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The actions and interactions of family genetic risk scores for alcohol use disorder and major depression on the risk for these two disorders

We know little about how genetic risk factors for two disorders jointly act and interact in predisposing to illness. Therefore, in the Swedish population, born 1970–1990 (n = 2,116,082) and followed through 2015, we examine, using additive Cox models, the impact of the family genetic risk scores (FGRS) for alcohol use disorder (AUD) and major depression (MD), their interaction with each other and

Interventions in child welfare : A Swedish inventory

In Swedish child welfare, there are no mandatory guidelines on what interventions to use. Local authorities are able to set their own criteria for implementing or designing interventions. We carried out a survey to identify interventions in use in Children's Social Services and Child and Adolescent Psychiatric Care in Sweden. A total of 102 interventions were stated to have been in use, with betwe

Effects of large particles in pipe flow at low and moderate Reynolds numbers

The presence of solid particles in a Newtonian liquid flow will affect the properties of the flow. For small particles these effects are fairly well understood. However, the behaviour of liquids laden with large particles are less well understood and even more so if the carrier liquid is a non-Newtonian fluid. In the present study we consider large particles of spherical shape. By large is here me

Analys av sju riksdagspartiers klimatpolitik utförd av klimat- och omställningsforskare : Sveriges klimatpolitik inför riksdagsvalet 2022 enligt Researchers’ Desk

● Syftet med denna rapport är att ge forskares analys av riksdagspartiernas klimatpolitik inför valet 2022.● Alla som har bidragit till denna rapport är klimat- eller omställningsforskare och medlemmar i Researchers’ Desk1.● Researchers’ Desk är en oberoende, ideell organisation, med över 80 ledande forskare i Sverige, som arbetar med olika aspekter av klimatförändringarna.● Alla de åtta politiska

Sticky Wages and the Great Depression: Evidence from the United Kingdom

How sticky were wages during the Great Depression? Although classic accounts emphasise the importance of nominal rigidity in amplifying deflationary shocks, the evidence is limited. In this paper, I calculate the degree of nominal wage rigidity in the United Kingdom between the wars using new granular data covering millions of wages. I find that nominal wages changed infrequently but that wage cut

Valvular heart diseases in immigrants and Swedish-born individuals : a national cohort study

Objectives. The aim of this study was to analyse the risk of valvular heart diseases among foreign-born individuals in Sweden. Design. This was a nationwide study of individuals aged 18 years of age and older (N = 6,118,649; 2,970,055 men and 3,148,594 women). Valvular heart diseases were defined as at least one registered diagnosis in the National Patient Register between 1 January 1998 and 31 De

General Process Simulations

Simulation of AM products can capture a number of aspects. Apart from the traditional types of simulation of the end product, such as mechanical, thermal and fluid analyses, it is possible to simulate the AM build process. While simulating products intended for AM can sometimes be performed in exactly the same way as with products intended for traditional manufacturing, there are several aspects t

A scoping review of interventions using occupation to improve mental health or mental wellbeing in adolescent populations

Introduction: Occupation-based interventions could help to address a growing mental health crisis among young people and adolescents. To develop new interventions and avoid research waste, a review of the academic literature is needed that systematically identifies and describes interventions designed to improve the mental health and wellbeing of 11–25 year-olds. Aim: The scoping review aims to sy

Experimental in vivo model to evaluate the impact of Cernitin™ on pain response on induced chronic bladder inflammation

Objective: Inflammation of the urinary bladder may cause burdensome pain also called bladder pain syndrome (BPS). A limitation in understanding BPS pathophysiology is the lack of appropriate preclinical model. Previously published clinical and preclinical studies revealed positive impact of Cernitin™ on pain relief in chronic prostatitis. The objective of this study was to evaluate the effects of

KiMoPack : A python Package for Kinetic Modeling of the Chemical Mechanism

Herein, we present KiMoPack, an analysis tool for the kinetic modeling of transient spectroscopic data. KiMoPack enables a state-of-the-art analysis routine including data preprocessing and standard fitting (global analysis), as well as fitting of complex (target) kinetic models, interactive viewing of (fit) results, and multiexperiment analysis via user accessible functions and a graphical user i

Does Water Quality Matter for Life Quality? A Study of the Impact of Water Quality on Well-being in a Coastal Community

Most studies of life quality are concentrated on a country-level scale, while local differences within a country or area are less studied. Thus, the effect of the environment on life quality on a local scale remains understudied and is often represented by one generalized common factor. In this study, we investigated the effect of an objectively measured environmental quality variable and subjecti

Fire behaviour of upholstered furniture component materials at multiple scales

In this research, both experimental test methods and computer models were used to characterise the thermal decomposition processes of selected upholstered furniture component materials, namely; flexible polyurethane foam and a range of different fabric coverings. This was first done at some of the smallest, simplest levels available, and how these materials were tested and the methods chosen to in