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Ambient pressure x-ray photoelectron spectroscopy study on the initial atomic layer deposition process of platinum

The initial adsorption of MeCpPtMe 3 is investigated using synchrotron-based ambient pressure x-ray photoelectron spectroscopy (XPS). The experiments are done on a native oxide-covered Si substrate. In addition, a reaction with O 2 and the created Pt surface was investigated. Inspiration for the reaction studies was found from atomic layer deposition of metallic Pt, process that uses the same comp

Time-resolved ambient pressure x-ray photoelectron spectroscopy : Advancing the operando study of ALD chemistry

Today, atomic layer deposition (ALD) has become a firm corner stone of thin film deposition technology. The microelectronics industry, an early adopter of ALD, imposes stringent requirements on ALD to produce films with highly defined physical and chemical properties, which becomes even more important as device and component dimensions decrease. This, in turn, means that our understanding of the c

Evaluation of the 2023 Duke-ISCVID criteria for infective endocarditis in patients referred to the Lund infective endocarditis team

Background: The Duke criteria for diagnosing infective endocarditis (IE) were recently updated by the International Society for Cardiovascular Infectious Diseases (ISCVID) with the purpose of enhancing diagnostic specificity and sensitivity. This study investigated the performance of the Duke-ISCVID criteria in relation to previous criteria. Method: This retrospective single centre cohort study in

Apixaban vs rivaroxaban in patients with atrial fibrillation at high or low bleeding risk : A population-based cohort study

Background: Despite many atrial fibrillation (AF) patients being at risk of bleeding, very limited data are available on bleeding rates of different direct oral anticoagulants based on the spectrum of bleeding risk. Objective: We aimed to compare the risk of major bleeding and thromboembolic events with apixaban vs rivaroxaban for AF patients stratified by bleeding risk. Methods: We conducted a po

Prevalence of sexually transmitted infections and associated risk factors among female sex workers in Guinea-Bissau

Objective To estimate the prevalence of the curable sexually transmitted infections (STIs) Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis and Treponema pallidum, to identify associated risk factors and to assess ciprofloxacin resistance in N. gonorrhoeae-positive specimens among female sex workers (FSWs) in Guinea-Bissau. Methods For this cross-sectional

Setting New Standards: EU Regulation meets Digitalisation

In this article, we present our edited volume, "New Directions in Digitalisation: Perspectives from EU Competition Law and the Charter of Fundamental Rights." We examine the EU's recent regulatory initiatives, particularly the Digital Markets Act (DMA), and their implications for competition law and fundamental rights. The article provides an analysis of how the DMA aims to address market imbalanc

Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality

Genotypes causing pregnancy loss and perinatal mortality are depleted among living individuals and are therefore difficult to find. To explore genetic causes of recessive lethality, we searched for sequence variants with deficit of homozygosity among 1.52 million individuals from six European populations. In this study, we identified 25 genes harboring protein-altering sequence variants with a str

Review of 2022 PSOGI/RENAPE Consensus on HIPEC

The 2022 PSOGI (Peritoneal Surface Oncology Group International) and RENAPE (French Network for Rare Peritoneal Malignancies) consensus on hyperthermic intraperitoneal chemotherapy (HIPEC) was a comprehensive effort aimed at standardizing treatment protocols for various peritoneal malignancies. This initiative is critical due to the wide range of technical variations in HIPEC procedures and the re

Functional Optimization of Broadly Neutralizing HIV-1 Antibody 10E8 by Promotion of Membrane Interactions

The 10E8 antibody targets a helical epitope in the membrane-proximal external region (MPER) and transmembrane domain (TMD) of the envelope glycoprotein (Env) subunit gp41 and is among the broadest known neutralizing antibodies against HIV-1. Accordingly, this antibody and its mechanism of action valuably inform the design of effective vaccines and immunotherapies. 10E8 exhibits unusual adaptations

Novel methods to study amyloid oligomers

Amyloid protein deposits are the hallmark of neurodegenerative diseases such as Alzheimer’s, Parkinson’s, or diabetes type II. Although their connection to the diseases is not fully understood, many studies point at intermediate species called oligomers as being the main responsible for the toxicity of these proteins. This makes them strong candidates as therapeutic targets. However, due to their

Orthostatic blood pressure reactions and resting heart rate in relation to lung function - the Swedish CArdioPulmonary bioImage Study (SCAPIS)

BACKGROUND: There is a well-known comorbidity between chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD) which is only partially explained by common risk factors. Markers of cardiovascular autonomic dysfunction (CVAD), such as orthostatic hypotension and increased resting heart rate, are strongly associated with CAD. The autonomic nervous system also innervates the airw

Diagnostic Performance of Clinical and Routine Laboratory Data in Acute Mesenteric Arterial Occlusion—An International Multicenter Study

first_pageDownload PDFsettingsOrder Article ReprintsOpen AccessArticleDiagnostic Performance of Clinical and Routine Laboratory Data in Acute Mesenteric Arterial Occlusion—An International Multicenter Studyby Yasmin Soltanzadeh-Naderi 1ORCID,Annika Reintam Blaser 2,3ORCID,Martin Björck 2,4,Alexandre Nuzzo 5ORCID,Joel Starkopf 2,6,Alastair Forbes 2,Marko Murruste 2,6ORCID,Kadri Tamme 2,6ORCID,Peep

D-Dimer in Acute Mesenteric Venous Thrombosis: A Prospective Case-Control International Multicenter Study

Background:Acute mesenteric venous thrombosis (MVT) is rarely suspected as primary diagnosis in emergency departments and still carries an in-hospital mortality rate of above 20%.Objectives:The aim of this study was to find differences in clinical and laboratory markers between patients with acute MVT and a control group of suspected but confirmed as not having any type of acute mesenteric ischaem

Opium of the People? : Religious Politics in the Xi Jinping Era

This chapter discusses how the official religious policies stipulated in the so-called Document 19 issued by the Central Committee of the Chinese Communist Party in 1982 have transformed into the current religious laws and policies under Xi Jinping. Therefore, it analyses the most recent amendment (2017) of the Religious Affairs Regulations (RAR), Administrative Measures for Religious Groups (2020

History of cellular grafting for central nervous system repair—A clinical perspective

As late as in the 1970s, the evidence supporting that brain function might be restored by replacing dead cells by transplantation of new healthy cells was scarce in experimental animals and lacking in humans. Repairing the human brain was regarded as completely unrealistic by clinicians. Fifty years later, the situation is very different, and cellular grafting has reached patient application in se

The history of entrepreneurship education in the United Kingdom : 1860-2020

This paper examines the history of entrepreneurship education (EE) in the United Kingdom (UK), exploring different forms and types as they have emerged over time. The study uses a wide range of sources, including both secondary (e.g. published papers, historical records of specific programmes, and enterprise policy documents) and primary accounts that document the lived experience of educators. It

Multi-Target Sonar Localization Using an Optimal Mass Transport Framework

This article addresses the problem of multi-target localization from acoustic time delay measurements in a 3-D underwater environment, taking into account the depth-dependent sound speed of the underwater wave propagation. Specifically, we formulate the problem as an optimal mass transport (OMT) optimization over a grid of potential candidate positions. By exploiting an iterative refinement approa