Popular Abstract in Swedish Brosk är en speciell typ av vävnad, som bl.a. finns på våra ledytor, där det fungerar som ett stötdämpande och skyddande lager för benet. Broskets viktiga egenskaper framstår klart vid sjukdomar, som artros, där brosket på ledytor har förstörts och benet blottläggs, vilket resulterar i en permanent smärta. Brosk produceras av den enda celltyp som finns i broskvävnaden; The aim of this thesis was to study the function of the integrin a10b1. Integrins mediate signals between cells and their environment and regulate several cellular processes such as cell migration, proliferation and differentiation. The a10b1 integrin is expressed mainly by chondrocytes, the only cell type present in cartilage, and facilitates binding of the chondrocytes to the extracellular matri

Multi-step ahead response time prediction of CPU constrained computing systems is vital for admission control, overload protection and optimization of resource allocation in these systems. CPU constrained computing systems such as web servers can be modeled as single server queuing systems. These systems are stochastic and nonlinear. Thus, a well-designed nonlinear prediction scheme would be able

Eukaryotic protein kinases, containing a conserved catalytic domain, represent one of the largest superfamilies of the eukaryotic proteins and play distinct roles in cell signaling and diseases. Near completion of rat genome sequencing project enables the evaluation of a near complete set of rat protein kinases. Publicly accessible genetic sequence databases were searched for rat protein kinases,

Bildens roll i vetenskapen har skiftat med synen på vad vetenskap är. Det fanns en tid då bara det konstnärliga geniet ansågs kapabel att fånga sanningen i bild. Mot slutet av 1700-talet var det i stället sparsmakade grafiska illustrationerna som gällde; estetik ansågs leda till subjektiv förvillelse och blockera vetenskaplig kunskap. Med dagens digitala bildteknik har den vetenskapliga illustrati

In a context of complex problem spaces, human individuals need support to carry out in-depth inquiry, generating many, diverse possibilities, without suffering from information overload. In earlier work, we have demonstrated the potential of a model of four-valued logic to provide support in a knowledge sharing environment by codifying, not knowledge, but categories of argument/assertion. In this

Near-IR light penetrates deeply into tissue, but as the scattering coefficient is much larger than the absorption coefficient in this wavelength region, direct viewing through tissue is very difficult. In order to detect and locate inhomogeneities located inside tissue a time-resolved technique was developed, based on gated viewing, i.e. detecting the first arriving photons with the shortest path

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We present an application of Sparse Bayesian Learning to the task of semantic role labeling, and we demonstrate that this method produces smaller classifiers than the popular Support Vector approach. We describe the classification strategy and the features used by the classifier. In particular, the contribution of six parse tree path features is investigated.

Abstract is not available