During the 99 years of its history, the Journal of Comparative Physiology A has published many of the most influential papers in comparative physiology and related disciplines. To celebrate this achievement of the journal’s authors, annual Editors’ Choice Awards and Readers’ Choice Awards are presented. The winners of the 2023 Editors’ Choice Awards are ‘Contact chemoreception in multi‑modal sensi

Background: Diabetes is associated with systemic complications. Prevalence of diabetic nephropathy, and retinopathy, in type 1 diabetes is declining but it is not known if this is true also for diabetic neuropathy. Aim: To investigate the relationship between large fiber diabetic neuropathy and other diabetic complications. Materials and methods: Neuropathy, defined here as large fiber neuropathy,Background: Diabetes is associated with systemic complications. Prevalence of diabetic nephropathy, and retinopathy, in type 1 diabetes is declining but it is not known if this is true also for diabetic neuropathy.Aim: To investigate the relationship between large fiber diabetic neuropathy and other diabetic complications.Materials and methods: Neuropathy, defined here as large fiber neuropathy, w

Dissolved Organic Carbon (DOC) in inland waters plays an essential role in the global carbon cycle and has significant public health effects. Machine learning (ML) together with remote sensing has emerged as a powerful and promising combination to quantify water quality parameters from space. However, inland water sample data for DOC is limited. Hence, little is known about the potential to quanti

Background: The impact of pre-antiretroviral treatment (ART) HIV-RNA on time to successful virological suppression and subsequent failure in HIV patients remains poorly investigated. Methods: We used the Swedish InfCareHIV database and the Danish HIV Cohort Study to evaluate impact of pre-ART HIV-RNA on primary virological suppression (HIV-RNA < 50copies/ml) and risk of secondary virological failu

Context: Outcomes in renal cell carcinoma (RCC) are reported inconsistently, with variability in definitions and measurement. Hence, it is difficult to compare intervention effectiveness and synthesise outcomes for systematic reviews and to create clinical practice guidelines. This uncertainty in the evidence makes it difficult to guide patient-clinician decision-making. One solution is a core out

We report on the discovery of three transiting super-Earths around K2-155 (EPIC 210897587), a relatively bright early M dwarf (V = 12.81 mag) observed during Campaign 13 of the NASA K2 mission. To characterize the system and validate the planet candidates, we conducted speckle imaging and high-dispersion optical spectroscopy, including radial velocity measurements. Based on the K2 light curve and

We present the detection and follow-up observations of planetary candidates around low-mass stars observed by the K2 mission. Based on light-curve analysis, adaptive-optics imaging, and optical spectroscopy at low and high resolution (including radial velocity measurements), we validate 16 planets around 12 low-mass stars observed during K2 campaigns 5-10. Among the 16 planets, 12 are newly valida

We present the discovery of three small planets transiting K2-136 (LP 358 348, EPIC 247589423), a late K dwarf in the Hyades. The planets have orbital periods of 7.9757 ± 0.0011, 17.30681-0.00036+0.00034, and 25.5715-0.0040+0.0038 days, and radii of 1.05 ± 0.16, 3.14 ± 0.36, and 1.55-0.21+0.24 R⊕, respectively. With an age of 600-800 Myr, these planets are some of the smallest and youngest transit

We report the discovery in K2's Campaign 10 of a transiting terrestrial planet in an ultrashort- period orbit around an M3-dwarf. K2-137 b completes an orbit in only 4.3 h, the second shortest orbital period of any known planet, just 4 min longer than that of KOI 1843.03, which also orbits an M-dwarf. Using a combination of archival images, adaptive optics imaging, radial velocity measurements, an

Background: Brain metastases are associated with considerable negative effects on patients’ outcome in lung adenocarcinoma (LADC). Here, we investigated the proteomic landscape of primary LADCs and their corresponding brain metastases. Materials and methods: Proteomic profiling was conducted on 20 surgically resected primary and brain metastatic LADC samples via label-free shotgun proteomics. Afte

Mandolin AB är ett praktikfall i bokföring, bokslut och ekonomisk analys. I praktikfallet ingår att sköta den löpande bokföringen, ta fram bokslut och årsredovisning samt att göra ekonomiska analyser av företaget Mandolin AB. Praktikfallet syftar till att ge ett helhetsperspektiv på arbetet med ekonomisk rapportering i ett mindre företag, inklusive praktisk kunskap om och förståelse för bokförings

We report the discovery of a new ultra-short-period planet and summarize the properties of all such planets for which the mass and radius have been measured. The new planet, K2-131b, was discovered in K2 Campaign 10. It has a radius of and orbits a G dwarf with a period of 8.9 hr. Radial velocities obtained with Magellan/PFS and TNG/HARPS-N show evidence for stellar activity along with orbital mot

We report on the discovery of three transiting planets around GJ 9827. The planets have radii of 1.75±0.18, 1.36±0.14, and 2.11 0.21 0.22 - + R⊕, and periods of 1.20896, 3.6480, and 6.2014 days, respectively. The detection was made in Campaign 12 observations as part of our K2 survey of nearby stars. GJ 9827 is a V = 10.39 mag K6V star at a distance of 30.3±1.6 parsecs and the nearest star to be f

Aims. Planets in the mass range from 2 to 15 M⊙ are very diverse. Some of them have low densities, while others are very dense. By measuring the masses and radii, the mean densities, structure, and composition of the planets are constrained. These parameters also give us important information about their formation and evolution, and about possible processes for atmospheric loss. Methods. We determ

HD 3167 is a bright (V = 8.9 mag) K0 V star observed by NASA's K2 space mission during its Campaign 8. It has recently been found to host two small transiting planets, namely, HD 3167b, an ultra-short-period (0.96 days) super-Earth, and HD 3167c, a mini-Neptune on a relatively long-period orbit (29.85 days). Here we present an intensive radial velocity (RV) follow-up of HD 3167 performed with the

We present radial velocity follow-up observations of K2-19, a compact planetary system hosting three planets, of which the two larger ones, K2-19b and K2-19c, are close to the 3:2 mean motion resonance. An analysis considering only the radial velocity measurements detects K2-19b, the larger and more massive planet in the system, with a mass of 54.8 ± 7.5M⊕ and provides a marginal detection of K2-1

Pseudohypertrophy of musculus tensor fascia lata presenting as a soft tissue tumor: a case report Conditions presenting as palpable soft tissue masses are a common clinical issue. This case report describes a patient with unilateral pseudohypertrophy of m. tensor fasciae latae, which is an uncommon differential diagnosis for a palpable soft tissue mass. The patient presented a palpable soft tissue

Flicker can be annoying, but above all it can have a negative effect on human health; causing irritation, headaches, eye strain and migraines. With the introduction of LED lamps, flicker has once again become a problem. In addition to the unnecessary suffering caused to individuals, the negative consequences create an obstacle to the wide and rapid adoption of new LED technology and thus also an oFlicker can be annoying, but above all it can have a negative effect on human health; causing irritation, headaches, eye strain and migraines. With the introduction of LED lamps, flicker has once again become a problem. In addition to the unnecessary suffering caused to individuals, the negative consequences create an obstacle to the wide and rapid adoption of new LED technology and thus also an o

Flimmer kan vara irriterande, men framför allt kan det ha en negativ effekt på människors hälsa, orsaka irritation, huvudvärk, ögonansträngning och migrän. I och med införandet av LED-lampor har flimmer åter blivit ett problem. Förutom det onödiga lidande flimmer orsakar hos individer, skapar de negativa konsekvenserna ett hinder för bred och snabb anpassning av den nya LED-tekniken och därmed ock

This thesis explores the use of data mining and AI-tailored frameworks for extracting public health evidence from large health datasets. The research presented in this thesis demonstrates the potential of these tools for automating and simplifying the data mining process, and for providing valuable insights into various public health issues.In Paper I, we used data mining and natural language proc