In this paper, an amphiphilic peptide dendrimer with potential applications against multi-resistant bacteria such as Staphylococcus aureus was synthesized and studied on model cell membranes. The combination of quartz crystal microbalance and atomic force microscopy imaging during continuous flow allowed for in situ monitoring of the very initial interaction processes and membrane transformations

Background: Children born very preterm (PT) after fetal growth restriction (FGR) exhibit cognitive impairment at early school age. The relationship between neurodevelopmental impairment and attained regional brain volumes is unknown. Methods: We studied 23 preterm children with FGR (PT-FGR), 24 matched preterm children AGA (PT-AGA), and 27 matched term AGA children (T-AGA) by measuring brain volum

Human carbonic anhydrase IX (CA IX) is a multi-domain membrane protein that is therefore difficult to express or crystalize. To prepare crystals that are suitable for neutron studies, we are using only the catalytic domain of CA IX with six surface mutations, named surface variant (SV). The crystallization of CA IX SV, and also partly deuterated CA IX SV, was enabled by the use of microseed matrix

Aims: Chronic left atrial enlargement (LAE) increases the risk of atrial fibrillation. Electrocardiogram (ECG) criteria might provide a means to diagnose LAE and identify patients at risk; however, current criteria perform poorly. We seek to characterize the potentially differential effects of atrial dilation vs. hypertrophy on the ECG P-wave. Methods and results: We predict effects on the P-wave

This paper explores and assesses power loss generation and heat extraction in a stator with directly air-cooled laminated winding. An electrical machine winding made of an electric conducting sheet, which have slotted structure for accommodating a magnetic core, is denoted a laminated winding. A space is introduced between the conducting sheets so that the heating power is removed right where it i

As a form of active transport, cycling provides significant health benefits to the elderly. Among voluminous active transport-related literature, few studies have investigated the correlates of the cycling activity of urban elderly. This study explored the effects of individual, household, and built environment attributes on the frequency of cycling trips by urban elderly, with data collected from

Purpose: Most patients recover well from a distal radius fracture (DRF). However, approximately one-fifth have severe disability after 1 year when evaluated using the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire. In the present study, we evaluated this subgroup of patients in our register with an inferior outcome. We hypothesized that the patient-reported outcome would improve

Torgny Roxå and Katarina Mårtensson note that the achievement of teaching excellence is intrinsically linked with organizational structures that recognize and reward excellence. They suggest that understanding organizational structures is important in the extent to which they have the potential to either promote or jeopardize excellence. Using the three principles for governance – collegial, manag

Heritopia explores the multiple meanings of the past in the present, using the famous temples of Abu Simbel and other World Heritage sites as points of departure. It employs three perspectives in its attempt to understand and explain both past and present: the truth of knowledge, the beauties of narrative, and ethical demands. Crisis theories are rejected as nostalgic expressions of contemporary s

Ett antal rapporter under senare år har uppmärksammat oss på hur farlig ensamhet är för hälsan. Enligt vissa studier är den till och med farligare än rökning. Särskilt utsatta är äldre. Larmrapporterna har lett till flera debattinlägg, där man menar att politikerna måste ta ett större ansvar. Vissa pekar på Storbritannien, där man har inrättat en särskild ensamhetsminister. Men är ensamheten verkl

Agriculture and animal production have a great environmental impact, which is steadily growing. In a previous article, we highlighted how biodiversity is vital for agricultural production, emphasizing the role of animal pollinators. Here, we discuss the different dimensions of food security and the key role of our food choices in the cities to drive land use in rural areas and minimize the environ

Fluctuation relations are powerful equalities that hold far from equilibrium. However, the standard approach to include measurement and feedback schemes may become inapplicable in certain situations, including continuous measurements, precise measurements of continuous variables, and feedback induced irreversibility. Here we overcome these shortcomings by providing a recipe for producing detailed

Estuarine sediments are key sites for removal of phosphorus (P) from rivers and the open sea. Vivianite, an Fe(II)-P mineral, can act as a major sink for P in Fe-rich coastal sediments. In this study, we investigate the burial of P in the Öre Estuary in the northern Baltic Sea. We find much higher rates of P burial at our five study sites (up to ĝ1/4 0.145 molĝ€†mĝ'2ĝ€†yrĝ'1) when compa