Popular Abstract in Swedish Typ 2 diabetes är en av världens vanligaste och snabbast ökande kroniska sjukdomar. Sjukdomen är smygande och ger ofta inledningsvis inte några särskilda symptom. Den kan därigenom förbli oupptäckt under många år. Typ 2 diabetes är dock en allvarlig sjukdom; överdödligheten i hjärt-kärlsjukdomar är fyra gånger högre hos patienter med typ 2 diabetes än hos dem som inte hTo examine cardiovascular risk factors, glycaemic control and survival in patients with type 2 diabetes mellitus (T2DM) treated in primary care, patients with T2DM and a randomised age-stratified sample of men and women aged ≥40 years living in the same community were surveyed 1992-1994. ß–Cell function and insulin resistance were estimated using the Homeostasis Model Assessment (HOMA). Vital stat

The aims of this study have been focused on the identification of cell surface structures involved in the induction and regulation of apoptosis. Monoclonal antibodies against the major histocompatibility complex class I (MHC-I) were shown to induce apoptosis when cross-linked on the cell surface of different malignant cells having a pre-B or a myeloid precursor phenotype. The apoptotic response wa

In 1637 the Swedish Crown, encouraged by Dutch merchants, developed a plan to establish a colonial outpost in America to tap into profitable tobacco and beaver pelt trade. The same year the first cargo ships left Sweden and sailed westwards to claim their piece of America along the Delaware River. Although in many ways unsuccessful and short-lived (the colony collapsed in 1656), New Sweden became

This textbook in structural mechanics is based on the methodology of the finite element method. The understanding of basic elements of structural mechanics - springs, bars, beams and foundations - is gradually built up in one, two and three dimensions. Using these elements it is demonstrated how complex load-bearing structures can be modelled and analysed. Methods for linear as well as geometric a

The aim of this report is to identify the role of academics as entrepreneurs. Education and a highly educated staff is a growth factor in companies and in this report we will highlight the characteristics of companies established by academics and which factors are crucial for these companies to grow. A special focus has been whether academics organise their companies in a particular way – a way th

Det här kapitlet diskuterar och analyserar digitaliseringen av det vetenskapliga publiceringssystemet, framförallt i relation till peer review-processen och Open Access (OA). I vilken utsträckning är exempelvis tillit till vetenskaplig forskning, uttryckt i publikationer, rättfärdigat och hur kan den bedömas? Kapitlet använder sig av exemplet där vetenskapsjournalisten John Bohannon avslöjade bris

Popular Abstract in Swedish I detta avhandlingsarbete studerades mekanismer underliggande utveckling av multipel organdysfunktion (MODS), med fokusering på intercellulär proinflammatorisk reglering och adhesionmolekylers roll vid den fortsatta utvecklingen av organskada samt att studera eventuella organspecifika skillnader. Målsättningen var att finna nya behandlingar och prevention mot utvecklingIntestinal I/R is considered to be an important initiating event in several pathophysiological conditions such as trauma, bleeding, sepsis and pancreatitis, frequently leading to concomitant both single and potentially multiple organ dysfunction. The purpose of this thesis was to study mechanims underlying the development of multiple organ dysfunction, with special focus on intercellular proinflam

Yta är, paradoxalt nog, ofta något grundläggande i receptet för framgång i dagens ekonomiska system. Utseende, klädsel, attityd och attribut är centrala element i det som Erving Goffman kallar impression management: förmågan att avge ”rätt” intryck med hjälp av välformulerade självpresentationer som, baserade på statussymboler och associationer, indikerar vem man är eller vill vara (se Goffman 195

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