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Characterization and evaluation of photolabile (µ-peroxo)(µ-hydroxo)bis[bis(bipyridyl)cobalt caged oxygen compounds to facilitate time-resolved crystallographic studies of cytochrome c oxidase

Photolabile (µ-peroxo)(µ-hydroxo)bis[bis(bipyridyl)-cobalt-based caged oxygen compounds have been synthesized and characterized by optical absorbance spectroscopy, X-ray crystallography. and the quantum yield and redox stability were investigated. Furthermore, conditions were established where redox incompatibilities encountered between caged oxygen compounds and oxygen-dependant cytochrome c oxid

Painting Taylor vortices with cellulose nanocrystals : Suspension flow supercritical spectral dynamics

We study the flow stability and spatiotemporal spectral dynamics of cellulose nanocrystal (CNC) suspensions in a custom Taylor-Couette flow cell using the intrinsic shear induced birefringence and liquid crystalline properties of CNC suspensions for flow visualizations, for the first time. The analysis is performed at constant ramped speed inputs of the independently rotating cylinders for several

Restrictive Spirometric Pattern and Preserved Ratio Impaired Spirometry in a Population Aged 50–64 Years

Rationale: Knowledge regarding the prevalence and shared and unique characteristics of the restrictive spirometric pattern (RSP) and preserved ratio impaired spirometry (PRISm) is lacking for a general population investigated with post-bronchodilator spirometry and computed tomography of the lungs. Objectives: To investigate shared and unique features for RSP and PRISm. Methods: In the Swedish CAr

A machine learning tool for identifying newly diagnosed heart failure in individuals with known diabetes in primary care

Aims: We aimed to create a predictive model utilizing machine learning (ML) to identify new cases of congestive heart failure (CHF) in individuals with diabetes in primary health care (PHC) through the analysis of diagnostic data. Methods: We used a sex- and age-matched case–control design. Cases of new CHF were identified across all outpatient care settings 2015–2022 (n = 9098). We included indiv

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STOP START PAUSE is a performance created by LIMINAL performance group in close collaboration with Danish artist duo Hesselholdt & Mejlvang.The audience was met by three emissaries armed with banners, symbols, fanfares and beliefs. They had come to help us to a new beginning without the conflicts and problems of our time. And asked the question: how do we free ourselves from ingrained patterns

"De kallade mig en bråkig unge tills jag blev en bråkig unge" - Beskrivningar av orsaker till kriminalitet och avhållsamhet i podcastavsnitt

The aim of this study was to understand, through interview-format podcasts, how individuals who have committed criminal acts from a young age described their pathway into crime and their process of desistance. Our study was based on a qualitative approach in the form of a thematic analysis of eight podcast episodes. We analyzed the empirical data using Howard S. Becker’s labeling theory (2006) and

Distribution of responsibility for AI development: Expert views

The purpose of this paper is to increase the understanding of how different types of experts with influence over the development of AI, in this role, reflect upon distribution of forward-looking responsibility for AI development with regard to safetyand democracy. Forward-looking responsibility refers to the obligation to see to it that a particular state of affairs materialise. In the context of

Pesticide Exposure and Effects on Non-Apis Bees

Bees are essential pollinators of many crops and wild plants, and pesticide exposure is one of the key environmental stressors affecting their health in anthropogenically modified landscapes. Until recently, almost all information on routes and impacts of pesticide exposure came from honey bees, at least partially because they were the only model species required for environmental risk assessments

Spectrum arguments, parity and persistency

This article shows that introducing the positive comparative relation parity only helps one block so-called “Spectrum Arguments” in order to avoid their unsavoury implications if one specifies parity in a specific way with respect to its persistence. The article illustrates how parity must both admit of persistency and be weakly non-persistent for parity to block Spectrum Arguments, and identifies

DOING SILENCE : HOW SILENCE IS PRODUCED IN MEETINGS

Authoritarian management and dysfunctional practices and processes have long been seen as the underlying systemic causes of silence within organizations. Individual responses to these causes, rooted in fear and futility, have been the accompanying explanations. While both types of factors contribute to a climate of silence, their dominance in certain contexts—such as consultative meetings among hi

A New IL-6-Inducing Mechanism in Cancer with New Therapeutic Possibilities

Background: Interleukin-6 is dysregulated in multiple pathological conditions, e.g., cancer and inflammatory diseases. Aim: To investigate new mechanisms for the regulation of pathological IL-6 production. Methods: PBMCs (peripheral blood mononuclear cells) stimulated by cancer serum factors or specific peptides produce interleukin-6 (IL-6). Immunoregulatory albumin neo-structures and peptides wer

Instantaneous thermometry imaging using two-photon laser-induced fluorescence

Measuring temperature in complex two-phase flows is crucial for understanding the dynamics of heat and mass transfer. In this Letter, we introduce a novel, to the best of our knowledge, optical approach based on the combination of two-photon laser-induced fluorescence (2p-LIF) imaging and two-color laser-induced fluorescence (2CLIF) for instantaneous temperature mapping of complex liquid media. Us

Increasing, not Diminishing : Investigating the Returns of Highly Maintainable Code

Understanding and effectively managing Technical Debt (TD) remains a vital challenge in software engineering. While many studies on code-level TD have been published, few illustrate the business impact of low-quality source code. In this study, we combine two publicly available datasets to study the association between code quality on the one hand, and defect count and implementation time on the o

Advanced Medium-Large Steam Cycles

Currently facing the problems of security of supply and higher electricity prices in southern Sweden, a medium-large power plant is considered to be built. To prepare for the possible outcome, a study of different cycle configurations was conducted. The study analyzed a 500 MWeldistrict heating mode power plant based on the Avedare power plant in Denmark, a single reheat Rankine cycle with a heat

Cluelessness and rational choice : The case of effective altruism

This present contribution presents an approach to making rational choices in face of cluelessness, focusing on effective altruism. I begin by illustrating how effective altruism faces the challenge of cluelessness, which implies a particular kind of incompleteness I call practical incompleteness. I then argue that this is not a reason for proponents of effective altruists to become skeptics, but r

Is there a “divine” definition of riba and its scope in the Holy Quran?

Getting or paying “interest” on loans is probably the most vehemently and frequently debated subject of Islamic economics. There is no doubt that the Holy Quran forbids riba, but the question is: Does the Holy Quran give a “divine” definition of riba or its scope? Unfortunately, the Holy Book of Islam, which is the primary source of reference for Muslims, offers no “divine” definitions. Definition

First case of mpox with monkeypox virus clade Ib outside Africa in a returning traveller, Sweden, August 2024 : public health measures

An unprecedented upsurge in mpox, caused by clade I of the monkeypox virus (MPXV) was noted in Central Africa in 2024. The first mpox case with MPXV clade Ib outside Africa was reported in Sweden in mid-August. The case experienced a mild disease course after travelling to an affected country. No additional cases of this clade have been detected in Sweden. Strengthened public health measures and s