shows a developmental progression from rote-learned coordination with speech to increasingly more flexible and productive coordination with speech. To deal with these observations, I introduce the concept of multimodal constructions in order to extend usage-based approaches to language learning and construction grammar into the kinetic d

Review A coherent alternative to an economic approach of corporate governance is missing. In this paper we take steps towards developing a behavioral theory of boards and corporate governance. Building upon concepts such as political bargaining, routinization of decision making, satisficing, and problemistic search, a behavioral theory of boards and corporate governance will focus more on (1) inte

Recension av Lennart Leopold & Eva Ström (red.); Det var ingen tjusande idyll. Gustaf Hellström och hans tid.

Aims: To evaluate the predictive potential of preoperative psychological and psychophysiological variables in estimating severity of postoperative pain following mandibular third molar surgery (MTMS). Methods: Following ethical committee approval and informed consent, 40 consecutive patients scheduled for MTMS were included. Preoperative psychometric indicators of anxiety, depression, and vulnerab

We report the observation of anomalous bands in graphite valence band structure in angle-resolved photoemission spectroscopy (ARPES) experiments. The photon energy dependence of these bands shows a constant kinetic energy nature. Our results are supported by the very low energy electron diffraction data reported on graphite surfaces which essentially map the unoccupied states representing the phot

Background Patients with chromosome 5 abnormalities and high-risk myelodysplastic syndromes or acute myeloid leukemia have a poor outcome. We hypothesized that increasing doses of lenalidomide may benefit this group of patients by inhibiting the tumor clone, as assessed by fluorescence in situ hybridization for del(5q31). Design and Methods Twenty-eight patients at diagnosis or with relapsed disea

Differential absorption lidar (DIAL) techniques have been utilized to measure elemental gaseous mercury fluxes from mercury cell chlor-alkali (MCCA) plants as a part of the European Union funded European mercury emissions from chlor-alkali plants (EMECAP) project. Three plants have been selected as study objects and a total of six measurement campaigns have been performed, one intercalibration cam

PURPOSE: A Swedish and Norwegian study was designed to examine health-related quality of life (HQL) in patients with head and neck cancer (head and neck) at diagnosis and during treatment and rehabilitation. The overall aim was to examine the impact on HQL at diagnosis depending on tumor location, stage, sex, and age (part I) and to describe HQL longitudinally and determine for which patients and

Between May and December 1998, tick-associated febrile illness was prospectively studied in Southeast Sweden in order to assess the occurrence of human granulocytic ehrlichiosis (HGE). Inclusion criteria were fever (greater than or equal to 38.0degreesC), with or without headache, myalgia or arthralgia in patients with an observed tick bite or tick exposure within 1 month prior to onset of symptom

Direct photons are a powerful probe to study the property of quark–gluon plasma (QGP) in high energy heavy-ion collisions. In non-central collisions, the anisotropy of the collision region produces the different pressure gradients and particle density that results in different anisotropy of particle emission, depending on the production processes of photons. Therefore, an azimuthal anisotropy para

Three recent randomised trials have shown a lack of effect of EGDT for the treatment of severe sepsis and septic shock. Notably, control group care was excellent in all trials, including early recognition, early and aggressive fluid resuscitation and prompt administration of antibiotics, and was reflected in a lower than expected mortality.The discussion emphasizes the need for continued vigilanceThree recent randomised trials have shown a lack of effect of EGDT for the treatment of severe sepsis and septic shock. Notably, control group care was excellent in all trials, including early recognition, early and aggressive fluid resuscitation and prompt administration of antibiotics, and was reflected in a lower than expected mortality.The discussion emphasizes the need for continued vigilance

Patients with antineutrophil cytoplasm antibody-associated vasculitis (AAV) requiring dialysis at diagnosis are at risk for developing end-stage renal disease (ESRD) or dying. Shortterm results of a trial comparing plasma exchange (PLEX) to intravenous methylprednisolone (IV MeP) suggested PLEX improved renal recovery. Here we conducted long-term follow-up to see if this trend persisted. A total o

Popular Abstract in Undetermined I den här populärvetenskapliga sammanfattningen berörs avhandlingen Gradient Methods for Large-Scale and Distributed Linear Quadratic Control. Hur kan jetflygplan hålla sig i luften? Hur kan en Segway balansera en människa? Dessa frågor och många fler kan besvaras med hjälp av reglerteknik. Reglerteknik är ett område som behandlar hur man automatiskt styr system oThis thesis considers methods for synthesis of linear quadratic controllers for large-scale, interconnected systems. Conventional methods that solve the linear quadratic control problem are only applicable to systems with moderate size, due to the rapid increase in both computational time and memory requirements as the system size increases. The methods presented in this thesis show a much slower