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Acquired chromosome abnormalities in tumours often reflect pathogenetic events at the gene level. Multicolour fluorescence in situ hybridisation (FISH) with single-copy probes offers extensive possibilities to characterise chromosome breakpoints in relation to the physical map of the human genome. This approach is based on the construction of comprehensive EST- based maps, combinatorial labelling

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING Ett gott mål mat (enteral nutrition) och en välfungerande mag-tarmkanal från mun till brunn är för de flesta en självklarhet men för vissa mer en önskvärdhet. Vid sjukdom i tarm eller bukhåla kan det hända att ett tarmavsnitt nödga's koppla's ur den normala kontinuiteten genom anläggande av en så kallad stomi. Vid överviktskirurgi (exAbolition of enteral nutrition is sometimes required in severe illness. The primary aim of the present work has been to elucidate possible changes in intestinal morphology and motor function in absence of enteral nutrition. Total absence of enteral nutrition in an isolated intestinal segment was created by bypassing the distal ileum in a rat model. Intestinal bypass causes marked circumferential a

Purpose: We critically examined the evidence supporting the widely accepted notion that patients undergoing continent urinary tract reconstruction after cystectomy experience superior quality of life outcomes than patients receiving a conduit. Materials and Methods: Based on a comprehensive MEDLINE literature search we retrieved and evaluated all full-length articles published in the English, Fren

The formation process of SBA-15 has been investigated by time resolved TEM, in-situ SAXS/SAXD and in-situ NMR. The synthesis was done at 35 degrees in acidic solution with tetramethylorthosilicate as the silica source and Pluronic P123 as the structure directing amphiphile. The initially formed silica-polymer composite consists of flocs of spherical micelles in a silica matrix. The micelles then c

The recognition of bacterial lipopolysaccharide (LPS) is principally mediated by either membrane-bound or soluble form of the glycoprotein CD14 and CD14-associated signal transducer, toll-like receptor 4 (TLR4). Recent findings indicate that the serine protease inhibitor, alpha 1-antitrypsin (AAT), may not only afford protection against proteolytic injury, but may also neutralize microbial activit

The issue of this article is the direction of the Swedish compulsory school. The article is based upon the results of a longitudinal study of four schools participating in a probation, initiated by the Swedish government, where they are allowed to work without the timetable. What regulates school activity when there is no timetable that prescribes the amount of time for each subject? What are the

Sommaren är loppmarknadernas tid. I trakten där jag bor är det vanligt med någon loppmarknad varje helg. Det är stora tillställningar där den arrangerande idrotts- eller hembygdsföreningen under ett år har samlat in begagnade grejer som säljs till mycket låga priser. För många föreningar är vinsten från försäljningen en viktig post i budgeten. Poängen med loppmarknaden är att föremål som i någons

Popular Abstract in Swedish Avhandlingen analyserar romanen "Lustgården" av den ryska författaren Nina Sadur (på ryska 1997, på svenska 2001). Feministisk litteraturteori används för att problematisera receptionen av Sadurs verk samt för att motivera valet av verk för analys. Avhandlingen är indelad i två delar: Del ett presenterar en linjär läsning av romanen, där den läses som ”avikande diskursThis doctoral dissertation is an analysis of the novel 'The Garden' (1997), by the Russian author Nina Sadur. Drawing on feminist literary criticism, it aims at providing a woman-authored text with the in-depth study the novel’s literary sophistication calls for. The dissertation is divided into two parts: Part One presents a linear reading of the novel in which it is read as ‘aberrant discourse’

A numerical synthesis method for optimally robust control isproposed. The method applies to the case of linear dependenceon uncertain parameters in the characteristic polynomial. Aprimal/dual pair of infinite-dimensional convex problems is solvedby successive finite-dimensional approximations. The primal/dualpair has no duality gap, and both upper and lower bounds produced by theapproximations con

This dissertation considers two different aspects of health economics; (i) stated preference methods and (ii) empirical analyses of equity. The first essay deals with the issue of the choice of econometric models when analysing data from a closed-ended contingent valuation survey in health economics. The features of provision, either compulsory or voluntary, and the fact that certain individuals m

Managing hemophilia becomes particularly difficult in patients with inhibitory antibodies, especially in those requiring surgery or with refractory bleeding events. Equally challenging are those patients who develop autoantibodies against factor VIII (FVIII) in the absence of a prior history of FVIII deficiency (acquired hemophilia). Physicians seeking both short- and long-term treatment strategie

The monoclonal antibody 10E4, which recognizes an epitope supposed to contain N-unsubstituted glucosamine, is commonly used to trace heparan sulfate proteoglycans. It has not been fully clarified if the N-unsubstituted glucosamine is required for antibody recognition and if all heparan sulfates carry this epitope. Here we show that the epitope can contain N-unsubstituted glucosamine and that nitri

1 The immunomodulator Linomide has been shown to protect against septic liver injury by reducing hepatic accumulation of leukocytes although the detailed anti-inflammatory mechanisms remain elusive. This study examined the effect of Linomide on the production of CXC chemokines, including macrophage inflammatory protein-2 (MIP-2) and cytokine-induced neutrophil chemoattractant (KC) and interleukin-

A high precision, time-of-flight hodoscope has been constructed to analyse the secondary pion beam at GSI, Darmstadt. The hodoscope comprises three scintillator planes with the individual scintillator rods read out by photomultipliers in both ends. A new active base of the emitter follower type has been developed for stabilization of voltages at the last dynodes of the photomultiplier. The time re

Control methods are being used increasingly for uncertainty management and QoS in modern web server systems. Previous approaches have suggested combined feed-forward and feedback control strategies, using queuing theory for feed-forward delay prediction. While queuing theory allows one to predict delay as a function of arrival and service rates, the prediction applies only to long-term averages, a

In this paper, a number of challenges, which need to be overcome if multivariate monitoring of wastewater treatment operation is to be successful, are presented. For each challenge, one or several solutions are discussed. The methodologies are illustrated using an example from full-scale wastewater treatment operation. Some guidelines regarding choices of methods and implementation aspects are giv

Popular Abstract in Swedish Medievärlden är idag föremål för drastiska förändringar. Förutom de traditionella medierna såsom böcker, TV och radio, introduceras interaktiva digitala medier. Dessa förändringar berör inte mins barnens och ungdomarnas liv. Allteftersom de får tillgång till sofistikerade elektroniska och digitala medier blir deras fritid alltmer teknifierad. Vi är all medvetna om hur mWe are all aware of how many different media have become a familiar equipment in the home, perceived as any other furnityre. The media have become more or less unconsciously intertwined in everyday routines. As the media environment is continously in a phase of transformation, it is crucial to gain knowledge about children´s and adolescents´own understanding and interpretation of their mediarelate