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Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program

OBJECTIVE: Genome-wide association studies have begun to elucidate the genetic architecture of type 2 diabetes. We examined whether single nucleotide polymorphisms (SNPs) identified through targeted complementary approaches affect diabetes incidence in the at-risk population of the Diabetes Prevention Program (DPP) and whether they influence a response to preventive interventions. RESEARCH DESIGN

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Abstract in Danish Artiklen viser, hvordan gerontologi er lavt prioriteret i uddannelser på bachelor-, diplom- og masterniveau (kandidat) i primært Danmark og Norge. Der tages udgangspunkt i et nordisk kortlægningsarbejde, som blev gennemført i 2008. Dette suppleres med danske og norske aktiviteter, som er kommet til, siden surveyen blev gennemført. Der argumenteres for, at et nyt kortlægningsarbe

Local exchange-correlation potentials

Recent advances in the many-body theory of electrons in solids and in the theory of the interacting electron gas are used to construct explicit local effective potentials which incorporate the effects of correlation and exchange. For ground state properties we consider the scheme by Hohenberg, Kohn and Sham and provide data for the effective potential μxc. For excitation energies the corresponding

Perturbed Learning Automata in Potential Games

This paper presents a reinforcement learning algorithm and provides conditions for global convergence to Nash equilibria. For several reinforcement learning schemes, including the ones proposed here, excluding convergence to action profiles which are not Nash equilibria may not be trivial, unless the step-size sequence is appropriately tailored to the specifics of the game. In this paper, we sides