Prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) is effective against prostate cancer (PCa), but all patients relapse eventually. Poor understanding of the underlying resistance mechanisms represents a key barrier to development of more effective RLT. We investigate the proteome and phosphoproteome in a mouse model of PCa to identify signaling adaptations triggered by P

This article addresses the intricate and previously untold story of a German attempt in 1944 to have an agent, the Latvian Voldemar Blankenfelds, dispatched by boat, via Sweden, to South America where a German intelligence network was being established. Shortly after his arrival in Sweden in June 1944, however, Blankenfelds got in touch with the British diplomatic mission in Stockholm, told them o

The last 20 years have witnessed a marked increase in Swedish participation in major international UN-, EU- and/or NATO-led armed missions mandated according to Chapter VII of the UN Charter. This development reflects the new foreign and security priorities of Sweden in the wake of the end of the Cold War. Decisions on Swedish participation in such missions, however, cannot be taken without parlia

Injectable bioelectronics could become an alternative or a complement to traditional drug treatments. To this end, a new self-doped p-type conducting PEDOT-S copolymer (A5) was synthesized. This copolymer formed highly water-dispersed nanoparticles and aggregated into a mixed ion-electron conducting hydrogel when injected into a tissue model. First, we synthetically repeated most of the published

While family members tend to have similar labor market outcomes, measuring the contribution of behavioral spillovers is difficult. To identify spillovers between brothers, we exploit Denmark's largest random assignment of young men—to eight months of military service, where service status of brothers is correlated, but draft lottery numbers are not. We find average spillovers of elder brother serv

Garden escapes of Acer campestre spread as a cryptic invading gene pools and challenge the conservation of a unique ancient population in southern Scandinavia. The native gene pool consists of just 34 individuals and is listed as critically endangered. This population is more than 150 years old and represents a unique diorama into an almost extinct genetic diversity of the early 19th century. That

This thesis investigates ultracold bosonic systems using an extended mean-field formalism with a focus on their superfluid and supersolid properties. The dissertation comprises five chapters and four articles, where the chapters provide some background to the research put forward in articles.Paper I demonstrates the existence of multiple singly-quantized vortices in two-dimensional droplets made o

Since 2011, Moroccan civil society actors have experienced an important political opening that has allowed them to play a much more direct and influential role in the process of policy-making. The National Dialogue that has taken place between the government and civil society in the writing of different pieces of legislation represents a demonstrable step towards increased participation and legiti

Aims: It is increasingly recognized that tools are required for assessing and benchmarking quality of care in order to improve it. The European Society of Cardiology (ESC) is developing a suite of quality indicators (QIs) to evaluate cardiovascular care and support the delivery of evidence-based care. This paper describes the methodology used for their development. Methods and results: We propose

Background and purpose - Hip surveillance in children with cerebral palsy (CP) includes repeated radiographic hip examinations and measurements of the hip migration percentage (MP) to identify hips in need of surgery early, to prevent dislocation with the fewest number of radiographic examinations possible. We analyzed the early development of the MP in hips operated on to prevent hip dislocation

Background and purpose - Intramedullary nails (IMN) have become increasingly common as treatment for trochanteric hip fractures (THF) although they are costlier, and without proven superiority compared with sliding hip screws (SHS). We investigated whether the 2 methods differ in terms of short-term mortality when used in fractures where both methods are suitable. Patients and methods - We extract