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Shifting sands : Legal dispossession of small-scale miners in an extractivist era

This article argues that the entanglements of a growing global demand for construction material and neoliberal resource governance result in an incremental and piecemeal form of dispossession. While mining in Colombia has been broadly researched, little has been said about sand extraction and the challenges small-scale artisanal miners face when trying to formalise their activities. This article s

Flow and thermal performance of supercritical n-decane in double-layer channels for regenerative cooling of a scramjet combustor

In order to improve the active regenerative cooling performance of a scramjet using supercritical n-decane, a new type of cooling channel, the double-layer channel, is proposed. Based on reliable numerical simulations, temperature profiles, fluid flow track, vortex structure and buoyancy force distribution of three cases are presented, respectively. It is found that the heat transfer performance o

ECG-Derived Respiratory Rate in Atrial Fibrillation

Objective: The present study addresses the problem of estimating the respiratory rate from the mor- phological ECG variations in the presence of atrial fibrilla- tory waves (f-waves). The significance of performing f-wave suppression before respiratory rate estimation is investi- gated. Methods: The performance of a novel approach to ECG-derived respiration, named “slope range” (SR) and de- signed

Did Industrialization Lead to Segregation in Cities of the Nineteenth Century? The Case of Uppsala 1880–1900

How did industrialisation affect land use and residential patterns in cities of the nineteenth century? We use census data and GIS mapping techniques to analyse class segregation and changes to the spatial structure using the case of Uppsala, Sweden between 1880 and 1900. We find that there was a clear concentration of business activity in the central district and in proximity to the transportatio

Chronic nodular prurigo : clinical profile and burden. A European cross-sectional study

Background: Chronic nodular prurigo (CNPG) is a condition characterized by chronic itch, a prolonged scratching behaviour and the presence of pruriginous nodules. A comprehensive understanding of this condition, especially regarding its clinical characteristics and impact on quality of life is still lacking. Objectives: Aim of this pan-European multicentre cross-sectional study was to establish th

Autologous haematopoietic stem-cell transplantation versus bortezomib–melphalan–prednisone, with or without bortezomib–lenalidomide–dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study

Background: The emergence of highly active novel agents has led some to question the role of autologous haematopoietic stem-cell transplantation (HSCT) and subsequent consolidation therapy in newly diagnosed multiple myeloma. We therefore compared autologous HSCT with bortezomib–melphalan–prednisone (VMP) as intensification therapy, and bortezomib–lenalidomide–dexamethasone (VRD) consolidation the

Enhancement of α-particle formation near 100Sn

The superfluid tunneling model is applied to the calculation of ground-state–to–ground-state α decay in the even-even neutron-deficient Te-Ba nuclei. We show that there is a larger α-particle formation probability in nuclei of this region above 100Sn when compared to analogous nuclei above 208Pb. This is consistent with the expected systematic variation of the pair gap Δ as a function of mass numb

Fetal exposure to paternal smoking and semen quality in the adult son

Background: The negative impact of maternal smoking during pregnancy on offspring semen quality is well established. Less is known about the impact of paternal smoking. Methods: We estimated differences in semen parameters and testicle size according to paternal smoking in 772 adult sons of women enrolled in the Danish National Birth Cohort when pregnant. Parents’ smoking was reported around gesta

Surface-modified nanoerythrosomes for potential optical imaging diagnostics

Nanoerythrosomes (NERs), vesicle-like nanoparticles derived from red blood cells, represent a new and interesting vector for therapeutic molecules and imaging probes, mainly thanks to their high stability and excellent biocompatibility. Aiming to present a proof-of-concept of the use of NERs as diagnostic tools for in vitro/in vivo imaging purposes, we report here several functionalization routes

The coordinated outcome of STIM1-Orai1 and superoxide signalling is crucial for headkidney macrophage apoptosis and clearance of Mycobacterium fortuitum

The mechanisms underlying M. fortuitum-induced pathogenesis remains elusive. Using headkidney macrophages (HKM) from Clarias gariepinus, we report that TLR-2-mediated internalization of M. fortuitum is imperative to the induction of pathogenic effects. Inhibiting TLR-2 signalling alleviated HKM apoptosis, thereby favouring bacterial survival. Additionally, TLR-2-mediated cytosolic calcium (Ca2+)c

Critical longitudinal ventilation velocity for smoke control in a tunnel induced by two nearby fires of various distances : Experiments and a revisited model

Fire smoke in a tunnel fire is a key factor causing casualties, thus the critical longitudinal ventilation velocity is a key parameter in tunnel fire safety ventilation design. The correlation of critical longitudinal ventilation velocity for smoke control in a tunnel induced by two nearby fires has rarely been studied experimentally and quantified before, despite the fact that this scenario exist

CONCEPTUAL DESIGN FOR ADDITIVE MANUFACTURING: AN EXPLORATIVE STUDY

With the broader industrial application of Additive Manufacturing (AM), designers are facing new challenges in conceptual design for AM. To better understand the problematic, the authors organised a design workshop with six experts in AM. The paper presents the results of the conducted design workshop and discusses the current and future trends in research on the conceptual design for AM.

Attosecond timing of electron emission from a molecular shape resonance

Shape resonances in physics and chemistry arise from the spatial confinement of a particle by a potential barrier. In molecular photoionization, these barriers prevent the electron from escaping instantaneously, so that nuclei may move and modify the potential, thereby affecting the ionization process. By using an attosecond two-color interferometric approach in combination with high spectral reso

Diverging responses to threats across generations in zooplankton

Our understanding on how organisms evolutionarily cope with simultaneously occurring, multiple threats over generations is still elusive. In a long-term experimental study, we therefore exposed clones of a freshwater cladoceran, Daphnia magna, to threats from predation and ultraviolet radiation (UVR) during three consecutive parthenogenetic generations. We show that Daphnia can adapt to different

Imaging strain localisation in porous andesite using digital volume correlation

Strain localisation structures, such as shear fractures and compaction bands, are of importance due to their influence on permeability and therefore outgassing, a factor thought to influence eruptive style. In this study, we aim to develop a better understanding of strain localisation in porous volcanic rocks using X-ray tomographic images of samples of porous andesite (porosity = 0.26) acquired b