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Bisphosphonates for orthopedic applications. Studies in rat models

Popular Abstract in Swedish Denna avhandling undersöker förutsättningarna för att stoppa nedbrytning av benvävnad med hjälp av bifosfonater i några ortopediska problemsituationer. Bifosfonater är en relativt ny grupp av läkemedel som hämmar nedbrytning av benvävnad. De binder effektivt till benmineral och i praktiken förblir de inbundna i skelettet tills benmineralet upplöses. Bifosfonater finns iProsthetic loosening, bone graft resorption and osteonecrosis are examples of problems in orthopedic surgery caused by or augmented by bone resorption. Bone resorption is caused by osteoclasts. Osteoclasts can be inactivated with biphosphonates, a drug in clinical use against osteoporosis and osteolytic tumors. The bone resorption-reducing ability of bisphosphonates was analyzed in rat models. An

Motion Estimation in Image Sequences Using the Deformation of Apparent Contours

The problem of determining the camera motion from apparent contours or silhouettes of curved three-dimensional surfaces is considered. In a sequence of images is shown how to use the generalized epipolar constraint on apparent contours. One such constraint is obtained for each epipolar tangency point in each image pair. Thus in theory the motion can be calculated from the deformation of a single c

“Outside” directors in SME boards: a call for theoretical reflections

Good governance for SMEs is critical for economic development and growth in both developed and developing economies. In this paper we focus on boards and governance in small and medium sized enterprises (SMEs) by investigating the role and contribution of “outside” directors in this setting. By contrasting board role theories against different types of SMEs, firms are expected to recruit “outside”

Propaganda som vapen

Text om propaganda i olika medier, från 1500-talet fram till våra dagar. Särskild uppmärksamhet ägnas legitimitetsaspekter och trovärdighetsfrågor i olika slags propaganda.