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Background: Bladder cancer is molecularly one of the most heterogenous malignancies characterized by equally heterogenous clinical outcomes. Standard morphological assessment with pathology and added immunohistochemical analyses is unable to fully address the heterogeneity, but up to now treatment decisions have been made based on such information only. Bladder cancer molecular subtypes will likel

Quaternary Asian low-latitude hydroclimate cyclicity has long been attributed to insolation forcing, in contrast to the dominant ice-sheet and CO2 controls identified in mid-high-latitude regions. However, debates exist regarding these rainfall variations and forcings due to inconsistent reconstructions and simulations. Here, by combining rainfall proxy records with multi-model simulations, domina

In this article, I challenge the increasing emphasis on digital technologies to enhance encounters with the past in heritage landscapes. Beginning with a memory from my childhood, I conceptualise presence as being there and review recent approaches in heritage studies that highlight the wide range of benefits derived from embodied experiences in heritage places including reinforcing feelings of we

During Achilles tendon healing in rodents, besides the expected tendon tissue, also cartilage-, bone- and fat-like tissue features have been observed during the first twenty weeks of healing. Several studies have hypothesized that mechanical loading may play a key role in the formation of different tissue types during healing. We recently developed a computational mechanobiological framework to pr

Journalistic live blogging entails the conundrum of capturing emotions in a context where they should be absent in order to snap up the sensational in the subtle drama of the courtroom and present it in a way that attracts readers, thus making it clickable.Applying an inductive frame analysis of live blogs and drawing on criteria of newsworthiness and an emotion sociological framework, this articl

This work investigates the multi-scale dynamics of the combustion system in a lean-burn spark ignition natural gas engine using different gas injection timings (GIT). The in-cylinder pressure time series are measured, and the indicated mean effective pressure (IMEP) time series are calculated. The influence of GIT on the combustion system is investigated through wavelet analysis, multi-resolution

A high-precision robot has been built for Max IV Laboratory in Lund, Sweden. The robot assists with marking 2D projections from computer-aided design (CAD) models onto floors. The second important function of the robot is floor scanning, which aids in a three-dimensional model correction during construction, production, and installation processes at large facilities. The robot provides accurate po

Multiconfiguration Dirac-Hartree-Fock (MCDHF) and relativistic configuration interaction (RCI) calculations are performed for 22 states in singly ionized tin (Sn II) belonging to the 5s2ns (n=6,7), 5s2nd (n=5,6), 5s5p2 even parity configurations and the 5s2np (n=5,6,7), 5s24f odd parity configurations. Valence-valence and core-valence correlation effects are taken into account through configuratio

This paper presents a four-stage algorithm for the realization of multi-input/multi-output (MIMO) switched linear systems (SLSs) from Markov parameters. In the first stage, a linear time-varying (LTV) realization that is topologically equivalent to the true SLS is derived from the Markov parameters assuming that the discrete states have a common MacMillan degree and a mild condition on their dwell

The high brilliance and coherent beams resulting from recent upgraded synchrotron radiation facilities open the way for a large range of experiments, where detectors play a key role in the techniques and methods developed to fully exploit the upgraded synchrotron. For instance, one of the major limitations of XAFS experiment is the performance of the detectors. In order to be able to measure more

Deep in the mountains near the Allegheny National Forest in Pennsylvania, USA lay the twisted ruins of the Kinzua Bridge, once an important transportation link and landmark for the region’s identity and heritage. Once the bridge fell out of use in the late 1950s, the Kinzua Bridge State Park was created to promote tourism and highlight the region’s history and exceptional natural landscapes. Yet,

An innovative design of microbial electrolytic reactor (MER) coupled with Ipomoea aquatica Forsk. plant microbial fuel cell (IAF-PMFC) was developed for azo dye wastewater treatment and electricity generation. This study aims to assess the sequential degradation of azo dye and the feasibility of energy self-sufficiency in the MER/IAF-PMFC system. The decomposition of azo dye into aromatic amines a

Minimizing the fiber property distribution would have the potential to improve the pulp properties and the process efficiency of chemimechanical pulp. To achieve this, it is essential to improve the level of knowledge of how evenly distributed the sulfonate concentration is between the individual chemimechanical pulp fibers. Due to the variation in quality between pulpwood and sawmill chips, as we

Recent research has revealed that interdisciplinary work combining archaeological and heritage practice continues to be limited by enduring assumptions separating the two fields. Traditional structures and institutional barriers make it difficult to break away from what is expected in order to explore what is possible in what archaeologists and heritage practitioners ‘do’. Though archaeologists pl

In this article we analyse the actions of Royal Dutch/Shell (since 2021, Shell) considering the campaign against them and their operations in Nigeria in the mid-1990s. Using the concept counter-frames we analyse Shell's internal documentation of the campaign to understand how a multinational extractive industry engaged in disputes of legitimacy and against critiques of their operations. Focusing o

Equine Assisted Therapy (EAT) has positive influence on health. However, research is scarce regarding how people with mental health problems experience EAT and if it influences occupational engagement. Eleven people with mental health problems were interviewed regarding this issue. Data was analyzed using a hermeneutic phenomenological approach. Results showed that EAT had a positive influence on

Background: The physical risks involved in donating hematopoietic stem cells have been thoroughly studied, but little is known about the psychological risks potential donors might face before donation. The aim of this study was to describe potential the pre-donation worries and psychological well-being of hematopoietic stem cell donors and investigate possible associations between donor characteri

Purpose: The purpose of the study was to describe the design and implantation of a branched stent-graft during endovascular aortic repair incorporating double-cuff bidirectional inner branch. Technique: A new double-cuff bidirectional antegrade and retrograde inner branched stent-graft with large diamond-shaped fenestration was designed for incorporation of a splenic artery. The inner cuffs of the