Objective. To construct a database for clinical epidemiological prostate cancer research based on linkages between the National Prostate Cancer Register (NPCR) of Sweden, a population-based, nationwide quality database, and other nationwide registries. Material and methods. By use of the individually unique Swedish Personal Identity Number, the NPCR was linked to the Swedish Cancer Registry, the C

Inclusive transverse momentum spectra of primary charged particles in Pb-Pb collisions at root s(NN) = 2.76 TeV have been measured by the ALICE Collaboration at the LHC. The data are presented for central and peripheral collisions, corresponding to 0-5% and 70-80% of the hadronic Pb-Pb cross section. The measured charged particle spectra in |eta| < 0.8 and 0.3 < p(T) < 20 GeV/c are compared to the

This thesis is based on 5 papers exploring the filtering problem in non-linear non-Gaussian state-space models together with applications of Sequential Monte Carlo (also called particle filtering) methods to the positioning in wireless networks. The aim of the first paper is to study the performance of particle filtering techniques in mobile positioning using signal strength measurements. Two di

Popular Abstract in Swedish Barn födda före 32 gestationsveckor, även de utan svåra neurologiska avvikelser, har en hög förekomst av neuropsykologiska problem såsom läs-, inlärnings-, språk-, minnes- och beteendeproblem. Det är ännu inte klarlagt vilka funktionella och strukturella förändringar i hjärnan som orsakar dessa problem. Möjligheten till tidig diagnos behövs men saknas ännu. Auditiva hänChildren born before 32 gestational weeks have a high incidence of neuropsychological deficits. The structural and functional correlates of such impairments in preterm infants are incompletely understood, and early diagnostic tools are needed, but still lacking. Auditory event-related potentials (AERPs) are neurophysiological measures of cortical sound detection, encoding, discrimination, and atte

I samband med årets internationella mykologikongress IMC9 i Edinburgh anordnade IAL, International Association for Lichenology, en veckas lavexkursion på den skotska västkusten under ledning av Chris Ellis och Brian Coppins, den senare en av världens främsta lavexperter. Martin Westberg och Ulf Arup var med och skådade oceaniska rariteter.

Autism spectrum disorders (ASD) are classified as neurological developmental disorders. Several studies have been carried out to find a candidate biomarker linked to the development of these disorders, but up to date no reliable biomarker is available. Mass spectrometry techniques have been used for protein profiling of blood plasma of children with such disorders in order to identify proteins/pep

Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world. It is an Epstein-Barr virus-associated malignancy with an unusual racial and geographical distribution. The host innate immune sensor genes play an important role in infection recognition and immune response against viruses. Therefore, we examined the association between polymorphisms in genes within a group of pattern

Aims: The purpose of this study was to describe and analyse the effects of health-promoting educational interventions among employees in a municipality in Sweden. Methods: A randomized controlled educational intervention study was performed with 340 employees. Supervisors and workplace champions took part in two separate educational programmes with focus on health promotion. Intervention groups we

Abstract For activity quantification based on planar scintillation camera measurements, photon attenuation is an important factor that needs to be corrected for in a patient- and organ-specific manner. One possibility for obtaining attenuation correction maps is to use X-ray CT scout images. Since the intensity of scout images is in relative numbers, their image values need to be multiplied by a f

The t(12;21) translocation generates the ETV6/RUNX1 fusion gene, present in 25% of childhood acute lymphoblastic leukemia. This fusion gene is important for leukemia development but is not sufficient for leukemia to arise. Hence, the additional genetic changes present in leukemic ETV6/RUNX1-positive cells give important clues regarding the history of the leukemia. The aim of this thesis has been t

Kursguider är en text som finns mellan kursplanens målformuleringar och själva genomförandet av en kurs. Den skrivs om för varje kurstillfälle för att anpassas till datum och specifika examinationsformer. Som undersökningsmaterial är kursguider därmed mycket praktiknära och ger mycket god insyn i hur undervisning är tänkt att ske. Trots detta har ingen tidigare forskning gjorts i Sverige kring det

The soluble form of the urokinase receptor, suPAR, has been suggested as a novel biomarker of low-grade inflammation. Activation of the immune system has been proposed to contribute to the development of depression and suicidal behavior. In order to identify depressed and suicidal individuals who could benefit from an anti-inflammatory treatment, a reliable biomarker of low-grade inflammation is v

In this review, we analyze several types of graphene-based sensors for glucose detection with respect to their preparation, properties and efficiency in electro-chemical processes. Graphene may display different types of defects, which play a role in the electron transfer processes. Oxygenated groups on the edges of graphene planes reduce the graphene in-plane conductivity, but may enhance the het

This paper presents an iterative decoder for faster-than-Nyquist (FTN) and orthogonal signaling multi-carrier systems. FTN signaling is a method of improving bandwidth efficiency at the expense of higher processing complexity in the transceiver. The decoder can switch between orthogonal and FTN signaling modes and exploits channel properties to improve bandwidth efficiency. The decoder is fabricat

OBJECTIVE - We assessed the association between A1C and cardiovascular diseases (CVDs) in an observational study of patients with type 1 diabetes followed for 5 years. RESEARCH DESIGN AND METHODS - A total of 7,454 patients were studied from the Swedish National Diabetes Register (aged 20-65 years, diabetes duration 1-35 years, followed from 2002 to 2007). RESULTS - Hazard ratios (HRs) for fatal/n

Background: High-dose chemotherapy (HDT) was added to conventional chemotherapy in Ewing sarcoma family tumor (EFT) patients, poor responders (PRs) to induction chemotherapy in order to improve their survival. Patients and methods: Patients aged

Popular Abstract in Swedish Bröstcancer är kvinnans vanligaste cancerform och globalt sett den cancer som leder till flest dödsfall. Bröstcancerscreening med mammografi används därför i syfte att hitta cancern tidigt. En tidigt upptäckt cancer har oftast en bättre prognos med möjlighet att minska dödligheten i bröstcancer. Mammografitekniken är dock behäftad med vissa begränsningar vad gäller känsAbstract: Mammography is currently the established method in breast cancer screening, although the sensitivity is known be affected by overlapping tissue concealing tumours. Breast tomosynthesis takes advantage of multiple exposures at different angles reducing the negative effect of obscuring tissue. The aim of this thesis was to investigate the use of tomosynthesis in breast imaging with a spec