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Dietary amino acids and risk of stroke subtypes : a prospective analysis of 356,000 participants in seven European countries

Purpose: Previously reported associations of protein-rich foods with stroke subtypes have prompted interest in the assessment of individual amino acids. We examined the associations of dietary amino acids with risks of ischaemic and haemorrhagic stroke in the EPIC study. Methods: We analysed data from 356,142 participants from seven European countries. Dietary intakes of 19 individual amino acids

Pharmacological and mechanical properties of isolated pig coronary veins

Recent successful cardiac transplantation from pig to non-human primates and the first pig-to-human transplantation has put the focus on the properties of the pig heart. In contrast to the coronary arteries, the coronary veins are less well characterized and the aim was to examine the mechanical and pharmacological properties of coronary veins in comparison to the arteries. Vessel segments from th

General dental practitioners' fees for root canal treatment, coronal restoration and follow-on treatment in the adult population in Sweden : A 10-year follow-up of data from the Swedish Dental Register

Objectives: To analyze the accumulated fees connected with root filling, permanent coronal restoration and follow-on treatment charged by Swedish dentists over a 10–11-year follow-up period. Furthermore, analyzing these fees with reference to the type of restoration, tooth group, and the root-filled teeth which survived compared to those requiring extraction. Material and Methods: In 2009, the dat

A mm-Wave Differential-to-Quadrature Frequency Tripler with Automatic Locking and Quadrature Correction

This paper presents an injection-locked frequency tripler for 28-GHz direct-conversion transceivers, which takes a differential input and outputs a quadrature signal. A feedback system is added to ensure that lock occurs and to keep the quadrature error below 1° across operating frequencies and process corners. Simulations show that the tripler can cover the entire 24-30 GHz band across all corner

Red cell distribution width and its polygenic score in relation to mortality and cardiometabolic outcomes

Introduction: Elevated red cell distribution width (RDW) has been associated with a range of health outcomes. This study aims to examine prognostic and etiological roles of RDW levels, both phenotypic and genetic predisposition, in predicting cardiovascular outcomes, diabetes, chronic kidney disease (CKD) and mortality. Methods: We studied 27,141 middle-aged adults from the Malmö Diet and Cancer s

Light elements Na and Al in 58 bulge spheroid stars from APOGEE

We identified a sample of 58 candidate stars with metallicity [Fe/H]-0.8 that likely belong to the old bulge spheroid stellar population, and analyse their Na and Al abundances from Apache Point Observatory Galactic Evolution Experiment (APOGEE) spectra. In a previous work, we inspected APOGEE-Stellar Parameter and Chemical Abundance Pipeline abundances of C, N, O, Mg, Al, Ca, Si, and Ce in this s

Association between low selenoprotein P concentrations and anaemia in hospitalized heart failure patients

AIMS: Heart failure (HF) patients with anaemia tend to have a worse outcome, with increased hospitalization rates, decreased exercise tolerance, and higher mortality compared to those without anaemia. Limited research exists on the association between selenium deficiency and anaemia specifically in HF patients, despite previous findings of a correlation in different populations. The BIOSTAT-CHF st

Investigating the amplitude and rotation of the phase spiral in the Milky Way outer disc

Context. With data releases from the astrometric space mission Gaia, exploration of the structure of the Milky Way is now possible in unprecedented detail, and has unveiled many previously unknown structures in the Galactic disc and halo. One such feature is the Gaia phase spiral where the stars in the Galactic disc form a spiral density pattern in the Z- VZ plane. Many questions regarding the pha

Electron population dynamics in resonant non-linear x-ray absorption in nickel at a free-electron laser

Free-electron lasers provide bright, ultrashort, and monochromatic x-ray pulses, enabling novel spectroscopic measurements not only with femtosecond temporal resolution: The high fluence of their x-ray pulses can also easily enter the regime of the non-linear x-ray-matter interaction. Entering this regime necessitates a rigorous analysis and reliable prediction of the relevant non-linear processes

Abdominal compression as motion management for stereotactic radiotherapy of ventricular tachycardia

Background and purpose: Stereotactic body radiotherapy (SBRT) has emerged as a promising treatment for patients with ventricular tachycardia (VT) who do not respond to standard treatments. However, the management of respiratory motion during treatment remains a challenge. This study aimed to investigate the effect of abdominal compression (AC) on respiratory induced motion in the heart. Materials

On the thermal conductivity anisotropy in wurtzite GaN

GaN-based power devices operating at high currents and high voltages are critically affected by the dissipation of Joule heat generated in the active regions. Consequently, knowledge of GaN thermal conductivity is crucial for effective thermal management, needed to ensure optimal device performance and reliability. Here, we present a study on the thermal conductivity of bulk GaN in crystallographi

On the role of internationalization of firm-level corporate governance : The case of audit committees

Research Question/Issue: Motivated by the agency theory and the findings of linguistic studies, we analyze the association between the internationalization of a firm's audit committee and its corporate governance. Research Findings/Insights: Based on data from 2159 publicly traded European firms from 15 countries for the period 2000–2018, we find that firms with foreign directors on their audit co

ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1

Background: 4-1BB (CD137) is a co-stimulatory receptor highly expressed on tumor reactive effector T cells and NK cells, which upon stimulation prolongs persistence of tumor reactive effector T and NK cells within the tumor and induces long-lived memory T cells. 4-1BB agonistic antibodies have been shown to induce strong anti-tumor effects that synergize with immune checkpoint inhibitors. The firs