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Immuno-modulatory functions of CD1d-restricted natural killer T cells

Popular Abstract in Swedish Syftet med min avhandling är att utforska vilken funktionell roll naturliga mördar T (NKT) -celler har, samt vilka gener som är viktiga för dessa celler. NKT-celler utgör en liten men specialiserad undergrupp av T-celler, och är mycket intressanta eftersom att de, trots att de tillhör det specifika immunförsvaret, även har receptorer och egenskaper som är starkt förknipThis thesis focuses on a small population of non-conventional T lymphocytes, called natural killer T (NKT) cells. NKT cells have many unique features; such as recognition of glycolipids presented by CD1d, expression of NK receptors and rapid production of large amounts of cytokines, such as IL-4 and IFN-gamma,?upon activation. This early and robust cytokine burst is believed to give NKT cells the

Varseblivningstid och reaktionstid vid utrymning. Sammanställning av enkätundersökning gällande för varuhus, restaurang och danslokal

En enkätundersökning har genomförts bland brandingenjörer i Sverige med syftet att få information om detektionstider samt reaktions- och beslutstider vid en utrymning av tre olika lokaltyper; varuhus, restaurang och danslokal/nattklubb. Reslutaten kan ligga till grund för fortsatta studier för att bestämma partialkoefficienter för dimensionering av de gångvägar som används vid utrymning. Den ger o

Simulation of Particle Morphology Development Under Kinetically Controlled Conditions

We have developed software, called UNHLATEXTM> KMORPH, for predicting particle morphology development under conditions of kinetic control. In order to accomplish this, one must first simulate the polymerization kinetics and as a result KMORPH has developed into a fairly complete model for seeded emulsion polymerization kinetics. The simulation takes into account both the aqueous phase and particle

Simulated harvesting of stream salmonids with a seasonal life history

We assessed the influence of timing of harvests on an age-structured population by altering the order of the harvest in relation to density-dependent recruitment and winter mortality. To analyze the effects of harvest timing on a general population of stream salmonids with five age-classes, we used three management strategies: no minimum size limits and two minimum size limits with increasing degr

Improving radioimmonotargeting of tumors. Variation in the amount of L6 MAb administered, combined with an immunoadsorption system (ECIA)

Extracorporeal immunoadsorption (ECIA) is a new method for the selective removal of circulating radiolabeled monoclonal antibodies (MAb) from plasma to increase the uptake in tumor versus normal tissues (T/N-ratio). To ascertain whether the amount of MAb affects T/N ratios immediately and 24 h after ECIA, we used a rat model with two tumor sites--one intramuscular (im) and one below the subrenal c

Coherent Interactions in Rare-Earth-Ion-Doped Crystals for Applications in Quantum Information Science

Popular Abstract in Swedish Den här avhandlingen handlar om hur kristaller, som innehåller en liten mängd av ämnen tillhörande gruppen sällsynta jordartsmetaller, kan användas för forskning och tillämpningar rörande kvantinformation. Genom att belysa kristallerna med laserljus kan atomernas tillstånd styras och studeras. I avhandlingen diskuteras olika aspekter av hur de sällsynta jordartsatomer sThis thesis describes investigations of the use of cryogenically cooled rare-earth-ion-doped crystals for quantum information processing and quantum optics. Several aspects of the coherent interaction between light and rare-earth ions in solids are addressed. Quantum information science has given physicists new views of quantum mechanics. The transmission of quantum states has already found pract

Frontotemporal dementia – Differentiation from Alzheimer's disease

Organic dementia is dominated by primary degenerative disorders such as Alzheimer’s disease (AD) and frontotemporal dementia (FTD). FTD is a distinct clinical syndrome with behavioural, personality, emotional and language disturbances preceding the cognitive decline. This clinical presentation is distinctly different from that of AD which is characterized by early cognitive changes, such as memory

Modeling the acid-base properties of bacterial surfaces: A combined spectroscopic and potentiometric study of the gram-positive bacterium Bacillus subtilis

In this study, macroscopic and spectroscopic data were combined to develop a surface complexation model that describes the acid-base properties of Bacillus subtilis. The bacteria were freeze-dried and then resuspended in 0.1 M NaCl ionic medium. Macroscopic measurements included potentiometric acid-base titrations and electrophoretic mobility measurements. In addition, ATR-FTIR spectra of wet past

Water balance change for a re-vegetated xerophyte shrub area

Water balances for a re-vegetated xerophyte shrub (Caragana korshinskii) area were compared to that of a bare surface area by using auto-weighing type lysimeters during the 1990-1995 growing seasons at the southeast Tengger Desert, Shapotou, China. The six-year experiment displayed how major daily water balance components might vary for a bare and a re-vegetated sand dune area. Evapotranspiration

The Bryophyte flora of Scanian sand-steppe vegetation and its relation to soil pH and phosphate availability

The sand-steppe is a vegetation type mainly found in the southern Baltic region on calcareous sand dominated by vascular plants such as Koeleria glauca, Dianthus arenarius ssp. arenarius and Astragalus arenarius. Eighty-eight plots representing most sand-steppe sites in Scania, southernmost Sweden, were analyzed with respect to bryophytes, pH and exchangeable phosphate in the topsoil. The most com

Förmaksflimmer - ny kunskap ger nya behandlingsmöjligheter

Atrial fibrillation (AF) is the most common cardiac arrhythmia prompting treatment. Advances in our knowledge of the pathophysiology of AF provide the basis for new and improved treatment modalities. Thus, focal excitation and localised impulse conduction defects are possible trigger factors which can be counteracted by focal ablation and pacing synchronisation, respectively. Perpetuation of AF, c

The Marriage of Ego and Id. Cognitive Integration and its Relation to Mystical Experience

Abstract in UndeterminedThe author suggests a new model for interpretation of mystical experience, based on a fruitful combination of cognitive psychology and depth psychology. Offering a rather wide definition of mystical experience, the author then turns to two basic assumptions—a general systems approach and an organismic-holistic view of development. Hans Loewald's analysis of primary process