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Peptidbaserade läkemedel utgör en växande del av läkemedelsindustrin, med behandlingsmöjligheter mot en bredd av sjukdomar. Det första peptidbaserade läkemedlet var insulin som introducerades under 1920-talet, sedan dess har applikationer av peptidläkemedel ökat, och tillverkningsmetoder utvecklats. Under 1960-talet introducerades fastfaspeptidsyntes (solid phase peptide synthesis, SPPS), där peptMethods for synthesis of peptides using solid phase peptide synthesis (SPPS) are hampered by relying on large amounts of hazardous substances such as dimethylformamide (DMF) as solvent for peptide assembly and trifluoroacetic acid (TFA) a per/polyfluoroalkyl substance (PFAS) as reagent/solvent for side chain protecting group (PG) removal and peptide resin cleavage. Advances have been made towards

In modern ASIC verification, bridging the gap between IP-level and system-level test environments is a major challenge, especially as system-on-chip (SoC) complexity grows. This thesis presents a novel methodology leveraging the Accellera Portable Stimulus Standard to enable portable, reusable verification scenarios across these levels. The approach introduces a pre-runtime signal forcing mechanis

I detta examensarbete undersöks det hur modeintresserade unga kvinnor i åldrarna 20-29 år utformar sina köp- och försäljningspraktiker av kläder på digitala secondhand-plattformar under en ekonomisk kris. Uppsatsen syftar till att utveckla befintlig forskning genom att skapa förståelse för unga kvinnors secondhand-praktiker under en ekonomiskt osäker tid. Studien utgår från en kvalitativ metod och

Abstract Title: Making Non-Financial Information Auditable: AI’s Influence on the Operationalization of Non-Financial Materiality Course: BUSN79 Degree Project: Accounting and Finance Course: BUSN79 Degree Project: Accounting and Finance Authors: Firangiz Heydarova and Mateusz Jocz Supervisor: Liesel Klemcke Examiner: Anders Anell Purpose: The study aims to explore how AI technologies influence th

How are brand characters portrayed in Formula 1 teams? The purpose of this study is to understand and describe brands and their brand characters within the experience market of Formula 1. We aim to contribute with conclusions regarding brand characters and their differentiation within the field of research of experience markets. The study adopts a qualitative and abductive approach, grounded in in

Undersökningen syftar till att öka förståelsen för hur yrkesidentitet uttrycks och formas i ett framväxande yrke, samt vilka organisatoriska villkor som påverkar yrkesidentitetens utveckling. Studien bygger på en kvalitativ fallstudie av det framväxande yrket trafikstyrning, ett yrke som präglas av låg synlighet, inom en svensk lagerverksamhet. Genom tolv semistrukturerade intervjuer analyseras hu

Certain organic micropollutants and emerging contaminants are increasingly detected in wastewater effluents due to enhancement of detection techniques and new technological processes or household items being introduced. Some of them can accumulate in food chains and/or pose health risks for humans, wildlife and ecosystems. Often, these are very difficult or impossible to sufficiently remove using

Denna rapport handlar om processen för att ge en robotarm möjligheten att läsa och utföra rörelser från en G-kodfil. En sådan lösning kan ha betydande fördelar för robotarmarnas ägare och tillverkare, genom att möjliggöra nya arbetsuppgifter. Vårt mål var att implementera en konceptuell demonstration som visar att robotarmen kan programmeras för att läsa G-kod och utföra uppgifter liknande de som This paper is about the process of making a general purpose robot arm able to read and execute movements from a G-code file. A solution to this problem could prove beneficial to the owners and developers of the robot as it could create new possible work tasks for said robot. Our goal is to implement a proof of concept that shows that the robot could be made to read g-code and do tasks that a 3D-pr

This thesis analyzes the novels Bränn alla mina brev and Jävla Karlar with focus on expressions of masculinities. The method is reparative reading which entails reading from a position of hope. The theoretical framework is primarily based on Connell’s masculinity theories, which are the hegemonic, complicit, subordinated, and marginalized masculinity. Complementary are Anderson’s theory of inclusi

I det svenska samhället syns en nedåtgående trend när det gäller barn och ungas läs- och skrivförmåga. Därmed finns det ett värde i att utforska effekter av läsfrämjande initiativ. Den aktuella studien ämnar således att studera vilken betydelse miljön på kulturhuset Funnys Äventyr kan ha i relation till högläsning. Mer specifikt undersöks vilken betydelse miljön har för barns nivå av distraktion o

Föreliggande uppsats undersöker hur tystnad gestaltas i Maja Lee Langvads Tolk (2024). Genom att gå i dialog med Mara Lees avhandling i litterär gestaltning När Andra skriver: skrivande som motstånd, ansvar och tid (2014) belyses hur tystnaden i Lee Langvads roman kan förstås som något rumsligt, relationellt och tidsligt. Från Lees avhandling hämtas begrepp som Andra, temporalitet och förskjutning

Purpose: The purpose of this thesis has been to examine if and how Swedish SMEs use post audit reviews to learn from their capital investment decisions. Methodology: This explorative study applies a qualitative research approach, using both primary and secondary data. The primary data was collected through semi structured interviews with six managers across six different Swedish SMEs, while secon

This thesis examines how insights from cognitive science can inform the design of self-study training materials to reduce cognitive load and enhance sales onboarding in complex technical domains. The study was conducted at a global company specializing in industrial sensor solutions, focusing on machine vision sales training. The study was conducted in three phases. First, a pre-study mapped the

In today’s technology-driven classrooms, maintaining student focus is increasingly challenging. This study investigates the impact of "Focus room", a digital tool developed by Trelson, designed to reduce digital distractions and support sustained attention during class. Through an observational study in a Swedish school, four 8th grade student classes were observed before and during the

Europe has undergone major changes since the beginning of the cold war and the last decade has proven to be a very challenging chapter. To reach a consensus, EU’s member states would have to cooperate, but the tools to achieve this were absent. With the introduction of the Treaty of Amsterdam the member states had to submit to the ruling of the European Parliament. The result was significantly str

Föreställ dig att du bor i ett bostadsområde men tvingas flytta på grund av höjda boendekostnader till följd av stadsförnyelse, som utlovar högre kvalitet i form av ett levande torg och nya gröna parker. Ditt bostadsområde har genomgått en gentrifieringsprocess – något som kan uppstå som en konsekvens av stadsförnyelse. Göteborg är en stad som likt många andra brottas med segregation och samtidiSocial and climate-related challenges are closely intertwined. Existing research has shown that community’s ability to recover from extreme weather events is largely influenced by social vulnerabilities and societal resilience. In response, environmental justice has emerged as a potential tool to address these dual challenges in urban planning. Within this context, strategies such as urban densifi

This thesis examines whether ideological shifts in Swedish municipal councils affect local taxation and spending. Using close elections from 1998 to 2018 and a left-right index based on party seat shares and economic positions, it applies a multi-score regression discontinuity design with instrumental variables. The study finds that while tax rates and core welfare spending are unaffected, a right

Climate change and socio-economic developments are projected to intensify land use pressures in northern latitudes, potentially driving agricultural expansion into Arctic and boreal ecosystems. This thesis examines the consequences of future climate and land use change on ecosystem services in the European Arctic, focusing on vegetation dynamics, carbon storage, crop productivity, and biophysical