Gamma-aminobutyric acid (GABA) is known for its multiple physiological functions, including beneficial effects against several metabolic disorders. This study explores enzymatic strategies to enhance the functional value of Andean seeds, specifically tarwi (Lupinus mutabilis), cañihua (Chenopodium pallidicaule) and quinoa (Chenopodium quinoa) real varieties, by converting their naturally occurring

PURPOSE: Four-pool Voigt (FPV) machine learning (ML)-based fitting for Z-spectra was developed to reduce fitting times for clinical feasibility in terms of on-scanner analysis and to promote larger cohort studies. The approach was compared to four-pool Lorentzian (FPL)-ML-based modeling to empirically verify the advantage of Voigt models for Z-spectra.METHODS: Voigt and Lorentzian models were fitt

Nature-based solutions, such as urban green spaces, are shown to contribute to carbon emissions reduction and carbon sequestration, and also to have valuable indirect effects and behavioural impacts. Implementing such solutions could achieve carbon neutrality within the decade in several major cities in Europe.

Adapting successes of policy transition from one city to another has been more difficult than single case of successful sustainability-driven projects and developments. A thorough understanding of local biophysical and socio-economic conditions is essential in formulating effective development plans and policies. Here, we propose the use of a social-ecological model as a comparative tool to help u

Climate change poses a threat to cities. Geospatial information and communication technology (Geo-ICT) assisted planning is increasingly being utilised to foster urban sustainability and adaptability to climate change. To fill the theoretical and practical gaps of urban adaptive planning and Geo-ICT implementation, this article presents an urban ecosystem vulnerability assessment approach using in

In the context of accelerated urbanization, socioeconomic development, and population growth, as well as the rapid advancement of information and communication technology (ICT), urban land is rapidly expanding worldwide. Unplanned urban growth has led to the low utilization efficiency of land resources. Also, ecological and agricultural lands are continuously sacrificed for urban construction, whi

The search for drugs that modulate NMDA receptors has been very active in the latest decades since they play a pivotal role in neuronal death and in several neurological conditions, including stroke, traumatic brain injury, and neurodegenerative diseases. Activating the receptor evokes an entry of calcium into the neuron, thus leading to a rapid depolarization that can be measured using electrophy

As global climate change intensifies, the question of what makes a place habitable or uninhabitable is critical, particularly in the context of a potential future climate outside the realm of lived experience, and the possible concurrent redistribution of populations partly associated with such climatic shifts. The concept of habitability holds the potential for advancing the understanding of the

The life of cutting tool inserts is critically important for efficient machining, reducing manufacturing cost, embedded energy, and enabling more complex parts to be machined. For these applications, cemented carbide (WC-Co) materials are a prime candidate. The performance of these materials can be limited by early fracture, typically via an intergranular fracture path with respect to carbide grai

We study the problem of computing the Voronoi diagram of a set of.n2 points with.O(log n)-bit coordinates in the Euclidean plane in a substantiallysublinear in . n number of rounds in the congested clique model with . n nodes.Recently, Jansson et al. have shown that if the points are uniformly at random distributed in a unit square then their Voronoi diagram within the square can be computed in.O(