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Molecular lineage diversity in the nearly-cosmopolitan Hiatella (Mollusca, Bivalvia) : assessing inter-oceanic relationships on multiple timescales.

Hiatella is one of the most widespread marine bivalve genera, occurring in diverse habitats from the temperate to polar latitudes in both hemispheres, and in fossil strata since almost 150 Myr ago. Despite variation in some biological and morphological traits, characters to resolve the current systematic structure consistently across the range of the genus are not known: all samples are often refe

Phylogeography of amphi-boreal fish : Tracing the history of the Pacific herring Clupea pallasii in North-East European seas.

BackgroundThe relationships between North Atlantic and North Pacific faunas through times have been controlled by the variation of hydrographic circumstances in the intervening Arctic Ocean and Bering Strait. We address the history of trans-Arctic connections in a clade of amphi-boreal pelagic fishes using genealogical information from mitochondrial DNA sequence data. The Pacific and Atlantic herr

Waste policies gone soft : An analysis of European and Swedish waste prevention plans

This paper presents an analysis of European and Swedish national and municipal waste prevention plans to determine their capability of preventing the generation of waste. An analysis of the stated objectives in these waste prevention plans and the measures they propose to realize them exposes six problematic features: (1) These plans ignore what drives waste generation, such as consumption, and (2

Reinforcement Learning for 4-Finger-Gripper Manipulation

In the framework of robotics, Reinforcement Learning (RL) deals with the learning of a task by the robot itself. This paper presents a hierarchical planning approach in which the robot learns the optimal behavior for different levels. For high-level discrete actions, Q-learning was chosen, whereas for the low level we utilize Policy Improvement with Path Integrals (PI^2) algorithm to learn the par

Family adjustment to diabetes diagnosis in children : Can participation in a study on type 1 diabetes genetic risk be helpful?

Background: Diagnosis of type 1 diabetes often causes a negative psychological impact on families. We examined whether parents and children enrolled in The Environmental Determinants of Diabetes in the Young (TEDDY) study differ in their psychological adjustment to diabetes diagnosis compared to children diagnosed with diabetes in the community. Methods: TEDDY follows 8676 children at genetic risk

Effect of metformin on plasma metabolite profile in the Copenhagen Insulin and Metformin Therapy (CIMT) trial

Aim: Metformin is the first-line treatment for Type 2 diabetes. However, not all people benefit from this drug. Our aim was to investigate the effects of metformin on the plasma metabolome and whether the pretreatment metabolite profile can predict HbA1c outcome. Methods: Post hoc analysis of the Copenhagen Insulin and Metformin Therapy (CIMT) trial, a multicentre study from May 2008 to December 2

Endocrine disruptors and testicular function

Despite concerns of the scientific community regarding the adverse effects of human exposure to exogenous man-made chemical substances or mixtures that interfere with normal hormonal balance, the so called “endocrine disruptors (EDs)”, their production has been increased during the last few decades. EDs' extensive use has been implicated in the increasing incidence of male reproductive disorders i

High levels of genetic diversity in marginal populations of the marsh orchid Dactylorhiza majalis subsp. majalis

Because of harsh conditions, suboptimal habitat quality and poor connectivity to other populations, plant populations at the margin of a distribution are expected to be less genetically diverse, but to be more divergent from each other than populations in the centre of a distribution. In northern Europe, northern marginal populations may also be younger than populations further to the south, and m

A 1.8Gb/s 70.6pJ/b 128×16 link-adaptive near-optimal massive MIMO detector in 28nm UTBB-FDSOI

This work presents a 2.0mm2 128×16 massive MIMO detector IC that provides 21dB array gain and 16x multiplexing gain at the system level. The detector implements iterative expectation-propagation detection (EPD) for up to 256-QAM modulation. Tested with measured channel data [1], the detector achieves 4.3dB processing gain over state-of-the-art massive MlMo detectors [2, 3], enabling 2.7x reduction

The Genetics of Urinary Tract Infections and the Innate Defense of the Kidney and Urinary tract

The urinary tract is a sterile organ system. Urinary tract infections (UTIs) are common and often serious infections. Research has focused on uropathogen, environment, and host factors leading to UTI pathogenesis. A growing body of evidence exists implicating genetic factors that can contribute to UTI risks. In this review, we highlight genetic variations in aspects of the innate immune system cri