Popular Abstract in Swedish Microarray-tekniken som har utvecklats under cirka ett decennium, har gett oss nya möjligheter att studera aktiviteten av tusentals gener samtidigt. Det är aktiviteten hos generna, eller uttrycket av generna, som karakteriserar en cell. Celler som tillhör olika organ, eller som befinner sig i olika omgivningar har karakteristiska genuttrycksmönster. Det som gör microarrThe technology of cDNA microarrays has given us the possibility to monitor the state of cells by measuring the activity of thousands of genes simultaneously. This high-throughput techniqe has in cancer research allowed exploratory studies of molecular mechanisms behind for example metastasis and response to therapy. This increased knowledge can hopefully result in new therapies and improved progno

The small heat shock proteins (sHsps) are a widespread class of molecular chaperones existing in all organisms. During heat stress the sHsps protect other proteins from unfolding and aggregation. In plants the sHsps play an especially prominent part of the stress response. In this thesis chemical crosslinking and mass spectrometric mapping of crosslinked peptides has been used to investigate the

Abstract in Undetermined Artikeln undersöker möjligheten att utifrån ett feministiskt och genus- teoretiskt perspektiv verka som relativt nyetablerad och yrkesverksam i den akademiska världen. Artikelförfattarna diskuterar utifrån den gemensamma erfarenheten av det pedagogiska utvecklingsprojektet ”Implementering av ett kritiskt genusperspektiv” lett av Anna Lena Lindberg. De lyfter fram hennes be

This is a mapping of my upcoming project on the field of short culture phenomena. One part of that will deal with the music videos of Lady Gaga. In this book chapter I present som basic information on Lady Gaga, and suggestions on how to approach the artist and her artistic/aesthetic expressions. Scenes, stage performance, media, and the different relation to the fans is put into focus, and I mean

As distributed systems continue to evolve, automatic resource management is becoming more and more impor tant. The resource management system must be able to dynamically handle large heterogeneous systems in a way that gives good performanceand resource utilization. In the performance context, allocating software modules to nodes in an efficient way is of high interest. This paper considers the pr

Firms began to abandon the “silo” approach to risk management for more integration in the risk management system. Enterprise risk management (ERM) emerged as a framework for the management of integrated risks in a strategy setting supported by risk governance. Practically and empirically there has been no real consensus about what an ERM firm looks like. ERM frameworks provide a variety of concept

We examine the role of substitution from traditional to modern energy carriers and of differential rates of innovation in the use of each of these in Sweden from 1850 to 1950. We use a simple growth model with a nested CES production function and exogenous factor augmenting technological change and carry out a growth accounting decomposition based on the econometric results. Energy and energy

The clinical pharmacology of desmopressin and a new vasopressin analogue (F992) was investigated in healthy human subjects. The common procedure of overhydration of healthy volunteers when studying the antidiuretic effect of a drug, may affect the pharmacokinetics, in particular the volumes of distribution. Hence, the estimated parameters may not be relevant to euhydrated patients. F992 was found

Popular Abstract in Swedish En kontinuerlig alkoholkonsumtion leder till en ökad tolerans för alkohol (dvs en allt större dos krävs för att uppnå samma effekt) och kan slutligen också leda till ett alkoholberoende. Alkoholism är ett betydande samhällsproblem och en personlig tragedi för de som drabbas och deras omgivning. Alkohol har till skillnad från andra beroendeframkallande droger som tex koAlcohol induces profound effects on the function of the nerve cells in the nervous system. Alterations in gene expression is an important way by which these effects could be induced and sustained. Activating Protein-1 (AP-1) is a dimeric transcription factor constituted of proteins from the fos and jun immediate-early gene families. AP-1 induces gene expression of genes having a functional AP-1 bi

Laser diagnostics have become state of the art tools for locally measuring droplet size, velocity and temperature in atomizing sprays. However, when applied in optically dense situations, these techniques suffer from measurement errors induced by unwanted effects such as laser intensity reduction along the path of propagation (light extinction), attenuation in signal intensity collected by the det

Abstract is not available