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Optimising conditions and environments for digital participation in later life: a macro-meso-micro framework of partnership-building

The ongoing digitalisation of societies, exacerbated by the COVID-19 pandemic, has led to increased efforts to ensure the digital inclusion of older adults. Digital inclusion strategies throughout the COVID-19 pandemic predominantly focused on increasing access and basic digital literacy of Information and Communication Technologies (ICTs) for all members of society. Older adults, who are more lik

Promoting healthy ageing in the Western Pacific: a mini review of good practices and policy responses

The Western Pacific Region is experiencing rapid population ageing, which has implications for almost all areas of society. Countries will need to prepare for population ageing by investing in health and optimizing living environments. This requires a whole-of-society approach to healthy ageing. Countries in the Western Pacific Region have been making significant progress in healthy ageing. Since

Meningioma microstructure assessed by diffusion MRI : An investigation of the source of mean diffusivity and fractional anisotropy by quantitative histology

BACKGROUND: Mean diffusivity (MD) and fractional anisotropy (FA) from diffusion MRI (dMRI) have been associated with cell density and tissue anisotropy across tumors, but it is unknown whether these associations persist at the microscopic level.PURPOSE: To quantify the degree to which cell density and anisotropy, as determined from histology, account for the intra-tumor variability of MD and FA in

Other syndromes of orthostatic intolerance : Delayed orthostatic hypotension, postprandial hypotension, postural orthostatic tachycardia syndrome, and reflex syncope

Apart from classical orthostatic hypotension, the gravitational force may strongly contribute to other forms of orthostatic intolerance, delayed and postprandial OH, postural orthostatic tachycardia syndrome (POTS), and reflex syncope. In delayed OH, the significant blood pressure drop occurs first after 3-min period of orthostasis, whereas in postprandial OH, the symptoms appear first approximate

New Targeted Interest Deduction Limitation Rules Post Lexel

Both the European Union (EU) Directive implementing the OECD’s Pillar Two and the proposal for a debt-equity bias reduction allowance (DEBRA) feature rules that target and limit interest deduction as the need for these still exists. However, in case C-484/19 Lexel from 2021, the Court of Justice of the European Union (CJEU) struck down the Swedish targeted interest deduction legislation of 2013 ap

Assessing the decennial, reassessing the global : Understanding European Union normative power in global politics

This concluding article assesses the past decade of international scholarship on the European Union (EU) and normative power as represented by the contributions to the special issue. It argues that the normative power approach (NPA) makes it possible to explain, understand and judge the EU in global politics by rethinking the nature of power and actorness in a globalizing, multilateralizing and mu

The 2012 Danish Presidency of the Council of the European Union : bridging exclusion

"You're an out, a small out, and you're new. We don't want to hear from you."(Nicolas Sarkozy, in Barker and Parker, 2011)Holding the rotating Presidency of the Council of Ministers of the European Union (EU) is a challenging task for any Member State, but in the context of the global financial and eurozone crisis, the perceived decline of EU influence in the world and the growing resentment of EU

Exploring total economic values in an emerging urban circular wastewater system

Circular water management has the potential to close resource and material loops within and across value chains. In the water industry, circular municipal wastewater management through industrial urban symbiosis (IUS) is recognized as a solution to overcome water scarcity in urban environments. IUS involves collaboration between actors with different organizational backgrounds, which can lead to i

MafB-dependent neurotransmitter signaling promotes β cell migration in the developing pancreas

Hormone secretion from pancreatic islets is essential for glucose homeostasis and loss or dysfunction of islet cells is a hallmark of type 2 diabetes. Maf transcription factors are critical for establishing and maintaining adult endocrine cell function. However, during pancreas development, MafB is not only expressed in insulin- and glucagon-producing cells, but also Neurog3+ endocrine progenitor

Antibiotic prophylaxis and its effect on postprocedural adverse events in endoscopic retrograde cholangiopancreatography for primary sclerosing cholangitis

BACKGROUND AND AIM: Primary sclerosing cholangitis (PSC) is characterized by multiple strictures of the biliary tree. Patients with PSC frequently require repeated endoscopic retrograde cholangiopancreatography (ERCP) procedures. These procedures are encumbered by an increased incidence of infectious adverse events such as cholangitis. Evidence regarding whether antibiotic prophylaxis (AP) should

Improved chemical recyclability of 2,5-furandicarboxylate polyesters enabled by acid-sensitive spirocyclic ketal units

Incorporating hydrolytically sensitive functional groups into polymer backbones provides a feasible strategy to trigger their degradation to the starting monomers, thus enabling chemical recycling of the material. Here, we present two series of copolyesters in which a biobased spirocyclic ketal-functional diester monomer was incorporated into poly(butylene 2,5-furandicarboxylate) (PBLF) and poly(h