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Tacrine treatment modifies cerebrospinal fluid neuropeptide levels in Alzheimer's disease

Biochemical and histochemical studies have demonstrated a widespread deficit in the activity of acetylcholinesterase (AChE) in the brains of patients with Alzheimer's disease (DAT). Multiple disturbances in several transmitter systems have been found. The most consistent neurochemical changes in DAT are reductions in the cholinergic system. The major pharmacological approach today in DAT is based

ABS control - A design model and control structure

The Anti-lock Braking System is an important component of acomplex steering system for the modern car. Most of ABS controllersavailable on the market are table and relay-feedback based.In the latest generation of “brake by wire” systems, the performancerequirements on the ABS are much higher. Control objective shiftsto maintain a specified tire slip during braking. The authors propose a design mod

Imperatives in bilingual child Icelandic-English

The syntax of imperatives makes an interesting test case when investigating word order, verb raising and cliticisation across languages and their acquisition. This paper looks at language differentiation, i.e. language-specific parameter setting, in the imperative constructions of a bilingual child, "Katla", acquiring a verb-raising language, Icelandic, as well as English, not a verb-raising langu

Microorganisms in the Indoor Environment Analysis and Structure-Bioactivity Relationships

Popular Abstract in Swedish Otillfredsställande inandningsluft på bl a arbetsplatser har satts i samband med utveckling av olika akuta och kroniska symptom såsom allergi, astma och kronisk bronkit. Vi vet att bakterier och svamp producerar ett stort antal ämnen som verkar irriterande eller är allergiframkallande. Misstankar har därför riktas mot olika mikrobiologiska ämnen i luften såsom endotoxinInhalation of air-borne microorganisms and components thereof can cause illnesses and diseases. However, lack of specific and sensitive methods for exposure assessment can pose problems in predicting health outcomes. Characterization of microbial load from indoor environments using gas chromatography-mass spectrometry (GC-MS) and/or tandem mass spectrometry (GC-MSMS) as well as various bioassays (